A5041813281- COVID-19 Clinical Research Studies
- COVID-19 Impact on Reproduction
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Pregnancy and Medication Impact
- Long-Term Effects of COVID-19
- Inflammation biomarkers and pathways
- Reproductive System and Pregnancy
- Immune Response and Inflammation
- SARS-CoV-2 and COVID-19 Research
- Immune Cell Function and Interaction
- Immune responses and vaccinations
- Immunodeficiency and Autoimmune Disorders
- Tuberculosis Research and Epidemiology
- IL-33, ST2, and ILC Pathways
- Eosinophilic Esophagitis
- Neonatal and Maternal Infections
- Phonocardiography and Auscultation Techniques
- Hemodynamic Monitoring and Therapy
Mexican Social Security Institute
2018-2023
Instituto Politécnico Nacional
2018-2023
Centro Medico Nacional Siglo XXI
2018-2023
Hospital de Especialidades
2018-2022
Abstract Acute systemic inflammation can lead to life-threatening organ dysfunction. In patients with sepsis, is triggered in response infection, but other patients, a inflammatory syndrome (SIRS) by non-infectious events. IL-6 major mediator of inflammation, including responses. homeostatic conditions, when engages its membrane-bound receptor on myeloid cells, it promotes pro-inflammatory cytokine production, phagocytosis, and cell migration. However, under non-physiologic such as SIRS...
Sepsis, one of the leading causes death in intensive care units, is caused by a dysregulated host response to infection that leads life-threatening organ dysfunction. The proinflammatory and anti-inflammatory responses activated infecting microorganism become systemic, sustained induces state immunosuppression characterized decreased expression HLA-DR on monocytes, T cell apoptosis, reduced production TNF-α monocytes macrophages TLR ligands. Innate lymphoid cells (ILCs) are lymphocytes lack...
Sepsis is a life-threatening condition associated with failure of at least one organ in the presence infection. Along SIRS, acute systemic inflammatory syndrome without documented infection, sepsis represents main health problem intensive care units around world. Hypercytokinemia and overexpression activation-markers on leukocytes are frequently reported SIRS/sepsis. Leukocyte functions including antibody mediated-phagocytosis, pathogen recognition, migration appear to be disabled...
Current medical guidelines consider pregnant women with COVID-19 to be a high-risk group. Since physiological gestation downregulates the immunological response maintain “maternal-fetal tolerance”, SARS-CoV-2 infection may constitute potentially threatening condition both mother and fetus. To establish immune profile in COVID-19+ patients, cross-sectional study was conducted. Pregnant (P-COVID-19+; n = 15) were analyzed compared nonpregnant (NP-COVID-19+; or those pregnancy (P-COVID-19-;...
Most individuals infected with Mycobacterium tuberculosis (Mtb) have latent (TB), which can be diagnosed tests (such as the QuantiFERON-TB Gold test [QFT]) that detect production of IFN-γ by memory T cells in response to Mtb-specific antigens 6 kDa early secretory antigenic target EsxA (Rv3875) (ESAT-6), 10 culture filtrate antigen EsxB (Rv3874) (CFP-10), and Mtb 7.7 (Rv2654c) (TB7.7). However, immunological mechanisms determine if an individual will develop or active TB remain incompletely...
On January 30th, 2020, the WHO declared outbreak of COVID19, a disease due to new coronavirus called SARS-CoV-2. Certain comorbidities, symptoms and signs are characteristic COVID19 in general population pregnant women. However, women considered as high-risk group for COVID19. To know about frequency symptoms, presence lymphopenia, antibodies response SARS-CoV2 cytokine chemokine serum concentration, six with were studied at moment admission. The lower concentration CCL17 was detected...
The difficulty in predicting fatal outcomes patients with coronavirus disease 2019 (COVID-19) impacts the general morbidity and mortality due to severe acute respiratory syndrome-coronavirus 2 infection, as it wears out hospital services that care for these patients. Unfortunately, several of candidates prognostic biomarkers proposed, predictive power is compromised when have pre-existing comorbidities. A cohort 147 hospitalized COVID-19 was included a descriptive, observational,...
Abstract Current medical guidelines consider COVID-19 pregnant women a high-risk group. Physiological gestation down regulates the immunological response to maintain “maternal-fetal tolerance”; hence, SARS-CoV-2 infection constitutes potentially threatening condition both mother and fetus. To establish immune profile in COVID-19+ patients cross-sectional study was conducted. Leukocyte immunophenotype, mononuclear leukocyte polyclonal stimulus cytokine/chemokine serum concentration were...
Abstract Background The difficulty to predict fatal outcomes in COVID-19 patients, impacts the general morbidity and mortality due SARSCoV2 infection, as it wears out hospital services that care for these patients. Unfortunately, several of candidates prognostic biomarkers proposed, predictive power is compromised when patients have pre-existing co-morbidities. Methods A cohort one hundred forty-seven hospitalized severe COVID19 was included a descriptive, observational, single-center,...