Laura Bognár

ORCID: 0000-0002-0885-0419
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About
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Research Areas
  • Gastroesophageal reflux and treatments
  • Esophageal and GI Pathology
  • Dysphagia Assessment and Management
  • Pancreatic and Hepatic Oncology Research
  • Medical Imaging Techniques and Applications
  • Esophageal Cancer Research and Treatment
  • RNA modifications and cancer
  • Reconstructive Surgery and Microvascular Techniques
  • Cardiac Ischemia and Reperfusion
  • Cancer, Hypoxia, and Metabolism
  • Congenital Diaphragmatic Hernia Studies
  • Gastric Cancer Management and Outcomes
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cancer Research and Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Eosinophilic Esophagitis

University of Pecs
2015-2019

The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also compare the heat shock proteins (Hsp) 90, 27 16.2 growth hormone-releasing hormone receptor (GHRH-R) expression patterns pre-treatment tumor biopsies status response.Pre-treatment 74 locally advanced processed retrospectively. presence was detected by chromogenic situ hybridization. Hsp GHRH-R expressions...

10.1186/s13027-018-0210-9 article EN cc-by Infectious Agents and Cancer 2018-11-28

Ischemia-reperfusion injury may lead to insufficient microcirculation and results in partial flap loss during the free surgeries.This study aimed investigate effect of trimetazidine (TMZ) on oxidative stress, inflammation histopathological changes, using epigastric skin model rats.40 male Wistar rats were used, that divided into four groups. Control group, non-treated ischemic (I/R)-group two treated groups (preischemically, postischemically) established. To create ischemia flap, superficial...

10.3233/ch-170335 article EN Clinical Hemorheology and Microcirculation 2018-04-13

Absztrakt A belgyógyászati módszerekkel panasz- és tünetmentessé nem tehető gastrooesophagealis refluxbetegségben szenvedő betegek kezelésére bevált módszer a laparoszkópos antireflux-sebészet. Gyakorlatot szerzett sebészek nagy biztonsággal végzik műtétet, mégis fellépnek intraoperativ, korai postoperativ késői szövődmények, amelyek reoperációt tehetnek szükségessé. Pécsi Tudományegyetem Sebészeti Klinikáján 1998 2015 között 407 antirefluxműtétet végeztünk. periódust két szakaszra...

10.1556/1046.69.2016.3.1 article HU Magyar Sebészet (Hungarian Journal of Surgery) 2016-09-01

Absztrakt Esetismertetés: A szerzők egy 68 éves beteg esetét ismertetik, akinél hálóbeültetéses hiatusplasztikával kiegészített antirefluxműtétet követően négy hónappal dysphagiás panaszok jelentkeztek. Az elvégzett vizsgálatok a háló részleges nyelőcsőbe penetrálását igazolták. Halasztott sürgősséggel végzett műtét során thoracolaparotomiás feltárásból hálót eltávolították, nyelőcsövön észlelt hosszanti lyuk és alatta rövid szűkület miatt distalis nyelőcső- proximalis gyomorresectiót...

10.1556/1046.68.2015.4.4 article HU Magyar Sebészet (Hungarian Journal of Surgery) 2015-08-01

Achalasia is a motility disorder of the esophagus characterized by defective peristaltic activity esophageal body and impaired relaxation lower sphincter due to degeneration inhibitory neurons in myenteric plexus wall. The histopathological pathophysiological changes achalasia have been well described. However, exact etiological factors leading disease still remain unclear. Currently, believed be multifactorial disease, involving both extrinsic intrinsic factors. Based on our experience...

10.2147/tcrm.s152429 article EN cc-by-nc Therapeutics and Clinical Risk Management 2017-12-01

Achalasia is a primary esophageal motility disorder of unknown etiology, characterized by aperistalsis the body and impaired lower sphincter (LES) relaxation. Available data suggest that disease multifactorial, but exact initiating factors may play role in development remain unclear. Case presentation: We report case 65 year-old woman who had typical reflux symptoms with heartburn regurgitation for about seven years. During year before her admission to our clinic resolved dysphagia...

10.4172/2161-069x.1000432 article EN cc-by Journal of Gastrointestinal & Digestive System 2016-01-01

Achalasia is a primary esophageal motility disorder of unknown etiology, characterized by aperistalsis the body and impaired lower sphincter (LES) relaxation. However achalasia best disorder, its pathogenesis still not entirely clarified. Available data suggest that disease multifactorial, involving hereditary, autoimmune environmental factors, such as viral infections, but exact initiating factors may play role in development remain unclear. Our hypothesis one possible initial insult leads...

10.1016/j.nhccr.2017.06.154 article EN cc-by-nc-nd European Journal of Molecular & Clinical Medicine 2017-09-07

Abstract Background The aims of this study were to evaluate whether HPV infection has a prognostic role in patients with esophageal squamous cell carcinoma who underwent oncological treatment and also correlate the heat shock proteins (Hsp) 90, 27 16.2 growth hormone-releasing hormone receptor (GHRH-R) expression patterns pre-treatment tumor biopsies status response. Methods Pre-treatment 74 locally advanced processed retrospectively. presence was detected by chromogenic situ hybridization....

10.1093/dote/doy089.ps02.042 article EN Diseases of the Esophagus 2018-09-01
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