A5025595422- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Catalytic Cross-Coupling Reactions
- Synthesis and biological activity
- Asymmetric Synthesis and Catalysis
- Synthesis and Catalytic Reactions
- Multicomponent Synthesis of Heterocycles
- Fluorine in Organic Chemistry
- Traditional and Medicinal Uses of Annonaceae
- Organoboron and organosilicon chemistry
- Asymmetric Hydrogenation and Catalysis
- Synthetic Organic Chemistry Methods
- Quinazolinone synthesis and applications
- Click Chemistry and Applications
- Fungal Plant Pathogen Control
East China Normal University
2022-2024
Jiangxi Normal University
2019-2020
A dppb and TfOH promoted cascade reaction of o -nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions is developed.
An efficient B(C 6 F 5 ) 3 catalyzed protocol for the synthesis of oxindole fused 1,3-oxazepanes from pyrrolidine substituted aryl alkynones has been developed.
An efficient and convenient procedure for the synthesis of 3-methylthio-1-phenyl-pyrazolo[3,4-d][1,2,4]triazolo[1,5-a]pyrimidin-4-one derivatives (4a–m) via tandem aza-Wittig annulation reactions with iminophosphoranes 1, aryl isocyanate, substituted 2-phenoxyacetohydrazide is described. This protocol provides a simple facile approach to synthesize pyrazolo[3,4-d][1,2,4] triazolo[1,5-a]pyrimidine under mild conditions.
Sixteen novel 3-methylthio-5-substituted benzamido-6-arylamino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4 (5H)-one derivatives (4a–p) were successfully synthesized from iminophosphoranes, aryl isocyanate, and substituted benzoylhydrazine. The structures of the title compounds elucidated by FT-IR, 1H NMR, 13C HRMS. Herbicidal activity 4a–p against Brassica napus (rape), Echinochloa crusgalli (barnyard grass), Cucumis sativus (cucumber), Triticum aestivum (wheat) determined. results showed that...
Base-promoted selective C2–N1 ring-expansion reactions of indolones toward substituted quinolines under mild conditions were developed.
An efficient protocol for the synthesis of [4.6] spirocarbocycles by reacting cyclic β-ketoesters with aryl-fused 1,6-diyn-3-ones has been developed.
A novel and efficient copper-catalyzed transannular ring-closing reaction of eight-membered rings has been developed that provides a straightforward way to synthesize bicyclo[3.3.0]octane derivatives in good yields. Mechanistic studies revealed the pathway might involve chlorination followed by Kornblum reaction. Readily accessible starting materials functional group tolerance make this procedure attractive.
Abstract A novel base‐promoted and highly efficient strategy for preparation of trifluoromethyl‐containing tetrasubstituted olefin derivatives has been developed. The trifluoroacetyl amination alkynes is realized by C−N cleavage trifluoroacetamides without any transition‐metal catalysts. Readily accessible substrates, good functional group tolerance atom economy make this approach attractive the synthesis olefins.