- Cancer Immunotherapy and Biomarkers
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- Sirtuins and Resveratrol in Medicine
- Autophagy in Disease and Therapy
- Immune cells in cancer
- Cancer, Stress, Anesthesia, and Immune Response
- Coenzyme Q10 studies and effects
- Calcium signaling and nucleotide metabolism
- Retinal Imaging and Analysis
- CAR-T cell therapy research
- Congenital Diaphragmatic Hernia Studies
- Pancreatic and Hepatic Oncology Research
- Glycosylation and Glycoproteins Research
- Occupational and environmental lung diseases
- Retinal Diseases and Treatments
- Retinal Development and Disorders
- Nanoparticle-Based Drug Delivery
- Viral Infections and Outbreaks Research
- Meta-analysis and systematic reviews
- Genetic factors in colorectal cancer
- SARS-CoV-2 and COVID-19 Research
- Renal cell carcinoma treatment
- Toxin Mechanisms and Immunotoxins
- Bladder and Urothelial Cancer Treatments
Universal Scientific Education and Research Network
2020-2024
Research Network (United States)
2023-2024
Tehran University of Medical Sciences
2020-2023
Children's Medical Center
2020-2023
Northwestern University
2023
Renal Research Institute
2023
Abstract Background and Aims Critical appraisal or risk of bias assessment is a fundamental part systematic reviews that clarifies the degree to which included research articles are qualified reliable. Version 2 Cochrane tool for assessing in randomized trials (RoB 2), updated version first tool, was released 2019. Here, we have compared these two versions tools highlighted pros cons RoB 2. Methods Statistical analysis methodology not applicable this article as no new data were created...
Sirtuins (SIRT) exhibit deacetylation or ADP-ribosyltransferase activity and regulate a wide range of cellular processes in the nucleus, mitochondria, cytoplasm. The role only sirtuin that resides cytoplasm, SIRT2, development ischemic injury cardiac hypertrophy is not known. In this paper, we show hearts mice with deletion Sirt2 (Sirt2-/-) display improved function after ischemia-reperfusion (I/R) pressure overload (PO), suggesting SIRT2 exerts maladaptive effects heart response to stress....
There is a need for rapid, accurate, less-invasive approach to distinguishing malignant from benign pleural effusions. We investigated the diagnostic value of five tumor markers in exudative effusions.By immunochemiluminescence assay, we measured concentrations markers. used receiver operating characteristic curve analysis assess their values.A total 281 patients were enrolled. All significantly higher effusions than ones. The area under carcinoembryonic antigen (CEA), carbohydrate (CA)...
ABSTRACT Sirtuins (SIRT) exhibit deacetylation or ADP-ribosyltransferase activity and regulate a wide range of cellular processes in the nucleus, mitochondria cytoplasm. The role only sirtuin that resides cytoplasm, SIRT2, development heart failure (HF) cardiac hypertrophy is not known. In this paper, we show hearts mice with deletion Sirt2 ( -/- ) display improved function after ischemia-reperfusion (I/R) pressure overload (PO), suggesting SIRT2 exerts maladaptive effects response to...
Diabetic retinopathy (DR), as one of the main complications diabetes, is among leading causes blindness and visual impairment worldwide.Current clinical therapies include photocoagulation, vitrectomy, anti-vascular endothelial growth factor (VEGF) therapies. Bevacizumab ranibizumab are two monoclonal antibodies (mAbs) inhibiting angiogenesis. Intravitreal bevacizumab can decrease rate retinal thickness, improve acuity whether monotherapy or combined with other treatments. They increase...