A5101862993- Parkinson's Disease Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Intracranial Aneurysms: Treatment and Complications
- Neurological disorders and treatments
- Advanced MRI Techniques and Applications
- Vascular Malformations Diagnosis and Treatment
- Transcranial Magnetic Stimulation Studies
- Cerebrovascular and Carotid Artery Diseases
- Meningioma and schwannoma management
- Medical Imaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Vestibular and auditory disorders
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Functional Brain Connectivity Studies
- RNA regulation and disease
Ruijin Hospital
2023-2025
Shanghai Jiao Tong University
2023-2025
Background Accurate detection and morphology evaluation of unruptured intracranial aneurysms (UIAs) are essential for patient management. This study aimed to assess the efficacy ultra-high-resolution (UHR) photon-counting detector-CT angiography (PCD-CTA) in detecting UIAs characterizing their morphological features. Methods prospective recruited consecutive participants suspected cerebral vascular diseases who underwent PCD-CTA subsequent digital subtraction (DSA) within 1 month from...
Head and neck CTA requires fine detail evaluation, including characterization of potentially very small vessels intrastent lumens. Blooming artifacts also hinder evaluation.
The central autonomic network (CAN) plays a critical role in the body's sympathetic and parasympathetic control. However, functional connectivity (FC) changes of CAN patients with multiple system atrophy (MSA) remain unknown.To investigate FC alterations MSA patients.Prospective.Eighty-two subjects (47 [44.7% female, 60.5 ± 6.9 years], 35 age- sex-matched healthy controls [HC] [57.1% 62.5 6.6 years]).3-T, resting-state magnetic resonance imaging (rs-fMRI) using gradient echo-planar (EPI),...
Due to a high degree of symptom overlap in the early stages, with movement disorders predominating, Parkinson's disease (PD) and multiple system atrophy (MSA) may exhibit similar decline motor areas, yet they differ their spread throughout brain, ultimately resulting two distinct diseases. Drawing upon neuroimaging analyses altered cortex excitability, potential diffusion mechanisms were delved into, comparisons correlations across groups conducted bid uncover significant pathological...
The magnetic transfer (MT) MRI imaging has long been used for quantifying neuromelanin containing nucleus, but its ability of the magnetization exchange between free water and macromolecules also allowed potential usage in detecting white matter changes. Patients with multiple system atrophy unique pathological changes pontocerebellar regions. In this study, we have not only found significant increase MT contrast MCP regions MSA, proved correlation alteration brainstem or cerebellar atrophy,...
White matter (WM) fiber tracts in the brainstem communicate with various regions cerebrum, cerebellum, and spinal cord. Clinically, small lesions, malformations, or histopathological changes can cause severe neurological disorders. A direct non-invasive assessment approach could bring valuable information about intricate anatomical variations of white nuclei. Although tractography from diffusion tensor imaging has been commonly used to map WM connectivity, it is difficult differentiate...