A5051789675- Nanoparticle-Based Drug Delivery
- Protein Interaction Studies and Fluorescence Analysis
- Recycling and Waste Management Techniques
- Silk-based biomaterials and applications
- Hemoglobin structure and function
- Microplastics and Plastic Pollution
- Graphene and Nanomaterials Applications
- Advanced Proteomics Techniques and Applications
- Bipolar Disorder and Treatment
- Phytochemicals and Antioxidant Activities
- Cell Adhesion Molecules Research
- Plant-Microbe Interactions and Immunity
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dyeing and Modifying Textile Fibers
- Plant Virus Research Studies
- Horticultural and Viticultural Research
- Gastric Cancer Management and Outcomes
- PI3K/AKT/mTOR signaling in cancer
- Bone health and treatments
- Cholesterol and Lipid Metabolism
- Wound Healing and Treatments
- Plant Disease Management Techniques
- Irrigation Practices and Water Management
- Transgenic Plants and Applications
- Antioxidant Activity and Oxidative Stress
Nantong University
2024
Chongqing University
2020-2023
Chongqing University of Science and Technology
2018
Corvallis Environmental Center
2001
Albumin is derived from human or animal blood, and its ability to bind a large number of endogenous exogenous biomolecules makes it an ideal drug carrier. As result, albumin-based delivery systems are increasingly being studied. With these in mind, detailed studies the transport mechanism carriers particularly important. albumin receptors, glycoprotein 60 (GP60) secreted protein acidic rich cysteine (SPARC) play crucial role carriers. GP60 expressed on vascular endothelial cells enables...
Albumin is derived from plasma and it the most abundant protein in plasma, which an ideal material for preparation of nanoparticles because its good biocompatibility, noncytotoxicity, nonimmunogenicity, biodegradability, so on. Besides, albumin can enhance targeting drugs, reduce toxicity free water solubility hydrophobic etc. Drug delivery systems based on are widely used medical field. At present, main methods preparing desolvation, self-assembly, thermal gelation, spray-drying, double...
H uman s erum a lbumin (HSA) is highly water-soluble protein with 67% alpha-helix content and three distinct domains (I, II, III). HSA offers great promise in drug delivery enhanced permeability retention effect. But it hindered by denaturation during entrapment or conjugation that result cellular transport pathways reduction of biological activities. Here we report using design approach named r everse- QTY (rQTY) code to convert specific hydrophilic alpha-helices hydrophobic alpha-helices....
Infectious wounds have become serious challenges for both treatment and management in clinical practice, so development of new antibiotics has been considered an increasingly difficult task. Here, we report the design synthesis keratin 31 (K31)-peptide glycine-leucine-amide (PGLa) photopolymerized hydrogels to rescue antibiotic activity infectious wound healing promotion. K31-PGLa displayed outstanding synergistic effect with commercial against drug-resistant bacteria by down-regulating...
Although keratins are robust in nature, hydrogels producing their extracts exhibit poor mechanical properties due to the complicated composition and ineffective self-assembly. Here we report a bioinspired strategy fabricate keratin based on mechanism study through recombinant proteins. Homotypic heterotypic self-assembly of selected type I II different combinations was conducted identify crucial domain structures for process, kinetics, relationship with strength hydrogels. Segments best...
Trichosanlhes kirilowii Maxim seed oil (TSO) is rich in conjugated linolenic acids, and the flavonoids (FLA) combined with n-3 fatty acids can effectively change plasma antioxidant capacity. Hyperlipidemia oxidative stress are one of most important risk factors for cardiovascular disease. This study aims to evaluate effect TSO, FLA, TSO FLA (TSOFLA) intake on hyperlipemia mice. TSOFLA administration resulted a significant decline serum levels total cholesterol, triglycerides, low density...
Botrytis cinerea is one of the most destructive fungal pathogens causing tremendous losses in fresh fruit or vegetables. 3-Methylthio-1-propanol (3-MP) a naturally occurring food-borne sulfide, which mainly used to increase flavor food. However, potential application 3-MP postharvest phase manage diseases has not been explored. In this study, antifungal activity against B. was evaluated, and possible mechanism involved vitro treatment could effectively inhibit mycelial growth, spore...
Apyrases belong to the ATPase family of enzymes that hydrolyze phosphoanhydride bonds nucleoside tri- and di-phosphates. These differ markedly from other phosphohydrolases due their high specific activity, broad divalent cation requirement, nucleotide substrate specificity, insensitivity various inhibitors. In past 30 years, apyrases have been frequently studied in mammals. comparison, research plants has received little attention, despite growth being closely related apyrases. this review,...
IntroductionGastric ulcer is one of the most common diseases affecting global human health [1,2].But effective diagnosis and repair gastric remain a challenge in clinic.Endoscopy was frequently used for diagnosis, which also to assist biomaterial-mediated therapy [3].However, complications endoscopy have been found [4].Here, keratin conjugated acryloyl-6aminocaproic acid nanoparticles (K-co-A6ACA NPs) entrapped with IR783 were fabricated early treatment mice without guidance.Human hair could...