As astroviral infection rapidly increased in the summer of 2022 Korea, this study aimed to determine cause and genotype astroviruses during period. From January December 2022, we tested 43,312 stool samples from patients with acute gastroenteritis utilizing multiplex PCR detect HAstV. For HAstV-positive samples, determined genotypes HAstVs by sequencing. The monthly positive rate 2015 showed a notable abrupt increase HAstV between June August peaking at 9.8% July 2022. annual positivity...

Mycoplasma hominis (M. hominis) and Ureaplasma urealyticum (U. urealyticum) are important opportunistic pathogens that cause urogenital infections complicate pregnancy. The aim of this study was to investigate the prevalence, effects on pregnancy outcomes, antimicrobial susceptibilities M. U. urealyticum. We tested vaginal swabs obtained from 1035 pregnant women for presence genital mycoplasmas between June 2009 May 2014. laboratory clinical aspects infection were reviewed retrospectively,...

Infective endocarditis (IE), an infection of the endocardial surface, frequently leads to life-threatening complications, such as thromboembolism due platelet activation. We investigated mean volume (MPV) in Korean patients with IE and serial changes thereof, comparison other laboratory parameters. analyzed 248 MPV results from 22 diagnosed our hospital between January 2011 April 2012. was measured Advia 2120 (Siemens Healthcare Diagnostics, Tarrytown, NY) using EDTA-containing tubes. The...

To determine whether NMLR has more statistical strength than NLR in discriminating TB from non-TB infectious lung diseases.Among patients who underwent 3 or culture tests with molecular study between January 2016 and December 2017, 110 TB, 159 diagnosed diseases were enrolled. The original complete blood count (CBC) parameters modified CBC indices, including NMLR, analyzed.The significantly lower other diseases. However, the area under curve (AUC) for (0.90; 95% confidence interval [CI],...

Species of the genus Bacillus are a common laboratory contaminant, therefore, isolation these organisms from blood cultures does not always indicate infection. In fact, except for anthracis and cereus, most species considered human pathogens, especially in immunocompetent individuals. Here, we report an unusual presentation bacteraemia mediastinitis due to co-infection with subtilis licheniformis, which were identified by 16S RNA gene sequencing, patient oesophageal perforation.

Abstract Aim Although the etiology of plasma cell dyscrasia is poorly understood, there evidence for immune dysregulation or sustained stimulation playing a pivotal role in pathogenesis these diseases, including chronic infection and autoimmune disorders. In this study, we report four disease cases where monoclonal gammopathy ( MG ) was incidentally found during follow‐up. Methods We retrospectively reviewed medical charts laboratory test results following cases: neuromyelitis optica, K...

Acinetobacter baumannii (A. baumannii) is widely known as an opportunistic bacterial pathogen that causes infection more frequently among immunocompromised individuals. Our case demonstrated the limitation of current VITEK 2 system for idendification A. baumannii. Four clinical isolates were identified Alcaligenes faecalis by system. Misidentification might lead to unnecessary tests and inappropriate treatments. Additional methods appear be helpful accurate identification microbiology laboratories.

We report a recent case in which ciprofloxacin-resistant Shigella flexneri was isolated from 23-yr-old female patient with history of travel to India. Prior her admission our internal medicine department, she experienced symptoms high fever and generalized weakness continuous watery diarrhea that developed midway during the trip. S. stool culture. Despite initial treatment ciprofloxacin, cultures continued show growth. In susceptibility test for antibiotics quinolone family, isolate showed...

Crystalloid podocytopathy with focal segmental glomerulosclerosis in plasma cell myeloma (PCM) is rare. We present a case of crystalline deposition the bone marrow (BM) and various renal cells only proteinuria as symptom. As workup for proteinuria, biopsy sample was obtained. EM showed multiple depositions tubular podocytes. Focal crystalloid diagnosed. Because monoclonal gammopathy detected serum urine, BM study also performed. Plasma needle-shaped inclusion bodies were observed. The...

We derived a new equation to include interferon-γ (IFN-γ) levels in the QuantiFERON-Gold In-Tube (QFT-GIT) assay discriminate active tuberculosis (ATB) infection from latent TB, and compared diagnostic performance of QFT-GIT equation.From January 2013 through May 2015, we retrospectively enrolled 159 408 patients with without ATB, respectively, this study. Discriminant analysis was performed derive an distinguish ATB group non-ATB group.The sensitivity specificity for diagnosing were 90.6%...

A 51-year-old man with no specific medical history was brought to our hospital general weakness.Complete blood count results were as follows: Hb level, 12.4 g/dL; platelet count, 1,594×10 9 /L; leukocyte 16.52×10 segmented neutrophils, 65%; lymphocytes, 26%; monocytes, 3%; eosinophils, 2%; and atypical 4%.Peripheral smear showed marked increase in giant platelets hypogranulated (A).Bone marrow aspirate displayed normal erythropoiesis increased granulopoiesis, a notable finding the number of...

Aerococcus urinae is an uncommon pathogen that was first identified in 1992. Herein, we report a case of bloodstream infection caused by A. urinae, which occurred 92-year-old Korean female patient with underlying urologic who had altered consciousness. The blood culture yielded positive results for urinae; however, identifying challenging. Ultimately, used 16S ribosomal RNA (rRNA) gene sequencing to identify the organism. recovered after being treated ertapenem and meropenem. To our...

For effective blood usage and reduction of unnecessary workload at banks, we established the maximum surgical order schedule (MSBOS) for major elective surgeries evaluated indicators, including rate returned red cells (RBCs).

In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs Ge blood group system. The was detected in middle-aged woman who did not have history transfusion. Her type B+, and findings from antibody screening test revealed 1+ reactivity all panels except autocontrol. cross-matching showed incompatible results with 5 packed red cells. Additional tests confirmed anti-Ge alloantibody. While rare, cases hemolytic transfusion...

Biotin interference in immunoassays using biotin-streptavidin binding technology is well recognised by clinical laboratories, though the prevalence of elevated biotin patient populations largely unknown. We determined serum concentrations 4385 samples received sequentially 6 laboratories for routine immunoassay analysis England, and Korea, Singapore Thailand (3 countries within Asia Pacific region, APAC). Samples were initially analysed a research use-only immunoassay, with those identified...