E. Kainne Dokubo
A5026076483- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Viral Infections and Outbreaks Research
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Tuberculosis Research and Epidemiology
- COVID-19 epidemiological studies
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Global Maternal and Child Health
- Viral Infections and Vectors
- Disaster Response and Management
- HIV/AIDS Impact and Responses
- Pneumonia and Respiratory Infections
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Bacterial Infections and Vaccines
- HIV-related health complications and treatments
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Global Security and Public Health
- Poverty, Education, and Child Welfare
- Sinusitis and nasal conditions
- Maternal and Neonatal Healthcare
- Blood groups and transfusion
Centers for Disease Control and Prevention
2014-2024
Ministry of Public Health
2023-2024
President's Emergency Plan for AIDS Relief
2022-2024
Cameron University
2023
Global Health Systems Solutions
2021
University of Liberia
2016-2019
Center for Global Health
2016-2018
Nigeria Centre for Disease Control
2017
Ministry of Health and Sanitation
2017
Center for Surveillance, Epidemiology, and Laboratory Services
2015
Events such as the 2014-2015 West Africa epidemic of Ebola virus disease highlight importance capacity to detect and respond public health threats. We describe capacity-building efforts during after in Liberia, Sierra Leone, Guinea progress that was made a result response 4 key areas: emergency response, laboratory capacity, surveillance, workforce development. further ways which those used can be accelerated crisis improve preparedness for future events.
To determine factors associated with HIV status unawareness and assess prevention knowledge condom use among people living HIV/AIDS (PLHIV) in Mozambique.Cross-sectional household-based nationally representative AIDS Indicator Survey.Analyses focused on HIV-infected adults were weighted for the complex sampling design. We identified PLHIV who had never been tested or received their test results prior to this survey. Logistic regression was used unawareness.Of persons positive (N = 1182), 61%...
Equitable access to antiretroviral therapy (ART) for men and women with human immunodeficiency virus (HIV) infection is a principle endorsed by most countries funding bodies, including the U.S. President's Emergency Plan AIDS (acquired syndrome) Relief (PEPFAR) (1). To evaluate gender equity in ART among adults (defined this report as persons aged ≥15 years), 765,087 adult patient medical records from 12 five geographic regions* were analyzed estimate ratio of new enrollees each calendar...
Monitoring prevalence of advanced human immunodeficiency virus (HIV) disease (i.e., CD4+ T-cell count <200 cells/μL) among persons starting antiretroviral therapy (ART) is important to understand ART program outcomes, inform HIV prevention strategy, and forecast need for adjunctive therapies.*,†,§ To assess trends in at initiation 10 high-burden countries during 2004-2015, records 694,138 enrollees aged ≥15 years from 797 facilities were analyzed. Availability national electronic medical...
HIV-1 incidence calculation currently includes recency classification by assay and unsuppressed viral load (VL ≥ 1000 copies/mL) in a recent infection testing algorithm (RITA). However, persons with not virally suppressed taking antiretroviral (ARV) medication may be misclassified.We used data from 13 African household surveys to describe the impact of an ARV-adjusted RITA on estimates.HIV-seropositive samples were tested for using Limiting Antigen (LAg)-Avidity enzyme immunoassay, load,...
Abstract Introduction Achieving optimal HIV outcomes, as measured by global 90‐90‐90 targets, that is awareness of HIV‐positive status, receipt antiretroviral (ARV) therapy among aware and viral load (VL) suppression those on ARVs, respectively, critical. However, few data from sub‐Saharan Africa (SSA) are available older people (50+) living with (OPLWH). We examined progress age, 15–49 (as a comparison) 50+ years, further analyses (55–59, 60–64, 65+ vs. 50–54), in 13 countries (Cameroon,...
Nigeria had the most AIDS-related deaths worldwide in 2014 (170,000), and 46% were associated with tuberculosis (TB). Although treatment of people living HIV (PLHIV) antiretroviral therapy (ART) reduces TB-associated morbidity mortality, incident TB can occur while on ART. We estimated incidence characterized factors after ART initiation Nigeria.We analyzed retrospective cohort data from a nationally representative sample adult patients Data abstracted 3,496 patient records, analyses...
The Eternal Love Winning Africa (ELWA) Clinic was the first clinic to provide free, comprehensive care Ebola virus disease (EVD) survivors in Liberia. objectives of this analysis were describe demographics and symptoms EVD at ELWA from January 2015 through March 2017 identify risk factors for development sequelae.Patients' demographic clinical information collected by chart review June 2016 2017. Associations with sequelae analyzed using chi-square test, t multivariate logistic...
The potential disruption in antiretroviral therapy (ART) services Africa at the start of COVID-19 pandemic raised concern for increased morbidity and mortality among people living with HIV (PLHIV). We describe treatment trends before during interventions implemented to mitigate impact countries supported by US Centers Disease Control Prevention (CDC) through President's Emergency Plan AIDS Relief (PEPFAR).We analysed quantitative qualitative data reported 10,387 PEPFAR-CDC-supported ART...
Background We examined the epidemiology and transmission potential of HIV population viral load (VL) in 12 sub-Saharan African countries. Methods analyzed data from Population-based Impact Assessments (PHIAs), large national household-based surveys conducted between 2015 2019 Cameroon, Cote d’Ivoire, Eswatini, Kenya, Lesotho, Malawi, Namibia, Rwanda, Tanzania, Uganda, Zambia, Zimbabwe. Blood-based biomarkers included serology, recency infection, VL. estimated number people living with...
ABSTRACT Background Cameroon was among the most affected African countries during first wave of COVID‐19 pandemic; however, true prevalence SARS‐CoV‐2 remains unknown. Methods From October to December 2020, we conducted a cross‐sectional, age‐stratified seroepidemiological survey at 30 purposively selected community‐based sites across Cameroon's 10 regional capitals, sampling 10,000 individuals aged 5 years or older. We employed parallel antibody testing algorithm (WANTAI ELISA and Abbott...
KwaZulu-Natal (KZN) Province in South Africa has the highest HIV disease burden country, with an estimated population prevalence of 24.7%. A pilot sentinel surveillance project was undertaken KZN to classify proportion adult patients failing first-line ART and describe patterns drug resistance mutations (DRMs) virological failure (VF).Cross-sectional acquired conducted 15 clinics between August November 2013. Two groups were surveyed: on for 12-15 months (Cohort A) or 24-36 B). Plasma...
Identifying men living with HIV in sub-Saharan Africa (SSA) is critical to end the epidemic. We describe underlying factors of unawareness among aged 15-59 years who ever tested for 13 SSA countries.
Contact tracing is one of the key response activities necessary for halting Ebola Virus Disease (EVD) transmission. Key elements contact include identification persons who have been in with confirmed EVD cases and careful monitoring symptoms, but details implementation likely influence their effectiveness. In November 2015, several months after a major outbreak was controlled Liberia, three members family were positive Duport Road area Monrovia. The cluster provided an opportunity to...
With about 3.4 million HIV-infected persons, Nigeria has the second highest number of people living with HIV (PLHIV) in world. However, antiretroviral treatment (ART) coverage remains low only 748,846 (22%) PLHIV on ART by end 2014. Retention patients pre-ART care is essential to ensure timely initiation. We assessed outcomes enrolled Nigeria's program during 2004-2012.We conducted a nationally representative retrospective cohort study among adults (≥15 years old), enrolling programs...
Background Swaziland has the highest adult HIV prevalence and second rate of TB/HIV coinfection globally. Recently, Ministry Health partners have increased integration co-location services, but timing antiretroviral therapy (ART) relative to TB treatment—a marker program quality predictor outcomes—is unknown. Methods We conducted a retrospective analysis programmatic data from 11 purposefully-sampled facilities evaluate timely ART provision for HIV-positive patients enrolled on treatment...
The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) supports country programs in identifying persons living with HIV infection (PLHIV), providing life-saving treatment, and reducing the spread of countries around world (1,2). CDC used Monitoring, Evaluation, Reporting (MER) data* to assess extent which COVID-19 mitigation strategies affected service delivery across care continuum† globally during first year pandemic. Indicators included number reported HIV-positive test results,...
BackgroundOn May 9, 2015, the World Health Organization (WHO) declared Liberia to be free of known Ebola virus transmission following a 14-month epidemic that resulted in nearly 4,800 deaths within alone [1].Since this declaration, three resurgences have occurred (June November March 2016), and others Sierra Leone (January 2016) Guinea (March 2016).Whereas outbreaks been characterized by Summary Points• Community resistance arising from fear, stigma, lingering trauma devastating outbreak has...