The antiproliferative and antimicrobial effects of thirteen compounds isolated from Inula viscosa (L.) were tested in this study. activity was against three cell lines using the MTT assay. microdilution method used to study two Gram positive bacteria, negative bacteria one fungus. apoptotic determined a TUNEL colorimetric Scanning electron microscopy morphological changes treated cancer cells bacteria. Antiproliferative observed four flavonoids (nepetin, 3,3′-di-O-methylquercetin,...

The novel seco-ursane-type triterpenoid 3β,11α-dihydroxy-17,22-seco-17(28), 12-ursadien-22-oic acid (1) was isolated for the first time from a natural source two Salvia species growing wild in Jordan, palaestina Benth. and syrica L. In addition to compound 1, S. syriaca afforded new sesquiterpene named syriacine (2). also 15 other known compounds, 6 of which are plant, these include velutin, hyptadienic acid, cirsilineol, 2α,3β-dihydroxyurs-12-en-28-oic...

Four new and 14 known compounds have been isolated from Inula viscosa of Jordanian origin. The isolates are 11(13)-eudesmen-12-oic acids, 3beta-hydroxyilicic acid (1), 3alpha-hydroxy-epi-ilicic (2), 2alpha-hydroxyilicic (3) 9beta-hydroxy-2-oxoisocostic (4).

Investigation of Capparis spinosa Jordanian origin lead to isolation two new compounds beta-sitosterylglucoside-6'-octadecanoate (1) and 3-methyl-2-butenyl-beta-glucoside (2). Linked Scan MS measurements were used propose a mass fragmentation pattern for the alkaloid Cadabicine isolated here second time from nature.

The isolation for the first time from Artemisia judaica L. (Compositae) of known flavone, cirsimaritin (5,4′-dihydroxy-6,7-dimethoxyflavone), its identification, and biological effects on isolated guinea-pig ileum are described. Small concentrations (2 ×10-6 M to 2 × 10-5M) have no observed phasic contractions or tone ileum. Larger (up 3 10-4M), however, cause a concentration-dependent inhibition amplitude reduce this preparation. Cirsimaritin also causes shift right in concentration-effect...

Ammodaucus leucotrichus L. (Apiaceae) is a rarely investigated important medicinal plant endemic to North African countries. The essential oil of A. seeds obtained by hydro-distillation and SPME extraction methods were analyzed Gas Chromatography-Mass Spectrometry (GC-MS) technique. Twenty two components identified in the hydro-distilled amounting 97.04 % total content. was dominated oxygenated monoteprenes (87.32 %) represented perilla aldehyde (84.43 %). A thirty four accounting for 99.88...

Investigation of the chemical constituents Aristolochia maurorum growing wild in Jordan resulted isolation and characterisation one new compound addition to 19 known compounds. The was identified as aristolochic acid II alanine amide (14). other compounds were following: palmitic (1), β-sitosterol (2), E-ethyl-p-coumarate (3), Z-ethyl-p-coumarate (4), IV methyl ester (5), aristolactam I (6), loliolide (7), (+)-dehydrovomifoliol (8), glycerol-1-palmitate (9), (10), E-p-coumaric (11),...

Phytochemical investigation of the chemical constituents aerial parts Scabiosa prolifera L. led to isolation one new flavonol glycoside, kaempferol-3-O-(4″,6″-di-E-p-coumaroyl)-β-D-galactopyranoside (1), along with ten other known compounds including luteolin-7-O-(2″-O-ethyl-β-glucopyranoside), β-sitosterol, β-sitosterylglucoside, ursolic acid, corosolic acid 3-O-β-D-arabinopyranoside, apigenin, methyl-α-D-glucopyranoside, luteolin-7-O-β-glucopyranoside and isoorientin. The structures all...

Two new cardenolides, named ischarin and ischaridin in addition to 10 known compounds, were isolated from Calotropis procera Ait. (Asclepiadaceae), growing wild Jordan. Their structures established mainly by the extensive application of one- two-dimensional (1)H (13)C-NMR spectroscopy.

Three new seco-ursadiene triterpenoids 1–3 together with 11 known compounds were isolated from Salvia syriaca of Jordanian origin. The identified by using NMR spectroscopy including extensive 2D experiments and mass spectrometry. structure compound 3 was confirmed X-ray crystallography, the information thus obtained used to confirm stereochemistry 1 2. This is second report 17,22-seco-17(28),12-ursadien-22-oic acids.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFive New Alkaloids from Colchicum ritchiiAlan J. Freyer, Musa H. Abu Zarga, Sadiqa Firdous, Hélène Guinaudeau, and Maurice ShammaCite this: Nat. Prod. 1987, 50, 4, 684–689Publication Date (Print):July 1, 1987Publication History Published online1 July 2004Published inissue 1 1987https://pubs.acs.org/doi/10.1021/np50052a018https://doi.org/10.1021/np50052a018research-articleACS PublicationsRequest reuse permissionsArticle...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Natural Colchicinoids: Indications of Two Possible Catabolic Routes for the Colchicine AlkaloidsTaleb H. Al-Tel, Musa Abu Zarga, Salim S. Sabri, Alan J. Freyer, and Maurice ShammaCite this: Nat. Prod. 1990, 53, 3, 623–629Publication Date (Print):May 1, 1990Publication History Published online1 July 2004Published inissue 1 May 1990https://doi.org/10.1021/np50069a013RIGHTS & PERMISSIONSArticle Views190Altmetric-Citations21LEARN ABOUT THESE...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Spectral Method for the Determination of Position a Phenolic Group on Ring A an Aporphine. Four New Aporphines From Polyalthia acuminataMusa H. Abu Zarga and Maurice ShammaCite this: J. Nat. Prod. 1982, 45, 4, 471–475Publication Date (Print):July 1, 1982Publication History Published online1 July 2004Published inissue 1 1982https://pubs.acs.org/doi/10.1021/np50022a020https://doi.org/10.1021/np50022a020research-articleACS PublicationsRequest reuse...

Abstract Investigation of the aerial parts Sisymbrium irio L. (Cruciferea) collected in northern Jordan afforded two new compounds, sitosteryl-6′-O-undecanoate-β-D-glucoside (1) and (Z)-8,11,12-trihydroxyoctadec-9-enoic acid (2), addition to 12 known 10 which are reported for first time from plant. The structures all compounds were established by spectroscopic chemical methods. Keywords: crotanoyl cosmosiinCrucifereanaringenin-4′-O-β-glucopyranoside Acknowledgement authors would like thank...

Phytochemical investigation of Osyris alba L. (Santalaceae) Jordanian origin resulted in the isolation and identification one new pyrrolizidine alkaloid, osyrisine (1), together with 16 other known compounds. The structures all compounds were established on basis spectroscopic analysis. Osyrisine, catechin, catechin-3-O-α-l-rhamnopyranoside exhibited a significant level antiparasitic activity against two parasites, Entamoeba histolytica Giardia intestinalis.

Seventeen compounds, including a new lanostane triterpenoid, 24(Z)-1β-3β-dihydroxyeupha-7,24-dien-26-oic acid, have been isolated from the methanolic extracts of two samples Jordanian propolis collected different places with dominant flora. The structures compounds were elucidated by spectral methods IR, UV, MS and 1- 2-D NMR.

Investigation of the chemical constituents Salvia judaica growing wild in Jordan led to isolation and identification 15 known compounds. These included: luteolin-3′-methyl ether (1), indole-3-carboxyaldehyde (2), p-hydroxybenzaldehyde (3), tricin (4), apigenin (5), methyl isoferuloyl-7-(3,4-dihydroxyphenyl) lactate (6), rosmarinate (7), rosmarinic acid (8), salvigenin (9), β-sitosterol (10), 3β, 28-dihydroxyurs-12-ene (11), cirsilineol (12), 2,3-dihydroxyurs-12-en-28-oic (13), β-sitosteryl...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Natural Dibenzocycloheptylamine Alkaloids: A Possible Catabolic Route for the Colchicine AlkaloidsMusa H. Abu Zarga, Salim S. Sabri, Taleb Al-Tel, Atta-ur-Rahman, Zahir Shah, and M. FerozCite this: J. Nat. Prod. 1991, 54, 4, 936–940Publication Date (Print):July 1, 1991Publication History Published online1 July 2004Published inissue 1 1991https://pubs.acs.org/doi/10.1021/np50076a002https://doi.org/10.1021/np50076a002research-articleACS...