A5102819542- Pancreatic function and diabetes
- Ovarian function and disorders
- Metabolism, Diabetes, and Cancer
- Obesity, Physical Activity, Diet
- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Lipoproteins and Cardiovascular Health
- Birth, Development, and Health
- Diabetes Management and Research
- Opioid Use Disorder Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Growth Hormone and Insulin-like Growth Factors
- Healthcare Policy and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Traditional Chinese Medicine Studies
- Cancer, Lipids, and Metabolism
- Hormonal and reproductive studies
- Ethics in Clinical Research
- Endometriosis Research and Treatment
- Diet, Metabolism, and Disease
- Hepatitis Viruses Studies and Epidemiology
- Cardiovascular Disease and Adiposity
- Nutrition and Health in Aging
- Pharmaceutical Economics and Policy
- Thyroid Disorders and Treatments
Duke University
2022-2024
Durham VA Health Care System
2024
Yonsei University
2004-2023
Severance Hospital
2023
Catholic University of Korea
2019-2020
Yeouido St. Mary's Hospital
2020
Seoul St. Mary's Hospital
2019
St. Vincent's Hospital
2018
High-intensity statin is strongly recommended in patients at very high risk (VHR) of atherosclerotic cardiovascular disease (ASCVD). However, concerns about statin-associated adverse effects result underuse this strategy practice.
The opioid overdose epidemic is escalating. Increasing access to medications for use disorder in primary care crucial. impact of the US Department Health and Human Services' policy change removing buprenorphine waiver training requirement on prescribing remains unclear. We aimed investigate providers' likelihood applying a current attitudes, practices, barriers care.
To analyze growth patterns over 2 years after birth according to preterm infant weight and length percentiles.Anthropometric measurements of 82 infants were retrospectively reviewed. Preterm with or below the 10th percentile classified as small for gestational age (SGA) (n=19) those between 89th appropriate (AGA) (n=63). The association standard deviation score (SDS) at corrected clinical factors analyzed.The SDS SGA group was significantly increased 6 months (-1.30±1.71) 24 (-0.97±1.06)...
Abstract Background The use of electronic informed consent (eIC) in decentralized trials offers a pragmatic approach to enrolling participants across multiple geographic areas. Methods Using randomized, cross-over study design, we conducted qualitative descriptive evaluation two eIC approaches—text-only and enhanced eIC—in mock hypertension Phase III clinical trial. We assessed participant comprehension acceptability (usability, satisfaction, preference). Results A total 24 individuals with...
No evidence-based interventions exist for anxiety related to pelvic exams after cancer treatment. A 3-session cognitive behavioral intervention, Pelvic Examination and Anxiety Coping Skills Empowerment (PEACE), was developed. We conducted a proof-of concept pilot study (N=16) evaluate intervention acceptability feasibility changes in pain symptoms. Participants completed 3 assessments (baseline, post-intervention, post-pelvic exam) post-exam interviews. Exploratory outcomes included...
Little information is available on the association between parents' metabolic syndrome (MetS) and adolescent offspring's obesity in Korea. The aim of our study to determine parent's obesity.The data were obtained from Korean National Health Nutrition Examination Survey conducted during 2009-2016. In present study, 3140 adolescents aged 12 18 years, their paternal pairs (PP, fathers = 2244), maternal (MP, mothers 3022) analyzed. Of these adolescents, 2637 had normal weight {age- sex-specific...
2066 Background: We evaluated the efficacy and tolerability of gemcitabine monotherapy in heavily pretreated breast cancer patients, polymorphism gemcitabine-related genes to elucidate association with toxicity. detected deoxycytidine kinase (dCK), deaminase (dCDA), ribonucleotide reductase (RNR). Methods: A weekly infusion at 850mg/m2 for 3 every 4 weeks was introduced patients who had failed previous doxorubicin taxane. Treatment delayed until leukopenia recovered G-CSF support without...
목적: 만성 B형 간염으로 치료가 필요하였던 소아청소년 중 lamivudine을 투여하면서 전향적으로 관찰한 자료를 검토하여 약제에 대한 치료 효과를 파악하고자 하였다. 방법: 2003년 6월 1일부터 2015년 10월 30일까지 가톨릭대학교 성빈센트병원 소아청소년과를 방문하여 간염의 첫 치료로 lamivudine (3 mg/kg, 최대 100 mg)을 3개월 이상 투여한 55명을 대상으로 하였다. 약제 투여 후 1개월, 3개월째, 이후는 매 3개월마다 간염 바이러스(hepatitis B virus [HBV]) 표지자, HBV-DNA, 간기능을 추적하였다. 중단은 alanine aminotransferase (ALT) 정상, HBeAg 음성 및 anti-HBe 양성 결과가 처음 발견된 시기로부터 12개월 후로 정하였다. 결과: 연구군은 남자가 31명(56.4%), 여자가 24명(43.6%)이었고, 약제의 연령은 평균 8.1세, 투여기간은 23.4개월이었다. ALT 정상화는...
Purpose : This study aimed to analyze growth patterns during the first two years after birth according weight and length percentile in children born preterm, investigate factors affecting postnatal of these children. Methods Eighty-two preterm neonates with a gestational age below 37 weeks who followed up until 24 months corrected (CA) were retrospectively reviewed. Length, head circumference measured at birth, 6, 12, 18, months. Data analyzed between small for (SGA) those appropriate (AGA)....
Purpose: To examine the association of insulin-like growth factor-1 (IGF-1) and binding protein-3 (IGFBP-3) with metabolic parameters childhood obesity assess their relationship prevalence syndrome (MetS) in childrenMethods: This was a cross-sectional study total 307 children who are subcategorized into three groups according to body mass index (BMI) percentile for age gender. (Subjects included 207 normoweight, 36 overweight, 64 obese children). Auxological profiles biochemical data...
Purpose: We investigated the difference of body mass index(BMI) score before and after gonadotropin-releasing hormone agonist (GnRHa) treatment in central precocious puberty girls(CPP). Methods: Medical records 177 girls with CPP treated GnRHa were reviewed. All patients completed therapy. The categorized into two groups according to initial BMI; normal weight group (BMI ˂ 85 percentile) overweight/obesity ≥ percentile). analyzed chronologic age (CA), bone (BA), BA advancement (BA-CA),...
Purpose:The aim of this study is to compare cut off points corrected for age and gender (CCOP) with fixed (FCOP) fasting plasma insulin Homeostatic model assessment resistance (HOMA-IR) the diagnosis IR in obese adolescents their relation metabolic abnormalities. Method: We performed a cross sectional analysis data from 195 aged 12-18 years who participated Korean National Health Nutrition Examination Survey (KNHANEA, 2009-2010). Overweight individuals were defined by BMI z score>1. Insulin...
Abstract BACKGROUND: Childhood hypocalcemia in general is caused by problems associated with calcium absorption and excretion, parathyroid hormone (PTH) secretion, vitamin D metabolism. Clinical manifestations can vary from asymptomatic to life-threatening conditions including convulsions, tetany laryngeal spasm. As many symptoms are nonspecific, laboratory tests essential for diagnosis. Nevertheless, the causes of may not be determined simple interpretation baseline calcium, phosphorus,...
Abstract Background: Autoimmune thyroid diseases (AITDs) are female predominant and the biology of sexual dimorphism is not clearly understood. Recently, GPR174 ITM2A on X chromosome have been newly suggested as autoimmune disease susceptible loci. Methods: Fourteen single nucleotide polymorphisms in immune related genes were analyzed 108 Korean children (girls =90, boys =18) with AITD [Hashimoto (HD) = 40, Graves′ (GD) 68, thyroid-associated ophthalmopathy (TAO) 37, non-TAO =60] gender...
Abstract Purpose: This study aimed to compare obesity indices with impedance analyzed body composition data, and investigate the association between data prevalence of metabolic syndrome. Methods: 123 prepubertal children (49% girls 3-to-8- year-old, 51% boys 3-to-9-year-old) who are below or equal mass index (BMI, kg/m2) 85th percentile were retrospectively reviewed. Height, weight, waist circumference, blood pressure, serum lipid profiles, fasting plasma glucose insulin measured. Body fat...
Abstract Objective: The aim of this study is to evaluate the effect body mass index (BMI) on peak growth hormone (GH) response after GH stimulation test in children with short stature. Methods: Data was obtained from retrospective review medical records who visited pediatric endocrinology at St. Vincent hospital catholic university for stature January 2010 June 2019. We studied 115 (aged 3-17 years old) whose height less than 3percentile one’s age and sex underwent {GH deficiency (GHD) = 47,...
이 연구는 민속학적, 문화론적 접근을 통해 경북 칠곡군 A아파트 경로당에서 운영되는 노인 치매 예방 프로그램 참여 활동의 실태를 현지조사하여 분석하고, 오늘날 노인의 여가문화로서 프로그램이 가진 여가문화적 성격을 고찰한 것이다. 노인들의 삶과 일상생활의 맥락에서 활동이 어떤 의미가 있을지에 대해 살펴보았다.BR 활동에서 수강자들은 지자체에 의해 수강자들이 동원된 측면이 있다는 점, 지자체가 기획한 프로그램이라는 점에서 타율적이고 수동적인 모습을 보여주었다. 그럼에도 프로그램을 예방보다 놀이를 즐기거나, 운동을 하거나 지식을 습득하는 경향이 알찬 여가 시간을 보낼 수 있다고 인식한다는 자기개발 혹은 자아실현 등의 경험을 한다고 생각하는 ‘진지한 여가’활동으로 평가될 수도 있다. 따라서 전통적인 자발적 여가문화와 확연히 구별된다.BR 수강자들의 여가양상을 살펴볼 때 그들이 프로그램에 참여하는 이유는 다음과 같다. 프로그램은 이미 만들어진 참여만하는 것이기 때문에 굳이 여가활동에...