A5026242877- Click Chemistry and Applications
- Cancer, Hypoxia, and Metabolism
- Advanced Proteomics Techniques and Applications
- Microbial Metabolic Engineering and Bioproduction
- Metabolomics and Mass Spectrometry Studies
- Biochemical and Molecular Research
Indian Institute of Science Education and Research, Bhopal
2022-2023
Indian Institute of Science Education and Research Pune
2022-2023
Choline is an essential nutrient for mammalian cells. Our understanding of the cellular functions choline and its metabolites, independent their roles as lipid metabolism intermediates, remains limited. In addition to fundamental physiology, this knowledge has implications cancer biology because elevated metabolite levels are a hallmark cancer. Here, we establish metabolite-interacting proteome by utilizing photocrosslinkable probe. To design probe, performed metabolic labeling experiments...
ABSTRACT Choline is an essential nutrient for mammalian cells. Our understanding of the cellular functions choline and its metabolites, independent their roles as lipid metabolism intermediates, remains limited. In addition to fundamental physiology, this knowledge has implications cancer biology because elevated metabolite levels are a hallmark cancer. Here, we establish metabolite-interacting proteome by utilizing photocrosslinkable probe. To design probe, performed metabolic labeling...