The activated partial thromboplastin time (aPTT) and anti-Xa activity are used for monitoring unfractionated heparin (UFH) therapy in children may not be optimal.Determine correlations of aPTT, UFH dose children. Single centre prospective cohort study receiving UFH. aPTT results from routine coagulation were collected. Thirty-nine (median age 18 days) enrolled. There was no relationship between (r2=0.12) or (r2=0.03) (r2=0.22). do accurately monitor

Unfractionated heparin (UFH) is frequently prescribed for children the prevention and treatment of thrombosis; however, its safety efficacy have not been assessed. The aim this single center, prospective cohort study was to determine incidence major bleeding recurrent thrombosis in receiving UFH. Major defined a priori as: central nervous system or retroperitoneal bleeding, resulting UFH being stopped overt causing drop hemoglobin >20 g/dL less than 24 h. events occurred 9/38 (24%, 95% CI...

To establish the incidence and factors associated with hospital-acquired hyponatremia in pediatric surgical patients who received hypotonic saline (sodium 40 mmol/L plus potassium 20 mmol/L) at rate suggested by Holliday Segar's formula for calculations of maintenance fluids.Prospective, observational, cohort study.Pediatric intensive care unit.: Eighty-one postoperative patients.None.Incidence < or = 135 mmol/L). Univariate analysis was conducted post surgery 12 hrs 24 hrs. Mean values were...

Alveolar capillary dysplasia is a fatal disorder of the lung that requires biopsy for diagnosis. We reviewed course patients with alveolar following implementation an early strategy between 1997–2002. performed immunohisto-chemical studies on all tissue specimens. diagnosed 7 cases dysplasia. 6/7 pre-mortem by biopsy. Median time admission and was 6.5 days. All survived but died withdrawal active therapy after confirmation In 1 patient we demonstrated histological findings congenital acinar...

Objective: Pediatric Index of Mortality 2 (PIM2) is an up-to-date mortality prediction model in the public domain that has not yet been widely validated. We aimed to evaluate this score population patients admitted our pediatric intensive care unit. Design: Prospective cohort study. Setting: Multidisciplinary unit a general university hospital Buenos Aires, Argentina. Patients: All consecutive between January 1, 2004, and December 31, 2005. Interventions: None. Measurements Main Results:...

Ventilator-associated pneumonia is considered the second most frequent infection in pediatric intensive care, and there agreement on its association with higher morbidity increased healthcare costs. The goal of this study was to apply a bundle for ventilator-associated prevention as process quality improvement PICU Hospital Italiano de Buenos Aires, Argentina, aiming decrease baseline rate by 25% every 6 months over period 2 years.Quasi-experimental uninterrupted time series.PICU...

To determine the agreement between venous oxygen saturation in right atrium (Srao2) and pulmonary artery (Svo2) critically ill pediatric patients.Retrospective, observational study.Multidisciplinary intensive care unit from a general university hospital.Thirty children whom catheter (PAC) was inserted for catecholamine refractory shock (septic cardiogenic, n = 18) postoperative management (liver cardiac transplant, 12).Ninety measurements of Srao2 Svo2 were obtained after placement PAC every...

Associations between cumulative fluid balance and a prolonged duration of assisted mechanical ventilation have been described in adults. The aim this study was to evaluate whether the first 48 hours initiation associated with process among children Pediatric Intensive Care Unit (PICU).Retrospective cohort patients PICU o, Hospital Italiano de Buenos Aires, 1/1/2010 6/30/2012. Balance calculated percentage body weight; defined as >7 days, confounders were registered. Univariate multivariate...

Objective: We describe an infrequent but potentially lethal complication: iatrogenic injury of the internal mammary artery after central venous catheterization. Design: Report cases. Setting: Pediatric intensive care unit. Patients: The first patient we report on is a 3-yr-old girl who was severely neurologically damaged and admitted to pediatric unit for aspiration pneumonia septic shock. Immediately vein cannulation left jugular vein, suffered hypotension cardiac arrest, secondary...

RESUMENIntroducción.El objetivo fue validar y aplicar un instrumento para medir satisfacción de padres pacientes internados en

Introduction.The use of checklists to increase adherence evidence-based practices is not yet widespread in pediatric intensive care units.The objective this study was achieve 90% compliance with studied using an ad hoc checklist.Population and methods.Time series quasiexperimental conducted ventilated children hospitalized the unit.Studied included sedation breaks, plateau pressure ≤ 30 cm H 2 O, fraction inspired oxygen 60%, maintenance headboard at > 30°, chlorhexidine mouthwash, weekly...

The Functional Status Scale (FSS) was developed to measure acquired morbidity in pediatric patients.To estimate the incidence of intensive care unit (PICU) and presence associated factors, describe functional status after hospital discharge.Prospective cohort. All PICU admissions between August 2016 July 2017. FSS used during hospitalization up 1 year discharge. A univariate analysis performed investigate morbidity-associated factors.A total 842 patients were included. at 3.56 % (30/842)...

The author replies: First, we appreciate the interest in our article shown by Dr. Hasan and also opportunity given to answer his concerns. points out two main issues. he states that there is discordance between definition of hyponatremia introduction (<130 mmol/L) used as primary end point (<136 mmol/L): no such because sentence “acute severe hyponatremia, defined a reduction plasma sodium (PNa) <130 mmol/L, increasingly recognized cause morbidity mortality hospitalized patients” (1) fact...

The aim of the study was to evaluate success rate transpyloric tube (TPT) placement using air gastric insufflation technique in patients hospitalized Pediatric Intensive Care Unit. POPULATION, MATERIALS AND METHODS: data were collected retrospectively from a prospective filled database. TPT positioning defined as successful by evaluation its distal end abdominal X-ray. Demographic information, rate, duration procedure registered. Descriptive statistics used analyze data.There 37 procedures...

RESUMENIntroducción.Se han descrito asociaciones entre balance de fluido acumulado y mayor estadía en asistencia respiratoria mecánica adultos.El objetivo fue evaluar si el las primeras 48 horas iniciada la se asociaba a su prolongación niños internados Terapia Intensiva Pediátrica (UCIP).Métodos.Cohorte retrospectiva pacientes