A5075882164- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Oral and Maxillofacial Pathology
- Oral and gingival health research
- Dental Radiography and Imaging
- Bone Tissue Engineering Materials
- Orthodontics and Dentofacial Orthopedics
- Reconstructive Surgery and Microvascular Techniques
- Hemostasis and retained surgical items
- Oral microbiology and periodontitis research
- Bone Tumor Diagnosis and Treatments
- Dental materials and restorations
- Tumors and Oncological Cases
- Dental Anxiety and Anesthesia Techniques
- Mesenchymal stem cell research
- dental development and anomalies
- Electrospun Nanofibers in Biomedical Applications
- Healthcare professionals’ stress and burnout
- Dental Research and COVID-19
- Endodontics and Root Canal Treatments
- Facial Trauma and Fracture Management
- Ear and Head Tumors
- Layered Double Hydroxides Synthesis and Applications
- Surgical Sutures and Adhesives
- Salivary Gland Tumors Diagnosis and Treatment
University of Naples Federico II
2015-2025
Federico II University Hospital
2007-2014
Platelet concentrates for surgical topical applications are nowadays often used, but quantification of the long-term growth factor release from these preparations in most cases is impossible. Indeed, protocols, platelets massively activated and there no significant fibrin matrix to support cell migration. Choukroun's platelet-rich (PRF), a second generation platelet concentrate, leucocyte- biomaterial. Here, we show that this dense membrane releases high quantities three main factors...
Containment measures adopted to reduce the spread of coronavirus disease 2019 (COVID-19) have produced a general perception job insecurity. Dentists been highly affected by such measures, as they represent an easy source contagion. As perceived insecurity is associated with psychological distress and Italian dentists COVID-19 outbreak in terms potential financial loss risk being infected, this study aimed at assessing whether fear moderated effect on depressive symptoms. This cross-sectional...
To assess the relevance of simultaneous sinus-lift and implantation with leukocyte- platelet-rich fibrin (L-PRF, Choukroun's technique) as sole subsinus filling material.Twenty-three lateral sinus elevations (SA4 sinus) were performed on 20 patients implant placement. Seven treated 19 Astra implants (AstraTech, Mölndal, Sweden) 13 33 Intra-Lock (Intra-Lock Ossean, Boca Raton, FL). L-PRF membranes used to cover Schneiderian membrane, tips served "tent pegs" for L-PRF-patched membranes, cavity...
Extensive bone grafting remains a delicate procedure, because of the slow and difficult integration grafted material into physiological architecture. The recent use platelet concentrates aims to improve this process by accelerating mucosal healing. Choukroun's platelet-rich fibrin (PRF) is healing biomaterial that in single autologous membrane, most platelets, leukocytes, cytokines from 10 mL blood harvest, without artificial biochemical modification (no anticoagulant, no bovine thrombin)....
The aim of this study was to evaluate the effects leukocyte- and platelet-rich fibrin (L-PRF) on pain soft tissue healing after tooth extractions. Twenty-six patients (9 males 17 females) were treated with multiple extractions (2 8), a total 108 This an exploratory single blinded randomized clinical trial split-mouth design. surgery assessed in each patient by VAS scale (1 10) at intervals 24-48-72-96 hours. clinically evaluated 3, 7, 14, 21 days same examiner surgeon, using modified Healing...
Extensive bone grafting remains a delicate procedure, due to the slow and difficult integration of grafted material into physiological architecture. The recent use platelet concentrates aims improve this process by accelerating mucosal healing. Choukroun's platelet-rich fibrin (PRF) is healing biomaterial that in single autologous membrane, most platelets, leukocytes, cytokines from 10-mL blood harvest, without artificial biochemical modification (no anticoagulant, no bovine thrombin). In...
Leukocyte- and platelet-rich fibrin (L-PRF) is a biomaterial commonly used in periodontology implant dentistry to improve healing tissue regeneration, particularly as filling material alveolar sockets regenerate bone for optimal dental placement. The objective of this work was evaluate the use L-PRF safe hemostatic after extractions (or avulsions) prevention hemorrhagic complications heart surgery patients without modification anticoagulant oral therapy. Fifty under therapy who needed were...
Platelet derivatives are commonly used in wound healing and tissue regeneration. Different procedures of platelet preparation may differentially affect growth factor release cell growth. Preparation platelet-rich fibrin (PRF) is accompanied by factors, including platelet-derived (PDGF), vascular endothelial (VEGF) transforming β1 (TGFβ1), several cytokines. When compared with the standard procedure for plasma (PRP), PRF released 2-fold less PDGF, but >15-fold >2-fold VEGF TGFβ1,...
In this multicenter study, submerged implants were prospectively followed to evaluate their long-term prognosis in irradiated patients. a total of 77 patients treated for oral or neck cancer, 188 consecutively placed. After healing period, the successfully integrated restored with 69 removable and 38 fixed restorations. The cumulative survival success rates evaluated over period at least 36 months. addition, calculated implant subgroups divided per site (mandible maxilla), radiation dosage,...
ABSTRACT Adipose tissue‐derived mesenchymal stem cells (Ad‐MSC) and platelet derivatives have been used alone or in combination to achieve regeneration of injured tissues. We tested the effect platelet‐rich plasma (PRP) on Ad‐MSC adipocyte function. PRP increased viability, proliferation rate G1‐S cell cycle progression, by at least 7‐, 2‐, 2.2‐fold, respectively, reduced caspase 3 cleavage. Higher concentrations PRPs derived from individuals with higher counts were more effective increasing...
Abstract Dental anxiety is a crucial problem for dentistry because it may represent significant risk to oral health. Different factors, whether non‐cognitive (e.g., traumatic dental events) or cognitive the patient's subjective perceptions), cause anxiety. However, previous studies have assessed these factors as independent predictors of anxiety, without providing any exploration potential mediational pathways. The current study role certain dimensions (i.e., dentist's perceived...