A5080462099- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Biosensing Techniques and Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Terahertz technology and applications
- Semiconductor Lasers and Optical Devices
- Lipid Membrane Structure and Behavior
- Electrochemical sensors and biosensors
- Spectroscopy and Quantum Chemical Studies
- Epigenetics and DNA Methylation
- Acoustic Wave Resonator Technologies
- 3D Printing in Biomedical Research
- Polymer Surface Interaction Studies
- Analytical Chemistry and Sensors
- Protein Structure and Dynamics
- Advanced Electron Microscopy Techniques and Applications
- Nanomaterials and Printing Technologies
- Force Microscopy Techniques and Applications
- Nanofabrication and Lithography Techniques
- Intravenous Infusion Technology and Safety
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Chemical Sensor Technologies
- Single-cell and spatial transcriptomics
- Molecular Junctions and Nanostructures
- Superconducting and THz Device Technology
- Microfluidic and Bio-sensing Technologies
Bar-Ilan University
2012-2020
Alzheimer's Association of Israel
2018
Institute of Nanotechnology
2014-2018
Hebrew University of Jerusalem
1983
The low-frequency vibrational (LFV) modes of biomolecules reflect specific intramolecular and intermolecular thermally induced fluctuations that are driven by external perturbations, such as ligand binding, protein interaction, electron transfer, enzymatic activity. Large efforts have been invested over the years to develop methods access LFV due their importance in studies mechanisms biological functions biomolecules. Here, we present a method measure based on Raman spectroscopy combines...
A microfluidic-based fluorometric methylation assay for functional regulation of methyltransferase activity compatible with high-throughput screening chemical and biological libraries.
The work reported herein describes the controlled creation of uniform thiol-functionalized siloxane-anchored self-assembled monolayers (SAMs) and their selective transformation into intramonolayer (bridging) disulfides. These disulfides provide for efficient immobilization (bio)molecules bearing pendant thiols or disulfides, with no need added oxidant. unambiguous development this surface chemistry required analytical methods that distinguish thiol disulfide moieties on a surface. Physical...
Microfluidic chips provide a powerful platform for high-throughput screening of diverse biophysical systems. The most prevalent detection methods are fluorescence based. Developing new readout techniques microfluidics focusing on quantitative information in the low signal regime is desirable. In this work, we combine well-established immunoassay approach, with magnetic nanoparticles, highly sensitive imaging technique. We offer to integrate microfluidic array into scanning superconducting...
Low Frequency Vibrational (LFV) modes of peptides and proteins are attributed to the lattice vibrations dependent on their structural organization self-assembly. Studies taken in order assign specific absorption bands low frequency range self-assembly behavior have been challenging. Here we used a single stage Raman (LF-Raman) spectrometer study series diastereomeric analogue investigate effect LF-Raman modes. The variation analogues resulted distinct groups, as confirmed by transmission...
The evaporation dynamics of subnanoliter chained droplets from the cleaved facet a standard fiber are monitored by reflectivity measurements incident light. rate doubly distilled water is calibrated as function temperature and relative humidity (RH). experimental uncertainty in corresponds to measurement errors ±0.5 °C or ±1.5% RH. analysis distinguishes between binary mixtures gasoline methanol, used alternative fuel blends, with mixing ratios that differ 5%. Finally, properly estimates...
Abstract Cancer is the second leading cause of death globally. Matching proper treatment and dosage crucial for a positive outcome. Any given drug may affect patients with similar tumors differently. Personalized medicine aims to address this issue. Unfortunately, most cancer samples cannot be expanded in culture, limiting conventional cell‐based testing. Herein, presented microfluidic device that combines microarray cell microscopy. The can perform 512 experiments test chemosensitivity...
Microfluidic-based protein arrays are promising tools for life sciences, with increased sensitivity and specificity. One of the drawbacks this technology is need to create fresh surface chemistry immobilization at beginning each experiment. In work, we attempted include process functionalization as part fabrication device, which would substitute time consuming step array To end, employed a novel modification using self-assembled monolayers (SAMs) immobilize biomolecules within channels...
The evaporation rate of water droplets is evaluated as a function temperature and relative humidity using fiber-optic sensor. Either parameter may be monitored when the other known, with uncertainties 0.5 deg. C or 1.5% humidity. Further, sensor used in analysis negative control synthetic solutions, made to mimic human urine. Samples binary mixtures solution at different volume ratios are categorized correlation recorded dynamics, 87% success. results represent an important first step...
Summary Many electronic devices containing quartz crystals operate in an environment exposed to radiation, and it is important therefore investigate the effects of radiation on crystals. In present work we show that technique thermoluminesce nce TL can serve as a good tool for such investigation. We report measured temperature range 15 300 K. The measurements have been carried out separately various growth sectors (namely +X, -X, +Z, -Z) Y plates cut from grown bar unswept Electronic Grade...