A5028428357- Chemical Synthesis and Reactions
- Polyoxometalates: Synthesis and Applications
- Catalysis for Biomass Conversion
- Oxidative Organic Chemistry Reactions
- Insect Pest Control Strategies
- Molecular spectroscopy and chirality
- Catalysis and Hydrodesulfurization Studies
- Asymmetric Synthesis and Catalysis
- Biofuel production and bioconversion
- Soil Carbon and Nitrogen Dynamics
- Carbohydrate Chemistry and Synthesis
- Isotope Analysis in Ecology
- Weed Control and Herbicide Applications
- Axial and Atropisomeric Chirality Synthesis
- biodegradable polymer synthesis and properties
- Inorganic and Organometallic Chemistry
- Drug Solubulity and Delivery Systems
- Microbial Natural Products and Biosynthesis
- Pesticide Residue Analysis and Safety
- Piperaceae Chemical and Biological Studies
- Lignin and Wood Chemistry
- Plant Parasitism and Resistance
- Crystallography and molecular interactions
- Synthetic Organic Chemistry Methods
- Mesoporous Materials and Catalysis
Universidade Federal de Viçosa
2012-2023
Division of Chemistry
2017-2020
State University of Norte Fluminense
2020
Me-β-cyclodextrin (Me-βCD) and HP-β-cyclodextrin (HP-βCD) inclusion complexes with isoniazid (INH) were prepared the aim of modulating physicochemical biopharmaceutical properties guest molecule, a well-known antibuberculosis drug. The architectures initially proposed according to NMR data Job plot ROESY followed by density functional theory (DFT) calculations (1)H spectra using PBE1PBE 6-31G(d,p) basis set, including water solvent effect polarizable continuum model (PCM), for various modes,...
Fatty acids (FA) are key ingredients in formulating numerous high-value chemicals.
A new and mild route of furfural acetalization with various alkyl alcohols catalyzed by cheap simple SnCl<sub>2</sub> has been developed.
Phthalides are frequently found in naturally occurring substances and exhibit a broad spectrum of biological activities. In the search for compounds with insecticidal activity, phthalides have been used as versatile building blocks syntheses novel potential agrochemicals. our work, Diels-Alder reaction between furan-2(5H)-one cyclopentadiene was successfully to obtain (3aR,4S,7R,7aS)-3a,4,7,7a-tetrahydro-4,7-methanoisobenzofuran-1(3H)-one...
In this work, we describe a new one-pot synthesis route of valuable linalool oxidation derivatives (i.e., 2-(5-methyl-5-vinyltetrahydrofuran-2-yl propan-2-ol) (1a)), 2,2,6-trimethyl-6-vinyltetrahydro-2H-pyran-3-ol (1b) and diepoxide (1c), using green oxidant hydrogen peroxide) under mild conditions room temperature). Lacunar Keggin heteropolyacid salts were the catalysts investigated in reaction. Among them, Na7PW11O39 was most active selective toward products. All characterized by FT-IR,...
In this work, we describe the use of iron (III) silicotungstate as a catalyst for synthesis solketal, fuel bioadditive, from glycerol and acetone. A high yield solketal was achieved in acetalization with acetone at room temperature short reaction time (ca. 1 h). Among various metal silicotungstates (i.e., Fe4/3SiW12O40, Cu2SiW12O40, Al4/3SiW12O40, Co2SiW12O40, Ni2SiW12O40), most active (>99%, conversion) highly selective (98%) toward formation solketal. Effects main parameters (e.g., to...
Abstract Phtalides are secondary metabolites found in several fungi with a wide range of biological activities. A novel phthalide analog was synthesized by Diels–Alder reaction between cyclopentadiene and 3,4‐dichlorofuran‐2(5 H )‐one. Quantum mechanical calculations were used conjunction the spectrometric methods to determine structure title compound. The calculated NMR chemical shifts for eight candidate pairs enantiomers compared experimental applying DP4 probability mean absolute errors...
In this study, the insecticide potential of eight phthalides derived from furan-2(5H)-one was evaluated against Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) larvae. The potency most active and susceptibility six different T. populations to these compounds were determined. toxicity molecules two non-target species (Solenopsis saevissima Smith Tetragonisca angustula Latreille) also evaluated. Two (3 4) presented absoluta. Phthalide 4 as toxic piperine (positive control) both exhibited...
Ten 4,7-methanoisobenzofuran-1(3H)-ones were synthesized and their insecticidal activities against the insect pest Diaphania hyalinata evaluated.The most active substances have been selected from initial screening to find dose kill 50 (LD ) 90% 90 of melonworm.Time-mortality curves three formulations at LD concentration made D. hyalinata.From time-mortality we found that formulation (3aR,4R,5S,6S,7S,7aS)-and (3aS,4S,5R,6R,7R,7aR)-5,6-dichlorohexahydro-4,7methanoisobenzofuran-1(3H)-one +...
Abstract Isobenzofuranones are known for their wide range of biological activities such as fungicide, insecticide, and anticancer. The search novel bioactive compounds was performed by reaction epoxide 2 with methanol, ethanol, propan‐1‐ol, propan‐2‐ol, butan‐1‐ol. mechanism the stereoselective stereospecific opening methanol reasoned calculating transition states two putative structures ( rac )‐3a )‐3b. compound is kinetic product inferred from lower energies its state (TS1). 1 H 13 C...
Drosophila suzukii, an invasive insect pest, poses a significant threat to various fruit crops. The use of broad-spectrum insecticides control this pest can reduce the effectiveness biological agents, such as parasitoid Trichopria anastrephae. Here, we evaluated toxicity newly synthesized lactone derivatives on D. suzukii and their selectivity towards T. We used in silico approaches identify potential targets from most promising molecules nervous system understand differences...
Given the weed resistance to various herbicides with different mechanisms of action, search for new compounds that are more effective and exhibit low levels impact other species in nature has been imperative field agriculture. For this purpose, 16 phthalides, furan-2(5H)-one were synthetized evaluated their effectiveness as seeds Sorghum bicolor (sorghum), Cucumis sativus (cucumber), Allium cepa (onion). Furthermore, a preliminary silico study was carried out identify enzyme target most...
An efficient and Brønsted acid-free route to synthesize monoterpene ethers was developed using SnBr2 as inexpensive commercially affordable catalyst. This process consists of the synthesis α-terpinyl alkyl in SnBr2-catalyzed reactions β-pinene with alcohols. The catalytic activity various tin(II) salts assessed compared that other homogeneous Lewis acids, etherification methyl alcohol. most active selective catalyst toward ether. Tin(II) bromide is a water tolerant acid, which emerges an...