Marta Kepinská

ORCID: 0000-0002-0935-5663
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Trace Elements in Health
  • Advanced biosensing and bioanalysis techniques
  • Nanocluster Synthesis and Applications
  • Advanced Nanomaterials in Catalysis
  • Quantum Dots Synthesis And Properties
  • Graphene and Nanomaterials Applications
  • Nanoparticle-Based Drug Delivery
  • Nitric Oxide and Endothelin Effects
  • Heavy Metal Exposure and Toxicity
  • Medicinal Plants and Neuroprotection
  • Diet, Metabolism, and Disease
  • Essential Oils and Antimicrobial Activity
  • Animal Disease Management and Epidemiology
  • Nanoplatforms for cancer theranostics
  • Renin-Angiotensin System Studies
  • Fullerene Chemistry and Applications
  • Vitamin C and Antioxidants Research
  • Selenium in Biological Systems
  • Carbon and Quantum Dots Applications
  • Iron Metabolism and Disorders
  • Paraoxonase enzyme and polymorphisms
  • RNA Interference and Gene Delivery
  • Adipokines, Inflammation, and Metabolic Diseases
  • Animal Diversity and Health Studies

Wroclaw Medical University
2016-2025

National Institute of Standards and Technology
2023

Université de Lorraine
2023

University of Veterinary Sciences Brno
2020

Mendel University in Brno
2020

Oxidative stress is proven to increase cardiovascular risk and diminish healthy life expectancy. Sleep bruxism (SB) a prevalent masticatory muscle activity during sleep characterized by heterogeneous etiology inadequately recognized pathophysiology. Recent theories have proposed potential association between SB oxidative stress. The aim of the research was compare antioxidant status individuals with in contrast those without SB. A total 80 adults participated full-night polysomnography,...

10.1038/s41598-025-86833-y article EN cc-by-nc-nd Scientific Reports 2025-01-28

One approach for solving the problem of antibiotic resistance and bacterial persistence in biofilms is treatment with metals, including silver form nanoparticles (AgNPs). Green synthesis an environmentally friendly method to synthesize a broad spectrum unique properties that depend on plant extracts used. AgNPs antibacterial antibiofilm effects were obtained using green from Lagerstroemia indica (AgNPs_LI), Alstonia scholaris (AgNPs_AS), Aglaonema multifolium (AgNPs_AM). Nanoparticles...

10.3390/nano12132183 article EN cc-by Nanomaterials 2022-06-25

The ongoing COVID-19 pandemic has significantly limited social contacts, thus contributing to deepening isolation. Therefore, SARS-CoV-2 exerted on humanity not only a physical impact but also psychological one, often increasing the feeling of stress. long-term effects such state could include management depression, so our study aimed analyze groups medical students in different periods (at beginning pandemic, after half year one pandemic) order assess this situation coping with development...

10.3390/ijerph19010302 article EN International Journal of Environmental Research and Public Health 2021-12-28

AgNPs have attracted considerable attention in many applications including industrial use, and their antibacterial properties been widely investigated. Due to the green synthesis process employed, nanoparticle surface can be coated with molecules biologically important characteristics. It has reported that increased use of nanoparticles elevates risk release into environment. However, little is known about behaviour eco-environment. In this study, effect synthesized on germinated plants...

10.3390/nano9111550 article EN cc-by Nanomaterials 2019-10-31

Little is known about the contribution of each three superoxide dismutase isozymes (SODs) to total SOD activity in extracellular fluids. This study was aimed investigate alterations concentration/activity plasma, context sex, obesity, exposition cigarette smoke, and genotypic variability five selected single nucleotide polymorphisms (SNPs) genes SOD1, SOD2, SOD3. Men showed higher SOD1 concentration, lower SOD3 concentration antioxidative capacity (TAC) values. Intersexual observed copper,...

10.3390/ijms21145069 article EN International Journal of Molecular Sciences 2020-07-17

Sarcosine is an amino acid that formed by methylation of glycine and present in trace amounts the body. Increased sarcosine concentrations blood plasma urine are manifested sarcosinemia some other diseases such as prostate cancer. For this purpose, detection using nanomedicine approach was proposed. In study, we have prepared superparamagnetic iron oxide nanoparticles (SPIONs) with different modified surface area. Nanoparticles (NPs) were chitosan (CS), oxidase (SOX). SPIONs without any...

10.3390/ijms19123722 article EN International Journal of Molecular Sciences 2018-11-22

Abstract The clinical use of doxorubicin (DOX) is limited by dose‐related cardiomyopathy, which becomes more prevalent with increasing cumulative doses the drug. Complexes fullerene DOX were designed and studied using biophysical methods. ability to release from at different pHs was analyzed. It has been shown that size fullerene‐DOX complexes ∼280 nm. zeta potential for ‒30 mV, ‒8 conjugates ‒24 mV. Drug CE LIF detection. When separated in a pH 7.5 buffer, 43% all signals derived free DOX,...

10.1002/elps.201800148 article EN Electrophoresis 2018-06-22

The aim of this study was to obtain new, safe, and effective compounds with anticancer activity since cancer is still the leading cause mortality worldwide. rational design new based on introduction differentially substituted phenylpiperazines into 1,2-benzothiazine scaffold as a reference for structures recent topoisomerase II (Topo II) inhibitors such dexrazoxane XK-469. newly designed group derivatives synthesized tested healthy (MCF10A) (MCF7) cell lines, alone in combination doxorubicin...

10.3390/molecules29184282 article EN cc-by Molecules 2024-09-10

Silver nanoparticles are the most important in connection with antimicrobial effect.Nowadays, green synthesis of various types is rapid, effective and produce less toxic often specific properties.In our experiment we have developed described details silver synthesized chemically or by synthesis.Nine different were synthesized, three citrate method at pHs (8; 9; 10), four using gallic acid alkaline (10; 11), two tea coffee extracts, both pH 9. Characterisation was performed dynamic light...

10.1166/jnn.2019.15867 article EN Journal of Nanoscience and Nanotechnology 2018-12-02

The European Food Safety Authority recommends C. incanus as a natural source of antioxidants. Its activity is essentially determined by polyphenols, although specific compounds are not finally indicated. available plant material comes from different subspecies and locations, which can lead to differences in chemical composition potency. For this reason, we conducted detailed analysis the polyphenol content antioxidant 52 teas Turkey, Albania, Greece, unspecified regions. We focused special...

10.3390/antiox12030553 article EN cc-by Antioxidants 2023-02-22
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