A5087450545- Glutathione Transferases and Polymorphisms
- Nutrition, Genetics, and Disease
- BRCA gene mutations in cancer
- Estrogen and related hormone effects
- DNA Repair Mechanisms
- Influenza Virus Research Studies
- Diet, Metabolism, and Disease
- Genomics, phytochemicals, and oxidative stress
- Epigenetics and DNA Methylation
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Medicinal Plant Research
- Carcinogens and Genotoxicity Assessment
- Diabetes and associated disorders
- Bone health and osteoporosis research
- Bone health and treatments
- Folate and B Vitamins Research
- Diverse Scientific Research Studies
- Smoking Behavior and Cessation
- Medicinal Plants and Neuroprotection
- biodegradable polymer synthesis and properties
- Nicotinic Acetylcholine Receptors Study
- Molecular Biology Techniques and Applications
- Pharmacogenetics and Drug Metabolism
- Food and Agricultural Sciences
Universidad Autónoma del Estado de Morelos
2015-2023
Universidad Nacional Autónoma de México
2011-2013
Breast cancer is associated to estrogen exposure. Allelic variants involved in metabolism might change the risk of developing this neoplasia. We examined potential association breast Mexican women with polymorphisms CYP1A1 rs1048943, CYP1B1 rs1056836, COMT rs4680, GSTP1 rs1695, GSTT1 null and GSTM1 which are pathway. This study included 150 cases controls. A significant was observed between, rs1048943 (OR = 1.95, C.I. 1.13-3.36) rs1695 2.39, 1.24-4.24) cancer. increased when were stratified...
Abstract Background and purpose Smoking is a major public health problem worldwide. Polymorphisms in CHRNA3 , CHRNA5 CHRNB4 receptors play critical role nicotine dependence, lung cancer (LC) risk, chronic obstructive pulmonary disease (COPD). This study characterized the rs1051730 rs16969968 polymorphisms Mexican population its association with LC, COPD. Methods The included 312 healthy individuals, 74 LC cases 117 COPD cases. Genotyping was performed using TaqMan probes, data were analyzed...
Aspergillus flavus affects fresh and dry fruit vegetable products, its toxic metabolites, namely aflatoxins, cause serious damage in humans. The objective of this research study was to evaluate the effect commercial natural products as well edible nanostructured chitosan coatings on development A. production aflatoxins vitro tomato. Treatments were follows: 1%, coating, Citrocover 1% (citrus seed extract), Resinadher 0.5% (pine resin mancozeb 2%, water. variables halo inhibition, spore...
Lung cancer is the leading cause of mortality in Mexico and worldwide. In past decade, there has been an increase number lung cases young people, which suggests important role for genetic background etiology this disease. study, we genetically characterized 16 polymorphisms 12 low penetrance genes (AhR, CYP1A1, CYP2E1, EPHX1, GSTM1, GSTT1, GSTPI, XRCC1, ERCC2, MGMT, CCND1 TP53) 382 healthy Mexican Mestizos as first step elucidating structure population identifying high risk individuals. All...
Background and Aims: Currently, treatments are being sought to improve the control of type II diabetes mellitus (T2DM), inulin has been shown be effective in reducing glucose levels other metabolic parameters. These effects on may associated with changes epigenetic modulation genes insulin pathway. Therefore, our objective is determine effect agave parameters INS IRS1 genes’ methylation T2DM patients. Methods: This was a longitudinal experimental study 67 Mexican participants who received an...
O6-Methylguanine-DNA methyltransferase (MGMT) is an enzyme that repairs the DNA damage caused by tobacco habit, and low activity of this has been associated with a risk lung cancer (LC). Our objective was to determine association promoter methylation rs12917 polymorphism MGMT formation bulky adducts LC in Mexican Mestizo population. In study are included 431 subjects. High-resolution melting analysis used levels. were determined 32P-postlabeling. results showed higher levels LC. The related...
The RANK/RANKL/OPG signaling is important in the regulation of bone turnover. aim present work was to analyze rs3018362 and rs12585014 polymorphisms RANK RANKL genes, as well risk factors postmenopausal women. Women with hip fracture, femoral neck osteoporosis controls (n = 646) were recruited. From these, 303 women who fulfill inclusion criteria genotyped using real-time PCR TaqMan probes. There no associations or fracture. When divided by age at menarche, GG genotype strongly associated...
<p>SARS-CoV-2 is the virus that causes COVID-19 disease, responsible for second pandemic of 21st century. This has caused a health emergency due to its rapid transmission and high mortality rate. The use disinfectants chemical origin increased considerably avoid contamination by SARS-CoV-2 but when used incorrectly they can pose risk. Citrus-based extracts have shown effectiveness in controlling development fungi bacteria in<em> vitro</em> <em>in situ</em>...