A5032350407- Blood Coagulation and Thrombosis Mechanisms
- RNA Interference and Gene Delivery
- interferon and immune responses
- Consumer Behavior in Brand Consumption and Identification
- Infectious Diseases and Tuberculosis
- Cancer-related gene regulation
- South Asian Studies and Conflicts
- Airway Management and Intubation Techniques
- Blood groups and transfusion
- Kruppel-like factors research
- Protease and Inhibitor Mechanisms
- Apelin-related biomedical research
- Nonlinear Optical Materials Studies
- Oral and gingival health research
- Photoreceptor and optogenetics research
- Tuberculosis Research and Epidemiology
- Cardiac Arrest and Resuscitation
- Renal and related cancers
- Platelet Disorders and Treatments
- Paraoxonase enzyme and polymorphisms
- MicroRNA in disease regulation
- Immune Response and Inflammation
- Cystic Fibrosis Research Advances
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Blood properties and coagulation
University of Missouri
2024
COMSATS University Islamabad
2022
Delft University of Technology
2022
Leiden University Medical Center
2010-2013
New York University Press
2010
Pakistan Army
2010
University of Wisconsin–Madison
2010
Highland Community College - Illinois
2010
Energy Center of Wisconsin
2010
Hepatocyte nuclear factor 4α (HNF4α) and CCAAT/enhancer-binding protein α (C/EBPα) are important for the transcriptional control of coagulation factors. To determine in vivo direct role HNF4α C/EBPα genes encoding factors, a synthetic small interfering (si)RNA approach was used that enabled strong reduction mouse hepatic under conditions minimized target-related secondary effects. For both C/EBPα, intravenous injection specific siRNAs (siHNF4α siC/EBPα) resulted more than 75% their liver...
The cytokine interleukin 1(IL-1) initiates a wide range of proinflammatory cascades and its inhibition has been shown to decrease inflammation in variety diseases. IL-1 receptor accessory protein (IL-1RAcP) is an indispensible part the IL-1R complex that stabilizes IL-1/IL-1R interaction plays important role signal transduction complex. soluble form IL-1RAcP (sIL-1RAcP) contains only extracellular domain serves as natural inhibitor signaling. Therefore, increasing sIL-1RAcP levels might be...
Single nucleotide polymorphisms (SNPs) in a 4q35.2 locus that harbors the coagulation factor XI (F11), prekallikrein (KLKB1), and cytochrome P450 family member (CYP4V2) genes are associated with deep venous thrombosis (DVT). These SNPs exert their effect on DVT by modifying circulating levels of FXI. However, were not necessarily all F11, but also KLKB1 CYP4V2. Here, we searched for evidence common regulatory elements within locus, outside F11 gene, might control FXI plasma and/or risk. To...
A rapid sequence intubation (RSI) method was introduced to a university-based emergency medical services (EMS) system. This is report of the initial experience with first 50 patients in unique, two-tiered, two advanced life support (ALS) providers system.The data were evaluated prospectively after an extensive RSI training period, consisting didactic information and skills performance. Fifty consecutive patient records that documented procedure abstracted. Data abstracted included end-tidal...
The unprecedented economic growth in recent decades has cultivated the exploitation of natural resources and over-consumption, leading to ecological deterioration sustainability. ever-increasing consumption developing countries is creating a significant environmental strain. Thus, industry consumers' issues their harmful effects on human health have led concerns among researchers, scientists, academic communities, policymakers. present work examines impact different value factors sustainable...
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In deep tissue imaging, pulsed near-infrared lasers commonly provide high peak powers needed for nonlinear absorption, but average power and linear absorption can be limiting factors damage through heat. We implemented intra-cavity dumping within a mode-locked Ti:Sapphire laser used two-photon computer generated holography stimulation. This system enables photostimulation in which pulse energy, power, repetition rate each varied harnessed as degrees of freedom. demonstrate how this provides...