Zacharoula Angelopoulou

ORCID: 0000-0002-0860-4461
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About
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Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hemodynamic Monitoring and Therapy
  • Sepsis Diagnosis and Treatment
  • Acute Ischemic Stroke Management
  • Heart Failure Treatment and Management
  • Emergency and Acute Care Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Coronary Interventions and Diagnostics
  • Cardiac and Coronary Surgery Techniques
  • Cardiac Arrest and Resuscitation

University of Thessaly
2021-2023

Critical emergency medicine is the medical field concerned with management of critically ill patients in department (ED). Increased ED stay due to intensive care unit (ICU) overcrowding has a negative impact on patient and outcome. It been proposed that implementation critical services can negate this effect. Two main Emergency Medicine models have proposed, "resource intensivist" "ED-ICU" models. The resource intensivist model based constant presence an traditional setting, while ED-ICU...

10.4266/acc.2020.00521 article EN cc-by-nc Acute and Critical Care 2021-01-28

It remains unknown whether chronic systemic inflammation is associated with impaired microvascular perfusion during surgery. We evaluated the association between preoperative basal inflammatory state, measured by plasma soluble urokinase-type plasminogen activator receptor (suPAR) levels, and intraoperative sublingual microcirculatory variables in patients undergoing major non-cardiac Plasma suPAR levels were determined 100 surgery using suPARnostic® quick triage lateral flow assay. assessed...

10.3390/jcm11123326 article EN Journal of Clinical Medicine 2022-06-10

Abstract Objective To test the hypothesis that there is an association between mean arterial pressure (MAP) and sublingual perfusion during major surgery, perhaps identifiable harm threshold. Methods This post hoc analysis of a prospective cohort included patients who had elective non‐cardiac surgery with duration ≥2 h under general anesthesia. We assessed microcirculation every 30 min using SDF+ imaging determined De Backer score, Consensus Proportion Perfused Vessels (Consensus PPV), PPV...

10.1111/micc.12804 article EN cc-by-nc-nd Microcirculation 2023-03-11

The calculated plasma volume status (cPVS) was validated as a surrogate of intravascular filling. aim this study is to assess the cPVS in relation sublingual perfusion and organ injury.Pre- postoperative were obtained by determining actual ideal levels surgical patients. microcirculation assessed using SDF imaging, we determined De Backer score, Consensus Proportion Perfused Vessels (Consensus PPV), PPV (small). Our primary outcome assessment distribution its association with intraoperative...

10.3390/jpm13071085 article EN Journal of Personalized Medicine 2023-06-30

ABSTRACT Background Patients undergoing major surgery are often at risk of developing postoperative complications. We investigated whether the inflammatory biomarker suPAR can aid in identifying patients high for complications, morbidity, and mortality. Methods In this prospective observational study ( ClinicalTrials.gov identifier: NCT03851965 ), peripheral venous blood was collected from consecutive adult scheduled non-cardiac with expected duration ≥2 hours under general anesthesia....

10.1101/2021.05.04.21256448 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-05-04

ABSTRACT INTRODUCTION The plasma suPAR level has previously been associated with postoperative complications and shown to be an independent predictor of coronary microvascular function flow reserve. We investigated the association between preoperative levels intraoperative sublingual perfusion in patients undergoing elective major non-cardiac surgery. Methods This study included 100 surgery February 2019 September 2020. primary objective was investigate De Backer score, Consensus Proportion...

10.1101/2021.07.03.21259960 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-07-05
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