- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Vascular anomalies and interventions
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Neurological disorders and treatments
- Kawasaki Disease and Coronary Complications
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Health and Disease Prevention
- Pneumothorax, Barotrauma, Emphysema
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Risk Factors
- Pleural and Pulmonary Diseases
- Hemodynamic Monitoring and Therapy
- Cardiovascular Issues in Pregnancy
- Cardiovascular and Diving-Related Complications
- Advances in Oncology and Radiotherapy
Mount Sinai Hospital
2021-2024
Aga Khan University
2015-2024
Mount Sinai Hospital
2024
Johns Hopkins University
2024
Icahn School of Medicine at Mount Sinai
2021-2023
Aga Khan University Hospital
2018-2021
Aga Khan University Hospital Nairobi
2016-2018
Ziauddin University
2018
University of Arkansas for Medical Sciences
2018
Abstract BACKGROUND Uncontrolled blood pressure (BP) is a leading risk factor for death and disability in South Asia. We aimed to determine the cross-country variation, factors associated with uncontrolled BP among adults treated hypertension rural METHODS enrolled 1,718 individuals aged ≥40 years cross-sectional study from communities Bangladesh, Pakistan, Sri Lanka. Multivariable logistic regression model was used (systolic ≥140 mmHg or diastolic ≥90 mmHg). RESULTS Among hypertensive...
Anomalous coronary arteries are congenital anomalies characterized by an abnormal location of the ostium and/or atypical vascular course. While most cases asymptomatic and remain undiagnosed, certain variants can be clinically significant, causing symptoms or even sudden cardiac death. A retro-aortic course artery is generally considered to benign, though rare instances have been reported cause myocardial ischemia. This detected on transthoracic echocardiogram (TTE) as a anomalous (RAC)...
BackgroundCOBRA-BPS (Control of Blood Pressure and Risk Attenuation-Bangladesh, Pakistan, Sri Lanka), a multi-component hypertension management programme that is led by community health workers, has been shown to be efficacious at reducing systolic blood pressure in rural communities Bangladesh, Lanka. In this study, we aimed assess the budget required scale up incremental cost-effectiveness ratios.MethodsIn cluster-randomised trial COBRA-BPS, individuals aged 40 years or older with who...
Our previous study showed that post-clinic blood pressure (BP) taken 15 min after a physician–patient encounter was the lowest reading in routine clinic. We aimed to validate this with 24 h Ambulatory Blood Pressure Monitoring (ABPM) readings. A cross-sectional conducted cardiology clinics at Aga Khan University, Pakistan. Hypertensive patients aged ≥ 18 years, or those referred for diagnosis of hypertension were included. Of 150 participants, 49% males. 76% all participants hypertensive....
COVID-19 pandemic has introduced us to a greater need of virtual learning platforms and resulted in less clinical exposure for fellows-in-training. Virtual simulator-based is not widely available LMIC. It imperative analyze feedback CV fellow-in-training regarding this mode before large scale implementation.This was an observational study conducted between July-August 2020. A multicentered survey conducted. Survey questionnaire disseminated FIT (fellow-in-training) via Google Forms. The...
There is lack of large data from South-Asian region on atrial fibrillation and it imperative that clinical presentation, prognostic factors, management pursued, outcomes are known for this part the world. Once collective evidence known, region-specific guidelines can be laid forward.To evaluate characteristics factors at a tertiary care center Pakistan.This was retrospective study conducted Pakistan. Period ranged July-December 2018. All hospitalized patients who were admitted with as...
Fainting is a common clinical presentation, with vagally mediated (neurocardiogenic) causes being the most for syncope presentation to emergency room, and hospital admissions. Classic teaching that upright posture prerequisite (VMS) in supine position has more sinister causes. We present five patients, three males two females, mean age of 44.4 (range 29–67) years, who presented VMS (sleep fainting). Four patients also had history classic syncope. Based on their features thorough...
The mechanism and severity of mitral valve (MV) regurgitation (MR) play a critical role in guiding treatment decisions. Transthoracic echocardiography (TTE) is the primary diagnostic modality for evaluating MV disease. Discordant findings on TTE can be further quantified through transesophageal (TEE). We describe case young woman with worsening exertional dyspnea who was found to have restricted posterior leaflet moderate severe eccentric MR TTE. TEE subsequently performed determine exact...
Dual left anterior descending (LAD) coronary artery is a rare anatomical variant with significant clinical implications. Recognizing this crucial for accurate diagnosis and effective management, particularly in the context of revascularization strategies. We present 71-year-old male history dyspnea on exertion baseline wall motion abnormality transthoracic stress echocardiography irreversible after exercise. Coronary computed tomography angiography revealed dual LAD system: The short (LAD1)...
Congenitally corrected transposition of the great arteries (CCTGA) is a rare congenital cardiac defect with atrioventricular and ventriculoarterial discordance which leads to heart failure limits patients' lifespan. We report case 70-year-old lady, from poor province in Pakistan, who presented for first time palpitations was diagnosed have CCTGA. She had moderate pulmonic valve stenosis protective against failure. six children all born via spontaneous vertex delivery her local village. This...
A handful of cases voluntary control left bundle branch block (LBBB) have been described in the literature. We report case a middle-aged man who was found to LBBB on baseline electrocardiogram (ECG) which disappeared coughing and then reappeared with same maneuver. Subsequent myocardial perfusion scan showed reduced count anteroseptal region likely attributed LBBB. It is possible that intermittent conduction changes may be due alteration vagal tone associated cough as reflected change PR...
Every third patient in the clinic is misdiagnosed due to white-coat phenomenon, necessitating needless and costly treatment. We aimed study hemodynamic response of physician's visit on hypertensive normotensive patients by investigating trend blood pressure (BP) before, during 15 min after physician-patient encounter.A descriptive, cross-sectional was conducted over a period 8 months cardiology clinics at Aga Khan University Hospital, Karachi. Both patients, aged ≥18 years, were recruited....