- Neurotransmitter Receptor Influence on Behavior
- Forensic Toxicology and Drug Analysis
- Cancer-related molecular mechanisms research
- Cancer Cells and Metastasis
- Hormonal and reproductive studies
- RNA modifications and cancer
Peking University
2021
Shanghai Medical College of Fudan University
2021
Center for Life Sciences
2021
Fudan University
2021
Background: Dopamine transporter (DAT) and serotonin (SERT) are targets for many psychoactive substances. Functional assays including uptake inhibition release often involve radiolabeled compounds like [ 3 H]-dopamine H]-serotonin to assess drug activity at transporters, which have high requirements on handling radioactive samples. Aims: The aim of this study was establish a label-free method DAT SERT. Methods: A liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS)...