- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Genetic and phenotypic traits in livestock
- Cancer Treatment and Pharmacology
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Identification and Quantification in Food
- Pain Mechanisms and Treatments
- Animal Ecology and Behavior Studies
- Nanoparticle-Based Drug Delivery
- Congenital Heart Disease Studies
- Genetic Mapping and Diversity in Plants and Animals
- Cardiovascular Issues in Pregnancy
- MRI in cancer diagnosis
- Pharmacological Receptor Mechanisms and Effects
- Quantum Dots Synthesis And Properties
- Characterization and Applications of Magnetic Nanoparticles
- Environmental DNA in Biodiversity Studies
- Neuroscience and Neuropharmacology Research
Universidade do Porto
2007-2022
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2022
Instituto de Investigaciones Biomédicas Sols-Morreale
2018
Universidad Autónoma de Madrid
2018
University of Coimbra
2017
Noninvasive genetic approaches continue to improve studies in molecular ecology, conservation genetics and related disciplines such as forensics epidemiology. sampling allows without disturbing or even seeing the target individuals. Although noninvasive has been used for wildlife since 1990s, technological advances make among most rapidly advancing areas genetics. Here, we review recent how they allow us address important research management questions thanks improved techniques DNA...
Cross-breeding between wild and free-ranging domestic species is one of the main conservation problems for some threatened species. The situation wildcats (Felis silvestris silvestris) in Europe a good example this critical phenomenon. Extensive hybridization was described Hungary Scotland, contrasting with occasional interbreeding Italy Germany. First analyses Portugal revealed clear genetic differentiation cats; however, four hybrids were detected. Here, we extended approach to Iberian...
Abstract Severe climatic changes during the Pleistocene shaped distributions of temperate‐adapted species. These species survived glaciations in classical southern refuges with more temperate climates, as well western and eastern peripheral Alpine areas. We hypothesized that European wildcat ( Felis silvestris ) populations currently distributed Italy differentiated in, expanded from two distinct glacial refuges, located Apennines at periphery Alps. This hypothesis was tested by genotyping...
Extant populations of the European wildcat are fragmented across continent, likely consequence recent extirpations due to habitat loss and over-hunting. However, their underlying phylogeographic history has never been reconstructed. For testing hypothesis that survived Ice Age in Mediterranean refuges, we assayed genetic variation at 31 microsatellites 668 presumptive wildcats sampled 15 countries. Moreover, evaluate extent subspecies/population divergence identify eventual wild × domestic...
This work reports on highly fluorescent and superparamagnetic bimodal nanoparticles (BNPs) obtained by a simple efficient method as probes for fluorescence analysis and/or contrast agents MRI. These promising BNPs with small dimensions (ca. 17 nm) consist of iron oxide (SPIONs) covalently bound CdTe quantum dots 3 nm). The chemical structure the magnetic part is predominantly magnetite, minor goethite maghemite contributions, shown Mössbauer spectroscopy, which compatible x-ray diffraction...
Chemotherapy-induced neuropathy (CIN) is one of the most common complications cancer treatment with sensory dysfunctions which frequently include pain. The mechanisms underlying pain during CIN are starting to be uncovered. Neuroimaging allows identification brain circuitry involved in processing and modulation has recently been used unravel disruptions that by neuropathic present study evaluates effects paclitaxel, a cytostatic drug treatment, at neuronal function anterior cingulate cortex...