A5100781708- Glaucoma and retinal disorders
- Shoulder Injury and Treatment
- Retinal Diseases and Treatments
- Tendon Structure and Treatment
- Biochemical Analysis and Sensing Techniques
- Retinal Imaging and Analysis
- Cell Adhesion Molecules Research
- Immunotherapy and Immune Responses
- Neuroscience of respiration and sleep
- Neuroscience and Neuropharmacology Research
- Trauma Management and Diagnosis
- Immune cells in cancer
- Immune Response and Inflammation
- Inflammation biomarkers and pathways
- Laser Applications in Dentistry and Medicine
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Foot and Ankle Surgery
- Ubiquitin and proteasome pathways
- Flavonoids in Medical Research
Union Hospital
2023
Huazhong University of Science and Technology
2023
Baylor College of Medicine
2022
Weatherford College
2021
Air Force Medical University
2021
Xijing Hospital
2021
Wuhan Union Hospital
2020
Nanjing Medical University
2020
Background: JWA gene is known to down-regulate SP1 and reduces the expression level of Integrin αvβ3. Here, we identified a functional polypeptide (JP1) based on active fragment protein suppress melanoma growth metastasis by inhibiting Methods: We conducted series mouse models evaluate anti-melanoma effect JP1 peptide. 18F-labeled (18F-NFP-JP1) was detected Micro-PET assay demonstrate drug biodistribution. Toxicity test in cynomolgus monkeys pharmacokinetic studies rats were done assess...
Choroidal neovascularization (CNV) is a leading cause of vision loss in the elderly. All approved anti‐angiogenic drug therapies for CNV target vascular endothelial growth factor (VEGF) but confer limited efficacy. Identification other CNV‐related angiogenic factors will facilitate development VEGF‐independent alternative therapies. Here, we applied comparative ligandomics to live mice with or without laser‐induced global mapping CNV‐selective ligands. Secretogranin III (Scg3) previously...
Abstract Calcaneal fractures are rare in pediatric population, with more displaced intra-articular encountered due to the increasing number of high-energy trauma. Operative interventions gaining popularity because unsatisfactory outcomes traditional conservative methods. This study investigated clinical a minimally invasive technique using sinus tarsi approach and external fixator treatment calcaneal patients. Patients who underwent open reduction between January 2010 2018 at our institute...
Abstract BackgroundSepsis is a fatal disease with high rate of morbidity and mortality, during which acute lung injury the earliest most serious complication. Macrophage plays crucial role in initiation progress sepsis. This study meant to explore effect IL-6 knockout CLP induced sepsis.MethodsIn this study, cecal ligation puncture (CLP) was performed on wildtype interleukin 6 (IL-6) C57 mice. General condition death sepsis mice were observed. organ samples (lungs, livers, kidneys hearts)...
Abstract Background: Traditionally, operative treatment for displaced midshaft clavicle fractures in adolescents has been achieved by a plate and screws. However, minimally invasive trend most of the surgeries led pediatric orthopedic surgeons to use elastic stable intramedullary nail (ESIN) fractures. This study aims compare clinical outcomes adolescent patients who were surgically treated with Methods: A total 73 patients, aged between 10 years 14 years, from January 2014 2018. Patients...