A5038357798- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Sperm and Testicular Function
- Toxic Organic Pollutants Impact
- Reproductive Biology and Fertility
- Mercury impact and mitigation studies
- Cystic Fibrosis Research Advances
- Carcinogens and Genotoxicity Assessment
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Analytical chemistry methods development
- Reproductive Health and Technologies
- Urologic and reproductive health conditions
- Per- and polyfluoroalkyl substances research
- Microbial infections and disease research
- Heavy Metal Exposure and Toxicity
- Assisted Reproductive Technology and Twin Pregnancy
- Radio, Podcasts, and Digital Media
- Reproductive tract infections research
Masaryk University
2020-2024
University Hospital Brno
2021-2024
Exposure to bisphenols has been found have adverse effects on male reproductive function in animals. Human exposure is widespread. Bisphenol A (BPA) and its analogues, including bisphenol S (BPS), F (BPF), AF (BPAF) are utilized various consumer products such as food contact materials dental resins. The of these compounds fertility spermatogenesis unclear findings from human studies inconsistent. In this cross-sectional study, we evaluated the influence BPA, BPS, BPF, BPAF (BPs) measured...
Exposure to bisphenols is related negative effects on male reproduction. The exposure associated with several modes of action including impact the blood-testis barrier (BTB) in testes or direct effect spermatozoa. Bisphenols have been detected human seminal plasma, but possible mechanism transfer not clear. Some authors consider through be crucial. Therefore, this work, we compared normozoospermic men and after vasectomy who interrupted vas deferens their ejaculate does contain testicular...
Microfluidic sperm selection systems (MFSS) are increasingly being used and appear to be a promising adjunct in assisted reproductive treatment (ART). They practical, easy use, often presented as highly effective. In this study, we assessed the effectiveness of Ca0 microfluidic chip compared swim-up (SU) technique with respect oxygen radicals spermiogram parameters. Sample from each patients was separated by both methods after that evaluated for concentration, motility, morphology, DNA...
Abstract Sperm separation for ICSI is an essential step in realization of the IVF procedures. The method microfluidic sperm cells using chips has been applied more and frequently recent years. This often presented as extremely gentle to spermatozoa decreasing significantly concentration with fragmented DNA when compared conventional methods. aim our study was verify a chip system from perspective its potential select non-fragmented DNA. We tested efficiency this against swim-up method. In we...
Abstract Study question Can we quantitatively determine concentrations of endocrine disruptors namely bisphenol A and S in seminal fluid? Summary answer We developed selective analytical method to simultaneously screen for the presence (BPA) (BPS). What is known already The male reproductive system involves processes, which may be influenced by disruption chemicals called (EDs). There a growing evidence that EDs such as responsible decline health. To date, claimed adverse effects on...
Abstract The endocrine disruptors are chemicals with the capacity to influence physiological processes in organism, most often through hormonal control. They present environment and products of daily use. found food, released from plastic bottles for water, cosmetics or fertilizers. Latest research suggests that they can be plastics used IVF laboratories even manipulation cultivation media isolation fertilization gametes subsequent embryos. Permanent long-term utilization these substances...
Abstract Study question Is there a relationship between concentration of Bisphenol A (BPA), Zn contents and Zn/Cu ratio in seminal fluid spermiogram parameters men with varicocele? Summary answer Our results document correlations BPA, sperm motility. We found that the negative effect BPA can be attenuated by higher levels. What is known already range environmental factors including organic endocrine disruptors affects spermatogenesis. Bisphenols are often used production plastics. an...
Abstract Study question Can we quantitatively, accurately, and simultaneously determine concentrations of essential toxic elements in seminal fluid? Summary answer We developed validated a multi-element panel to quantify plasma one single assay. What is known already It well that certain are involved normal spermatogenesis, sperm function male fertility. Elements, such as zinc, copper, calcium, important for the maintenance maturation etc. On other hand, even low-level exposure elements,...
Abstract Study question Is there a relationship between concentration of bisphenol S in seminal fluid and spermiogram parameters? Summary answer Bisphenol was detected 81% plasma samples. Negative correlation found BPS total sperm count normozoospermic men. What is known already Human spermatogenesis can be influenced by range chemicals present our environment. (BPS) very frequent compound commonly used as softener production plastics, where it has replaced A. It an endocrine disruptor...