A5089977735- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Reconstructive Surgery and Microvascular Techniques
- Neuroscience and Neural Engineering
- Muscle activation and electromyography studies
- Breast Implant and Reconstruction
- Lymphatic System and Diseases
- Peripheral Nerve Disorders
- EEG and Brain-Computer Interfaces
- Diagnosis and Treatment of Venous Diseases
- Wound Healing and Treatments
- Cardiovascular Function and Risk Factors
- Pain Management and Treatment
- Orthopedic Surgery and Rehabilitation
- Migraine and Headache Studies
- Sympathectomy and Hyperhidrosis Treatments
- Breast Cancer Treatment Studies
- Organ and Tissue Transplantation Research
- Burn Injury Management and Outcomes
- Body Contouring and Surgery
- Trigeminal Neuralgia and Treatments
- Reconstructive Facial Surgery Techniques
- Ophthalmology and Eye Disorders
- Surgical Sutures and Adhesives
- Colorectal Cancer Surgical Treatments
University of Michigan–Ann Arbor
2016-2025
Michigan Medicine
2016-2025
University Health System
2014-2024
Plastic Surgery Hospital
2016-2024
Creative Commons
2017-2023
Ann Arbor Center for Independent Living
2011-2021
A. Alfred Taubman Health Care Center
2011-2021
Associated Research (United States)
2018-2019
United States Department of Veterans Affairs
2019
Health Services Research & Development
2019
Background: Originally designed for prosthetic control, regenerative peripheral nerve interfaces (RPNIs) prevent neuroma formation by providing free muscle grafts as physiological targets ingrowth. We report the first series of patients undergoing RPNI implantation treatment symptomatic postamputation neuromas. Methods: A retrospective case all amputees neuromas between November 2013 and June 2015 is presented. Data were obtained via chart review phone interviews using questions derived from...
After studying this article, the participant should be able to: 1. Discuss key points in diagnosing lymphedema. 2. Understand imaging modalities that facilitate diagnosis and surgical planning. 3. Appreciate indications for both physiologic ablative procedures. 4. Recognize potential role of lymphaticovenular anastomosis vascularized lymph node transfer treatment patients with lymphedema.Lymphedema is an incurable disease caused by insufficient lymphatic drainage leading to abnormal...
The rat infarct model is widely used in heart failure research, but few echocardiographic indexes of left ventricular (LV) function are validated this model. Accordingly, the objective study was to validate a 13-segment LV wall motion score index (WMSI) and myocardial performance (MPI) infarcted rats. Twenty-nine male Wistar rats underwent coronary artery ligation or sham operation were evaluated with two-dimensional Doppler flow echocardiography 8 wk later. After echocardiography, invasive...
Summary: Regenerative peripheral nerve interface (RPNI) surgery has been demonstrated to be an effective tool as for neuroprosthetics. Additionally, it shown a reproducible and reliable strategy the active treatment prevention of neuromas. The purpose this article is provide comprehensive review RPNI demonstrate its simplicity empower reconstructive surgeons add their armamentarium. This discusses basic science neuroma formation prevention, well theory RPNI. An anatomic discussion surgical...
Objective: The objective was to assess the postsurgical outcomes of regenerative peripheral nerve interface (RPNI) surgery in a prospective cohort major lower extremity amputation patients with chronic postamputation pain. Background: Chronic pain limb is commonly result neuroma formation after traumatic injury. By implanting more proximal transected ends into autologous free muscle grafts, RPNI can treat by diminishing development neuromas. prior retrospective studies has been shown...
Abstract Individuals with severe neurological injuries often rely on assistive technologies, but current methods have limitations in accurately decoding multi-degree-of-freedom (DoF) movements. Intracortical brain-machine interfaces (iBMIs) use neural signals to provide a more natural control method, currently struggle higher-DoF movements—something the brain handles effortlessly. It has been theorized that simplifies high-DoF movement through muscle synergies, which link multiple muscles...
Intracardiac accumulation of lipid and related intermediates (e.g., ceramide) is associated with cardiac dysfunction may contribute to the progression heart failure (HF). Overexpression nuclear receptor peroxisome proliferator-activated receptor-alpha (PPARalpha) increases intramyocellular ceramide left ventricular (LV) dysfunction. We tested hypothesis that activation fatty acid metabolism fat feeding or a PPARalpha agonist myocardial triglyceride and/or exacerbates LV in HF. Rats...
Background: Little knowledge exists concerning replantation following traumatic major upper extremity amputation. This study characterizes the injury patterns and outcomes of patients suffering amputation ascertains clinical factors associated with decision to attempt replantation. Methods: A retrospective cohort was conducted on treated at a Level I trauma center between June 2000 August 2011. Patients who experienced or proximal radiocarpal joint were included in study. The subset...
Common peroneal nerve palsy leading to foot drop is difficult manage and has historically been treated with extended bracing expectant waiting for return of function. Peroneal exploration traditionally avoided except in cases known traumatic or iatrogenic injury, tendon transfers being performed a delayed fashion after exhausting conservative treatment. We present new strategy management concomitant transfer.We retrospectively reviewed series 12 patients palsies that were transfer from 2005...
Background: A neuroma occurs when a regenerating transected peripheral nerve has no distal target to reinnervate. Symptomatic neuromas are common cause of postamputation pain that can lead substantial disability 1–3 . Regenerative interface (RPNI) surgery may benefit patients through the use free nonvascularized muscle grafts as physiologic targets for reinnervation mitigation and pain. Description: An RPNI is constructed by implanting end into skeletal graft. The or affected identified,...