Xiaoqian Sun

ORCID: 0000-0002-1356-3887
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About
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Research Areas
  • Nerve injury and regeneration
  • Medical Research and Treatments
  • Sulfur-Based Synthesis Techniques
  • Metabolomics and Mass Spectrometry Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurological Disease Mechanisms and Treatments
  • Gestational Diabetes Research and Management
  • S100 Proteins and Annexins
  • Drug-Induced Hepatotoxicity and Protection
  • Phytochemicals and Antioxidant Activities
  • Apelin-related biomedical research
  • Fluorine in Organic Chemistry
  • Wnt/β-catenin signaling in development and cancer
  • Paraoxonase enzyme and polymorphisms
  • Electrospun Nanofibers in Biomedical Applications
  • Parkinson's Disease Mechanisms and Treatments
  • Cynara cardunculus studies
  • Synthesis and Catalytic Reactions
  • Connexins and lens biology
  • Genetics and Neurodevelopmental Disorders
  • Seed and Plant Biochemistry
  • Immune cells in cancer

Tianjin University
2024

Tianjin Stomatological Hospital
2024

George Washington University
2024

Clemson University
2022

Liaocheng People's Hospital
2020-2021

Guizhou Normal University
2021

Shandong First Medical University
2021

Taishan Medical University
2020

Affiliated Hospital of North Sichuan Medical College
2018

Shandong University of Traditional Chinese Medicine
2016

Abstract Vascular endothelial growth factor (VEGF) had neuroprotective effects on dopaminergic (DA) neurons. In order to overcome the gastrointestinal digestion and bioaccessibility, VEGF was encapsulated with poly‐lactic‐co‐glycolic acid nanospheres (NS) in prevent degradation until its release. The caudal administration of NS at different doses (1.0, 10.0, 100.0 ng/ml) rats Parkinson's disease lesion evaluated. Intravenous injected dose 1 ng/ml displayed strongest effect than other groups...

10.1111/cbdd.13681 article EN Chemical Biology & Drug Design 2020-03-13

Objective. This study is aimed at exploring the possible neuroprotective mechanism of aspirin and effect bacterial endotoxin lipopolysaccharide (LPS) during cerebral ischaemia-reperfusion (CIRP) injury. Methods. We established three animal models: CIRP, LPS, CIRP+LPS models. Mortality, injured brain area, beam walking test were used to estimate degree injury among rats. Immunohistochemistry immunofluorescence detect activated microglia, matrix metalloproteinase-3 (MMP-3), osteopontin (OPN)....

10.1155/2021/3682034 article EN Disease Markers 2021-11-08

Dental pulp stem cells (DPSCs) have demonstrated significant potential for neuroregeneration. However, a full understanding of the specific mechanism underpinning neural differentiation DPSCs is still required. The Wnt signaling crucial development embryonic system and maintenance adult homeostasis. This study aimed to investigate role Wnt/Ca

10.1016/j.jds.2024.04.011 article EN cc-by-nc-nd Journal of Dental Sciences 2024-04-24

Rett syndrome (RTT), a severe neurodevelopmental disorder caused by mutations in the MeCP2 gene, is characterized cognitive and social deficits. Previous studies have noted hypoactivity medial prefrontal cortex (mPFC) pyramidal neurons of MeCP2-deficient mice (RTT mice) response to both nonsocial stimuli. To further understand neural mechanisms behind deficits RTT mice, we monitored excitatory prelimbic region mPFC during interactions mice. These neurons' activity was closely linked...

10.1523/eneuro.0003-24.2024 article EN cc-by-nc-sa eNeuro 2024-09-12

Abstract The facile protocol allows the synthesis of trifluoroethoxylated 2H‐azirines via cascade reaction enaminones or enamine carboxylic esters with trifluoroethanol.

10.1002/chin.201421111 article EN ChemInform 2014-05-08

This paper aimed to establish animal models which are suitable for the activity found, efficacy evaluation of herbs resistant acute liver injury with syndrome depression and spleen deficiency new drug research development based on corresponding formula syndrome. The symptoms that evaluating rat were extracted according evolution rule etiology pathogenesis in traditional Chinese medicine modern pathological mechanism. Xiaoyao pill silibin meglumine tablets used as counter evidence accordence...

10.4268/cjcmm20162318 article EN China Journal of Chinese Materia Medica 2016-12-01

Background: Optimal gestational weight gain (GWG) is critical for fetal development and maternal health. Few studies have investigated metabolomic markers of GWG. Thus, we performed a metabolome-wide association study with GWG among pregnant women in the US. Methods: This longitudinal included overweight or obese (pre-pregnancy BMI ≥ 25) enrolled Health Pregnancy Postpartum early pregnancy (mean week (GW) at baseline=12). Fasting plasma samples were collected both baseline (N=39) 32 GW...

10.1161/circ.145.suppl_1.p203 article EN Circulation 2022-03-01

To study and analyze the actual clinical effect of nursing intervention in stem cell therapy for stroke patients. A total 9 patients treated with our hospital from September 2018 to 2019 were selected as research analysis objects. All divided into observation group 5 control 4 by random number method. Both groups therapy. Patients conventional methods, methods. The treatment compliance, psychological status, quality life daily living ability before after compared between two groups. There no...

10.18001/trs.7.4.16 article EN Tobacco Regulatory Science 2021-07-31
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