- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Pulmonary Hypertension Research and Treatments
- Hemodynamic Monitoring and Therapy
- Cardiovascular Function and Risk Factors
- Muscle and Compartmental Disorders
- Electrolyte and hormonal disorders
- Vibrio bacteria research studies
- Ultrasound in Clinical Applications
- Hematopoietic Stem Cell Transplantation
- Eosinophilic Disorders and Syndromes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Drug-Induced Adverse Reactions
- Viral Infections and Immunology Research
- Cardiac Valve Diseases and Treatments
- Bacterial biofilms and quorum sensing
- Pneumocystis jirovecii pneumonia detection and treatment
- Hemoglobinopathies and Related Disorders
- Anesthesia and Sedative Agents
- Antibiotic Resistance in Bacteria
- Cardiac Imaging and Diagnostics
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
Prince of Songkla University
2015-2024
McGill University Health Centre
2020-2024
Royal Victoria Hospital
2022-2024
McGill University
2021-2023
Royal Victoria Regional Health Centre
2022
University of Toronto
2022
Rationale: The inspiratory rise in transpulmonary pressure during mechanical ventilation increases right ventricular (RV) afterload. One mechanism is that when Palv exceeds left atrial pressure, West zone 1 or 2 (non-zone 3) conditions develop, and becomes the downstream opposing RV ejection. Vt at which this impact on ventricle hemodynamically evident not well established. Objectives: To determine magnitude of afterload prevalence significant non-zone 3 inspiration across range currently...
Biofilm formation is an important virulence factor of Acinetobacter baumannii. Here, we examined the biofilm archived A. baumannii causing ventilator-associated pneumonia (VAP).
Right ventricular (RV) dysfunction is a commonly considered cause of low cardiac output in critically ill patients. Its management can be difficult and requires an understanding how the RV limits output. We explain that stroke caught between passive elastance walls during diastolic filling active produced by systole. These two elastances limit volume consequently left volume. emphasize use term "RV limitation" argue limitation primary pathophysiological process which causes hemodynamic...
Multisystem inflammatory syndrome (MIS) associated with severe acute respiratory coronavirus-2 (SARS-CoV-2) infection is a life-threatening condition first described in children (MIS-C). It characterized by hyperinflammatory state that involves the cardiovascular, gastrointestinal, dermatologic, and neurologic systems without system involvement. Myocarditis one of cardiovascular presentations MIS might be complicated cardiogenic shock. There are few case reports describing SARS-CoV-2-related...
OBJECTIVES: Implantation of venovenous extracorporeal membrane oxygenation as an alternative to invasive mechanical ventilation, “awake approach,” may facilitate a lung- and diaphragm-protective ventilatory strategies without the associated harms endotracheal intubation, positive pressure continuous sedation. This report presents characteristics outcomes patients treated with awake approach. DESIGN: Retrospective case series. SETTING: Monocenter study. PATIENTS: Severe acute respiratory...
Rhabdomyolysis is a condition that results in the release of mainly creatine kinase (CK) and myoglobin from breakdown myocytes. Myoglobin has been known to cause renal failure (RF) CK level routinely used as an indicator. A >5,000 U/l was found be associated with risk RF [1]. However, data are lacking on predict RF, especially general trauma patients. The purpose this study determine initial predicts markedly elevated characteristics patients CK.
Extracorporeal membrane oxygenation (ECMO) is a treatment option considered for acute respiratory distress syndrome (ARDS) patients who are refractory to conventional treatments. However, with ECMO has not shown significant reduction of mortality which may be due inappropriate selection criteria. Thus, we aim evaluate the outcomes treated in our center and determine an optimal cutoff level Respiratory Survival Prediction (RESP) score case selection. This was retrospective case-control study...
This case report describes a patient with Beta-thalassemia/hemoglobin E that developed Vibrio cholerae septicemia, leading to refractory septic shock maximum norepinephrine equivalent dose of 1.84 µg/kg/min and multi-organ failure. As the remained in despite receiving proper antibiotics organ support for 48 hours, adjunctive therapy including, HA330 hemoperfusion, was initiated. Shock reversal significant reduction inflammatory cytokines were achieved after two intervention sessions. The...
"Getting SILI between Two Extracorporeal Membrane Oxygenation Runs." Annals of the American Thoracic Society, 18(1), pp. 167–171
Management of hematopoietic stem cell transplant complicated by respiratory failure has been facilitated the use extracorporeal membrane oxygenation as a bridge to curative chemotherapeutic options. This is first report transplantation on in adult population.A 28-year-old woman diagnosed with idiopathic aplastic anemia acute distress syndrome secondary pneumonia required venovenous supplement and ventilation. She received while she was support.Delivery through circuit successful described...
Klippel-Trenaunay syndrome (KTS) is a rare, vascular malformation. The major clinical presentation an overgrowth involving the extremities. diagnosis of KTS was based on imaging study, which revealed malformations. author’s report 36-year Thai man with; hypertrophy right lower extremity, whilst having suffered from two-months bloody defecation. magnetic resonance showed venous malformations with soft tissue affected limb, genitalia and rectum. patient diagnosed with: accompanied by...
Abstract Purpose Reduction of right ventricular (RV) function after cardiac surgery has been shown to impact outcomes. Conventional indices for dysfunction are validated using transthoracic echocardiogram (TTE) which limited use compared transesophageal (TEE) in the perioperative settings. The aim this study was assess agreement RV systolic assessment with TEE TTE and association echocardiographic parameter hemodynamic dysfunction. Method This a single center prospective observational an...