Gas-phase hydrogen/deuterium exchange reactions have been performed on the 5'- and 3'-nucleotide monophosphates 3',5'-cyclic nucleotides. Following negative mode electrospray ionization transport to a Fourier transform ion cyclotron resonance cell, each nucleotide was reacted with gaseous D2O for up 600 s. Extensive deuterium observed 3'- 5'-nucleotides in mass spectra relative rates of following trend 5'-dCMP > 5'-dAMP 5'-dTMP ≫ 5'-dGMP 3'-dGMP >3'-dAMP ≈ 3'-dCMP 3'-dTMP. At least two...

OBJECTIVES To evaluate the effects of a community pharmacy‐based fall prevention intervention (STEADI‐Rx) on risk falling and use medications associated with an increased falling. DESIGN Randomized controlled trial. SETTING A total 65 pharmacies in North Carolina (NC). PARTICIPANTS Adults (age ≥65 years) using either four or more chronic one (n = 10,565). INTERVENTION Pharmacy staff screened patients for questions from Stopping Elderly Accidents, Deaths, Injuries (STEADI) algorithm. Patients...

For Christian colleges and universities, students’ spiritual formation character development are important outcomes. However, unlike academic outcomes of retention graduation, systematic efforts to measure faith far from ubiquitous. The purpose this article is report the Baylor University address gap between mission measurement. Guided by prevailing theories, an interdisciplinary research team launched Faith Character Study in August 2018. Data collection for broader project involved surveys...

To understand the purpose acquisition of young emerging adults (18-23), scholars claim we need to learn types purposes which they are committing and how conceptualize differently from other related concepts such as future goals good life. address these issues, examined interviews with 229 about their life purpose, goals, conceptions Although interviewees’ fit within shared categories achievement, relationships, religion, moral concerns, important differences also emerged. While one fourth...

The absorption spectrum of benzene vapor in a number gaseous diluents over wide range diluent densities has been obtained. wavelength shifts to the red gases A, H2, N2, CO2, O2, CO, C2H6, and C2H4, blue He Ne. Since light absorber is same each case, relative rates shift with density should be function physical properties diluents. However, no simple correlation found exist between such solvents as polarizability or dielectric constant. Dispersion theory predicts only roughly shifts. No...

This article presents the findings of a 75-participant phenomenological study that examined relationship between students’ expectations their university experience and perception purpose development. A clear dichotomy emerged those who had “holistic” mindset understood as place to develop larger an “instrumental” viewed solely skills enhance future career.

Throughout American history, scholars called Christian higher education by other names. They used terms such as "denominational," "sectarian," "church-related," "church-sponsored," "church-based," and "church-affiliated" to describe education. What these failed include, however, were the increasing number of nondenominational institutions that began emerge in nineteenth century.In The Dying Light, James Burtchaell (1998 Burtchaell, J. T. (1998). dying light: disengagement colleges &...

Paclitaxel has a risk of infusion-related reactions (IRRs) and despite no prospective evidence, is often given with premedication including corticosteroid, H1 antagonist, H2 antagonist (H2RA). Backorders impacted the supply intravenous H2RAs at our center, it was removed as routine premedication. The authors compared incidence IRR in patients treated without H2RA to receiving standard premedication.The reviewed outpatients starting paclitaxel Ottawa Hospital from December 2019 October 2021....

The American Academy of Pediatrics and World Health Organization recommend responsive feeding (RF) to promote healthy eating behaviors in early childhood. This project developed tested a vicarious learning video teach parents RF practices. A was using community-based participatory research methods. Fifty preschoolers were randomly assigned watch Happier Meals or control about education. Knowledge beliefs practices measured 1 week before immediately after intervention. Experimental group...

Abstract Background The Drug Burden Index (DBI) was developed to assess patient exposure medications associated with an increased risk of falling. objective this study examine the association between DBI and medication-related fall risk. Methods used a retrospective cohort design, 1-year observation period. Participants ( n = 1562) were identified from 31 community pharmacies. We examined scores four outcomes. Our primary outcome, which limited participants who received medication review,...

With the advent of combinatorial chemistry and high throughput screening, a major bottleneck in pharmaceutical industry has changed from quickly finding active compounds to limiting them manageable number for proper follow-up. hundreds thousands identified by multitude biological screens, there need be rapid unambiguous methods eliminating false positive, toxic, or otherwise difficult further scrutiny. We have used electrospray ionization mass spectrometry as screening method identify viral...

Community pharmacies are an ideal setting to manage high-risk medications and screen older adults at risk for falls. Appropriate training resources needed successfully implement services in this setting. The purpose of paper is identify the key training, tools, support implementation fall prevention services. service was implemented a network community located North Carolina. Pharmacies were provided with onboard longitudinal project coach. A toolkit contained collect medication information,...

Purpose – The purpose of this paper is to explore the practices used by Australian re-enactors achieve authenticity, a communally agreed measure acceptability in creation an impression, dress, behaviours and accoutrements period, through concepts serious leisure information practices. Design/methodology/approach Re-enactment practical, information-based performative activity. In paper, research styles decision-making processes developed employed its enthusiasts create authentic impressions...

G. R. Newkome, J. M. Robinson and D. Sauer, Chem. Soc., Commun., 1974, 410 DOI: 10.1039/C39740000410

The gas-phase hydrogen-deuterium exchange of phosphorothioate d(GTCAG) and d(TCGAT) has been examined using electrospray Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. monitored for the [M-2H]2−, [M-3H]3−, [M-4H]4− charge states. mole fractions each partially exchanged species have calculated as a function time. rates initial could not be fit to simple exponential functions. results suggest that can adopt more than one conformation, these conformers at different rates....

Courses: This activity can be used in a wide range of classes, including interpersonal communication, introduction to and small group communicationObjectives: After completing this activity, students should able to: (1) define attribution theory, personality attribution, situational bias; (2) provide examples both attributions; (3) recognize why when each type is used. provides an opportunity explore theory bias low-stakes setting, where the ultimate goal deeper understanding itself....

Background: Certain medications place older adults at higher risk for experiencing falls. This is a modifiable factor that may be managed by community pharmacists, but requires prescriber acceptance of recommendations. Previous studies indicate pharmacist recommendations impacted patient-reported concerns. Objective: To examine the relationship between fear falling and Methods: A prospective, observational study design was used. Eligible patients were age 65 received care one 31...

Decades of student persistence and retention literature has brought to light factors social, academic, religious fit that influence a student's decision remain at or depart from an institution. At Christian institutions, increasing pluralism raises the likelihood students will not religiously. This qualitative study 21 first-time, full-time contributes existing by exploring how who already feel they do for reasons work constructing sense research university. Many participants coped with...

A mother of 2 children approaches her community pharmacist.The pharmacist knows that the daughter had been diagnosed with grade I vesicoureteral reflux (VUR) when she was an infant but it has since resolved.The mother's younger son (2 years old) screened and also VUR, although he never a urinary tract infection (UTI).Her took prophylactic antibiotics until VUR resolved, not prescribed antibiotic.The asks pharmacist's opinion about value antibiotic prophylaxis in VUR.