A5102013420- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
Guangdong Academy of Medical Sciences
2009-2025
South China University of Technology
2024-2025
Southern Medical University
2024-2025
Guangdong Provincial People's Hospital
2024-2025
Guangdong General Hospital
2009-2021
This study aimed to explore the novel biomarkers for immune checkpoint inhibitor (ICI) responses in non-small cell lung cancer (NSCLC) by integrating genomic profiling, tumor mutational burden (TMB), and expression of programmed death receptor 1 ligand (PD-L1).Tumor blood samples from 637 Chinese patients with NSCLC were collected targeted panel sequencing. Genomic alterations, including single nucleotide variations, insertions/deletions, copy number gene rearrangements, assessed TMB was...