A5082950586- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neonatal and fetal brain pathology
- Cryptography and Residue Arithmetic
- Neurogenetic and Muscular Disorders Research
- Neuroscience and Neuropharmacology Research
- Coding theory and cryptography
- Infectious Encephalopathies and Encephalitis
- Neurological Complications and Syndromes
- Glycogen Storage Diseases and Myoclonus
- Medical Image Segmentation Techniques
- Face and Expression Recognition
- Metabolism and Genetic Disorders
- Congenital Anomalies and Fetal Surgery
- Child Nutrition and Feeding Issues
- Sleep and related disorders
- Image Retrieval and Classification Techniques
- Multi-Criteria Decision Making
- Image Enhancement Techniques
- Long-Term Effects of COVID-19
- Advanced Clustering Algorithms Research
- Viral Infections and Immunology Research
- Bacterial Infections and Vaccines
- Genomics and Rare Diseases
- Fuzzy Systems and Optimization
Kyungpook National University Hospital
2015-2024
Kyungpook National University
2012-2022
Yeungnam University
2002-2022
Ajou University
2015
Korea University
2015
Pusan National University Yangsan Hospital
2015
Yonsei University
2015
Daegu Gyeongbuk Institute of Science and Technology
2013
Washington State University
2013
Sungkyunkwan University
2003-2010
Antiepileptic drugs (AEDs) can adversely affect cognitive function by suppressing neuronal excitability or enhancing inhibitory neurotransmission.The main effects of AEDs are impaired attention, vigilance, and psychomotor speed, but secondary manifest on other functions.Although the long-term use obviously elicit dysfunction in epilepsy patients, their over short periods up to a year inconclusive due methodological problems.In general, cognition worse for older (e.g., phenobarbital) than...
In addition to aberrant features in the speech, children with Autism Spectrum Disorder (ASD) may present unusual responses sensory stimuli, especially auditory stimuli. We investigated ability of ASD by using Auditory Brainstem Responses (ABR) as they can directly judge both hearing status and integrity brainstem pathways. One hundred twenty-one (71: ASD; M 58/ F 13, mean age; 41.8 months, 50: control group; 41/ 9, 38 months) were included study. As compared values group, latency wave V,...
To prospectively evaluate the neuropsychological effect of levetiracetam (LVT) in comparison with carbamazepine (CBZ) and its efficacy tolerability as a monotherapy children focal epilepsy.A total 121 out 135 screened (4-16 years) were randomly assigned to LVT or CBZ groups multicenter, parallel-group, open-label trial. The study's primary endpoints defined end 52 weeks treatment, followed by analysis changes observed series follow-up neurocognitive, behavioral, emotional function tests...
In this paper, an efficient digit-serial systolic array is proposed for multiplication in finite field GF(2/sup m/) using the standard basis representation. From least significant bit first algorithm, we obtain a new dependence graph and design multiplier. If input data come continuously, can produce results at rate of one every /spl lceil/m/L/spl rceil/ clock cycles, where L selected digit size. Analysis shows that computational delay time architecture significantly less than previously...
Background: Acute necrotizing encephalopathy (ANE) is a rare, but potentially life threatening neurological condition in children.This study aimed to investigate its clinical spectrum, diagnostic and therapeutic dilemma, prognosis.Methods: Twelve children with ANE were included the study.The diagnosis was made by radiological characteristics from January 1999 December 2017 their data retrospectively analyzed.Results: A total of 12 aged 6 93 months at onset (5 male: 7 female) evaluated.The...
The risk of suicide or attempts is reported higher in people with epilepsy (PWE) than the general population. Although epileptic, psychiatric, and psychosocial factors are known for attempt, no studies have evaluated predictors severity suicidal ideation-which a warning sign attempts-in PWE. Therefore, we measured ideation its factors.Consecutive PWE who were medicated antiepileptic drugs (AEDs) attended clinic included study. subjects completed self-reported questionnaires, which Beck...
Recently, adipose tissue-derived stem cells (ASCs) were emerged as an alternative, abundant, and easily accessible source of cell therapy. Previous studies revealed losartan (an angiotensin II type I receptor blocker) treatment promoted the healing skeletal muscle by attenuation TGF-β signaling pathway, which inhibits differentiation. Therefore, we hypothesized that a combined therapy using ASCs might dramatically improve remodeling after injury. To determine effect with ASC transplantation,...
The US Food and Drug Administration approval for perampanel has only recently been expanded to patients as young 4 years, so there have few real-life studies of the effects in pediatric patients. aim this study was determine long-term efficacy, factors affecting treatment response, tolerability an add-on therapy aged years or older with epilepsy.This multicenter retrospective observational collected data from epilepsy centers four Korean national universities. Changes seizure frequency...
This study was conducted to investigate the etiology, clinical characteristics and prognosis of acute necrotizing encephalopathy (ANE) in Korean children. Six children (1 yr 7 yr) patients with ANE were enrolled. They diagnosed by radiological their data retrospectively analyzed. In a search clinically plausible causes, brain MRI all patients, mitochondrial DNA studies for encephalomyopathy, lactic acidosis, strokelike episodes (MELAS) myoclonus epilepsy ragged red fibers (MERRF) four...
ABSTRACT Objectives: To assess and compare the long‐term therapeutic response to lamivudine compared with interferon‐α (IFN‐α) in children chronic hepatitis B. Methods: A total of 40 (27 male; age, 1.3–18 y, mean, 7.7 y) B who received for at least 12 months were followed a mean period 39 (24–76) months. Their treatment efficacy was historically that 19 (14 2.1–17 y; 10 had been treated IFN‐α (24–104) Therapeutic responses 2 y after initiation either methods. Results: Two years treatment,...
Background and Purpose: Cognitive impairments are frequent consequences of epilepsy, with intellectual ability reportedly being lower in patients idiopathic generalized epilepsies than the general population.However, neuropsychological investigations have been rarely performed juvenile myoclonic epilepsy (JME).We aimed to quantify cognitive function JME using various tests.Methods: We compared 27 that healthy volunteers tests examining performance, such as verbal visual memory, frontal...
Background and Purpose: Zonisamide (ZNS) is a useful antiepileptic drug with broad therapeutic spectrum.However, there limited information on the long-term use of ZNS as monotherapy.This study investigated effects monotherapy for treatment epilepsy.Methods: We retrospectively analyzed records epilepsy patients treated at our clinic.We identified outcomes minimum 6 months.Efficacy was quantified percentage change in seizure frequency, safety assessed by frequency types adverse events.Results:...
Although benign rolandic epilepsy (BRE) is a condition, it may be associated with spectrum of behavioral, psychiatric, and cognitive disorders. This study aimed to assess the other neuropsychological profiles children BRE.In total, 23 BRE were consecutively recruited. All underwent sleep electroencephalography (EEG) assessed on battery comprehensive tests including Korean versions Wechsler intelligence scale for III, frontal executive test, rey complex figure Wisconsin card sorting attention...
The work was done to study immunogenetic peculiarities of neuroinflammatory diseases among Korean children. A total 13 children with (8 males and 5 females; mean age 4.6 +/-2.6 yr) were consecutively recruited. Geno-mic typing performed on their HLA DRB/HLA DQB genes using PCR-SSOP/SSP techniques gel immunoelectrophoresis. frequencies HLA-DR1 *15 in acute disseminated encephalomyelitis (ADEM) (31%) DQB1 *06 other (38%) significantly increased compared control subjects. HLA-DRB3 * 0202...