To identify factors associated with opioid use during pregnancy and to compare perinatal morbidity, mortality, healthcare costs between users nonusers.We conducted a cross-sectional analysis of pregnancy-related discharges from 1998 2009 using the largest publicly available all-payer inpatient database in United States. We scanned ICD-9-CM codes for outcomes. Costs care were estimated hospital charges. Survey logistic regression was used assess association maternal each outcome; generalized...

OBJECTIVE: To examine the associations of parity and age at childbirth with maternal cardiovascular disease (CVD). METHODS: The data were from Women's Health Initiative (1993–2022), involving postmenopausal women aged 49–81 years without existing CVD. exposures parity, first childbirth, last all referring to pregnancy lasting least 6 months. outcome was incident CVD events , defined as initial occurrence coronary heart disease, failure, ischemic stroke, or death due these conditions. We...

To investigate the association between gestational age at delivery and perinatal outcomes among gastroschisis-affected pregnancies that result in live birth.We conducted a retrospective cohort study using linked maternal-infant database for more than 2.3 million liveborn neonates Florida from 1998 to 2009. Cases were identified combination of International Classification Diseases, 9th Edition, Clinical Modification, diagnosis procedure codes indicative gastroschisis. We restricted our...

Pre-pregnancy obesity and gestational diabetes mellitus (GDM) are increasingly prevalent independent risk factors for maternal infant morbidities. However, there is a paucity of information on their joint effects health outcomes healthcare costs.A population-based retrospective cohort study was conducted in Florida using validated statewide database covering 1,057,647 infants born between 2004 2009. Using generalized linear modeling, associations levels pre-pregnancy body mass index (BMI)...

Objectives We sought to investigate the feasibility of a behavioral sleep intervention for insomnia, delivered through group prenatal care and relationship this improvements in insomnia symptoms quality.Participants Women receiving reporting pre-pregnancy BMI ≥25 kg/m2 duration <6.5 h per night.Methods Participants were randomized or with intervention, adapted from cognitive therapy (CBT-I) online program Go! Sleep®. In second trimester (T1), late third (T2) 6–8 weeks postpartum (T3) study...

This study sought to examine the differences in pregnancy outcomes with a focus on gestational weight gain for women attending group prenatal care compared standard individual care.A matched case-control was conducted including 65 who chose and 130 care. Women were based prepregnancy body mass index (BMI) category, eligibility midwifery care, age within 5 years.Women choosing had similar gain, birth weight, at birth, mode of birth. did have significantly higher rate exclusive breastfeeding 6...

Cystic fibrosis (CF) is the most common genetic disease in United States (US) and, with development of newer therapeutics, there increased fertility among women CF. We present a series pregnant patients taking novel CF transmembrane conductance regulator (CFTR) modulators and summarize pertinent clinical considerations. All conceived within four months after starting elexacaftor-ivacaftor-tezacaftor. Pulmonary function was stable before during pregnancy. One patient developed transaminitis...

Hypertensive disorders of pregnancy are increasing in prevalence and a leading cause early post-partum readmissions. Stricter blood pressure (BP) target goals for treatment hypertension during have recently been proposed, however, the management less well established. We sought to evaluate clinical factors associated with postpartum readmissions hypertensive disease as thresholds these conducted retrospective cohort study women delivering at tertiary care center between January 2018 May 2022...

Postmortem evaluation following an in utero fetal demise is essential for determining cause of death and counseling regarding future pregnancies. Severe maceration size along with patient desires may limit the physician's ability to perform a complete autopsy. In cases presented, we demonstrate utility postmortem ultrasonography as adjunct traditional autopsy demise.

Abstract Kenny‐Caffey syndrome type 2 (KCS2) and osteocraniostenosis (OCS) are allelic disorders caused by heterozygous pathogenic variants in the FAM111A gene. Both conditions characterized gracile bones, characteristic facial features, hypomineralized skull with delayed closure of fontanelles hypoparathyroidism. OCS KCS2 often referred to as ‐related syndromes a group; although presents more severe, perinatal lethal phenotype. We report novel mutation fetus poorly ossified skull,...

Tuberculosis during pregnancy is associated with increased complications. The wide range of presentations among patients extrapulmonary tuberculosis can make diagnosis and treatment difficult.We present the case a patient Mycobacterium pericarditis presenting in recurrent pericardial effusions. active was made initiated after positive interferon-gamma release assay granulomatous pathology despite negative tuberculin skin testing. Culture tissue obtained by pericardectomy confirmed 1 month...

Pregnancy-associated spontaneous coronary artery dissection (P-SCAD) poses a rare yet critical concern among postpartum individuals, increasingly recognized as significant trigger for acute myocardial infarction. Timely identification, accurate diagnosis, and prompt treatment are paramount clinicians confronted with this condition. Patients P-SCAD commonly manifest signs symptoms akin to syndrome but have different etiology treatment. SCAD is defined non-traumatic, non-iatrogenic separation...

Acute hypertriglyceridemia-induced pancreatitis (HTGP) is an uncommon occurrence during pregnancy. Prompt diagnosis and initiation of treatment are indicated to prevent adverse maternal neonatal outcomes. We present the case a pregnant female who was diagnosed with HTGP at 34 weeks gestation subsequently developed diabetic ketoacidosis (DKA) preeclampsia severe features. describe pathophysiology acute its relation gravid state review available options though data remains limited. Our...

Pregnancies complicated by pulmonary hypertension are associated with a high rate of maternal morbidity and mortality. Pulmonary endarterectomy is curative treatment for in select patients chronic thromboembolic hypertension. Limited data exist regarding the perinatal outcomes following endarterectomy. We present case patient her 20s antiphospholipid antibody syndrome who underwent subsequently carried two pregnancies. Her cardiopulmonary status remained stable throughout both first...

( Am J Obstet Gynecol. 2016;215(4):484.e1–484.e14) Pregnancy-related morbidities, such as preeclampsia and placental infarction abruption, have been linked to the development of future cardiovascular disease (CVD), leading cause death among women in United States. Previous studies mostly focused on these maternal syndromes (PS) long-term risk (up 15 y after giving birth) CVD. This study investigated short-term 5 years first pregnancy) CVD, which would likely occur within mother’s...