Mansoor Khaledi

ORCID: 0000-0002-1576-5968
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Vibrio bacteria research studies
  • Essential Oils and Antimicrobial Activity
  • Drug-Induced Hepatotoxicity and Protection
  • COVID-19 Clinical Research Studies
  • Gut microbiota and health
  • Helicobacter pylori-related gastroenterology studies
  • MicroRNA in disease regulation
  • Bacteriophages and microbial interactions
  • Ethnobotanical and Medicinal Plants Studies
  • Veterinary medicine and infectious diseases
  • Reproductive tract infections research
  • Galectins and Cancer Biology
  • Streptococcal Infections and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Mesenchymal stem cell research
  • Microbial infections and disease research
  • COVID-19 diagnosis using AI
  • Brucella: diagnosis, epidemiology, treatment
  • Wound Healing and Treatments
  • Antibiotic Use and Resistance
  • Dietary Effects on Health
  • Phytochemistry and biological activity of medicinal plants
  • Tryptophan and brain disorders

Shahrekord University of Medical Sciences
2017-2025

Shahed University
2020-2024

Baqiyatallah University of Medical Sciences
2020-2022

Iran University of Medical Sciences
2020

Shiraz University of Medical Sciences
2020

Abstract Background The gut microbiota plays a crucial role in regulating the host’s immune responses during aging, which was characterized by different abundance of bacteria several age groups. Main body Gut dysbiosis is associated with antibiotic exposure, underlying diseases, infections, hormonal variations, circadian rhythm, and malnutrition, either singularly or combination. appropriate use prebiotics probiotics may be able to prevent reduce this disruption. Conclusion current review...

10.1186/s13213-023-01744-5 article EN cc-by Annals of Microbiology 2024-01-03

Abstract Objective Acinetobacter baumannii ( A. ) has caused many problems in nosocomial infections. Efflux pumps are considered as one of the most important mechanisms resistance this bacterium and have ability to excrete toxic substances such antibiotics out cell. Results In study, 60 isolates were collected from patients several hospitals Tehran, Iran. After diagnosis using standard biochemical methods, pattern antibiotic susceptibility was determined disk diffusion method according CLSI...

10.1186/s13104-020-05387-6 article EN cc-by BMC Research Notes 2020-11-19

This study was conducted to identify patterns of cagA EPIYA motifs in H. pylori strains isolated from patients with gastrointestinal diseases Hospitals Shahrekord, and investigate the association between these biomarkers clinical outcomes due pylori. In this study, 253 were studied within 1395–1396. Histopathological investigations urease test showed that 207 isolates pylori-positive. Then, screening using a molecular technique, PCR, confirmed 159 had cagA. Finally, pattern prevalence...

10.1016/j.heliyon.2020.e04971 article EN cc-by-nc-nd Heliyon 2020-09-01

Diclofenac (DIC) is an NSAID that can cause toxic effects in animals and humans carvacrol (CAR) a monoterpene compound displays effective pharmacological biological actions. The purpose of this work was to assess the influences CAR on DIC-induced liver injury oxidative stress male rats.The Wistar rats were segregated into four groups. Group 1, control group; 2 received DIC-only (10 mg/kg BW, p.o); 3, CAR-only p.o), group 4 DIC plus CAR. serum levels as well activity several liver-associated...

10.4103/ijpvm.ijpvm_178_21 article EN cc-by-nc-sa International Journal of Preventive Medicine 2023-05-01

Abstract The current study was aimed at investigating the prevalence of mutations upstream oprD coding region and its promoters among imipenem-resistant sensitive Pseudomonas aeruginosa isolated from educational hospitals in Yazd City, Iran. All isolates were identified by conventional biochemical tests. Then, antibiotic resistance these determined using disk diffusion method according to CLSI guidelines. Also, E.test performed determine minimum inhibitory concentrations (MIC) imipenem. this...

10.1186/s13568-021-01243-3 article EN cc-by AMB Express 2021-06-05

Background: ABO blood types are not known to cause diseases directly, but they can be vulnerable and surrender health problems. This study aimed evaluate the susceptibility COVID-19 in individuals with different groups at ages. Methods: An electronic record was used this retrospective cohort Shahid Beheshti Hospital. We studied 858 patients who were referred Hospital, we identified 434 of them as using RT-PCR. analysis involved collecting laboratory data demographic information, including...

10.18502/jmb.v12i2.15622 article EN cc-by-nc Journal of Medical Bacteriology 2024-06-02

Abstract The vagina hosts a community of microorganisms known as the vaginal microbiota. This is relatively stable and straightforward, with Lactobacillus species being most dominant members. microbiota has various functions that are essential for maintaining human health balance. For example, it can metabolise dietary nutrients, produce growth factors, communicate other bacteria, modulate immune system, prevent invasion harmful pathogens. When disrupted, lead to diseases infections....

10.1186/s13027-024-00590-7 article EN cc-by Infectious Agents and Cancer 2024-06-14

Diclofenac (DIC) is administrated to treat pain, inflammatory disorders, and dysmenorrhea but kidney problems are the main worries of agent. The literature has revealed that quercetin (QR) anti-inflammatory antioxidant attributes. This study aims highlight possible nephroprotective effects QR on DIC-exposed rats. In this study, animals after exposure DIC (50 mg/kg, i.p) were (100 p.o). Then, levels, as well activity several oxidant anti-oxidant mediators, evaluated. Our results showed...

10.1177/1721727x221086530 article EN cc-by-nc European Journal of Inflammation 2022-04-04

Background: Since drug resistance has become one of the predominant problems health worldwide, it is necessary to use new methods combat drug-resistant bacteria. In this regard, medicinal plants are considered richest sources produce antibiotics. The aim study was investigate antibacterial effects as well total phenolic and flavonoid contents a number collected from Chaharmahal Bakhtiari provinces India, in order their potential for production antibiotics.
 Materials Methods:...

10.15419/bmrat.v5i1.408 article EN Biomedical Research and Therapy 2018-01-23

Acquiring infectious diseases due to resistant agents leads serious problems such as taking higher doses of antibiotics, additional treatments, lengthened hospital stay, and imposing costs. The aim the current study is antibacterial effects hydroalcoholic extracts four Iranian medicinal plants, occurring in Chaharmahal va Bakhtiari, on Staphylococcus aureus Acinetobacter baumanii . In this experimental study, plants were prepared by maceration. To investigate effects, microdilution...

10.24896/eijppr.2017722 article EN International Journal of Pharmaceutical and Phytopharmacological Research 2017-06-27

Background: Hypertension is one of the most common disorders and a major public health problem that causes 20% to 50% world mortality. On other hand, obesity also risk factor for type 2 diabetes, cancer, cardiovascular disease, osteoarthritis has share in costs. Therefore, relationship between body mass index blood pressure been considered. By this study, general, about these indicators age group under 30 years, useful information can be found. Methods: In order collect information,...

10.47552/ijam.v10i1.1225 article EN cc-by International Journal of Ayurvedic Medicine 2019-04-03

Carbapenem-resistant Acinetobacter baumannii are the top urgent antibiotic resistance threat in world. The aims of this study were determination carbapenem-resistant genes and virulence among isolates from hospital environments. In study, A. isolated environments evaluated its resistance, factors, genes. Of 258 samples, 58 showed growth target organism. Antibiotic susceptibility test results considered all to be multidrug-resistant with highest being 36.2% ciprofloxacin; while most effective...

10.52547/jcbior.2.1.14 article EN cc-by-nc Journal of Current Biomedical Reports 2021-01-02
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