A5006796997- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Heart Rate Variability and Autonomic Control
- Obstructive Sleep Apnea Research
- Pediatric Pain Management Techniques
- Hemodynamic Monitoring and Therapy
- Cardiovascular Syncope and Autonomic Disorders
- Nausea and vomiting management
- Respiratory Support and Mechanisms
- Genetic and phenotypic traits in livestock
- Tracheal and airway disorders
- Non-Invasive Vital Sign Monitoring
- Cardiac Arrest and Resuscitation
- Burn Injury Management and Outcomes
- Meat and Animal Product Quality
- EEG and Brain-Computer Interfaces
- Neonatal Respiratory Health Research
- Ruminant Nutrition and Digestive Physiology
- Injury Epidemiology and Prevention
- Spectroscopy and Chemometric Analyses
- Enhanced Recovery After Surgery
Sorbonne Université
2016-2025
Assistance Publique – Hôpitaux de Paris
2012-2025
Université Paris Cité
2013-2025
Groupe de recherche clinique en anesthésie réanimation médecine périopératoire
2020-2025
Hôpital Armand-Trousseau
2015-2024
Unité Mixte de Recherche sur les Herbivores
2010-2022
Laboratoire de Psychologie du Développement et de L’Education de l’enfant
2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2022
Hypertension pulmonaire : physiopathologie et innovation thérapeutique
2022
Université Paris 1 Panthéon-Sorbonne
2020
This study reports the practices and morbidity of 24,165 anaesthetics performed over a 30-month period in paediatric teaching hospital.Data describing adverse events during anaesthesia postanaesthesia care unit (PACU) were collected prospectively from 1 January 2000 to 30 June 2002 on an audit form as part Quality Assurance Program. All surgical specialties are covered except for open heart surgery neurosurgery.A total 724 reported 1105 PACU. Respiratory represented 53% all intraoperative...
BackgroundNeonates and infants requiring anaesthesia are at risk of physiological instability complications, but triggers for peri-anaesthetic interventions associations with subsequent outcome unknown.MethodsThis prospective, observational study recruited patients up to 60 weeks' postmenstrual age undergoing surgical or diagnostic procedures from 165 centres in 31 European countries between March 2016 January 2017. The primary aim was identify thresholds pre-determined variables that...
Analgesia and nociception can not be specifically monitored during general anesthesia. Movement of the patient or hemodynamic variations are usually considered as symptoms insufficient analgesia. The measure skin conductance (SC) allows an assessment peripheral sympathetic activity. analgesia-nociception index (ANI) provides evaluation parasympathetic activity based on heart rate variability. These two non-invasive monitors might allow a better perioperative nociception.Describe profiles SC...
Abstract Background Pupillometry has shown promising results for assessing nociception in anesthetized patients. However, its benefits clinical practice are not demonstrated. The aim of this prospective randomized study was to evaluate the impact intraoperative pupillometry monitoring on perioperative opioid consumption major gynecologic surgery. Methods After receiving ethics committee approval and written consent patients, American Society Anesthesiologists status I II women undergoing...
Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was analyse interventions related anaesthesia tracheal intubations European cohort identify their clinical consequences.We performed a secondary analysis multicentre observational trial (NEonate Children audiT Anaesthesia pRactice IN Europe [NECTARINE]) neonates small with difficult intubation. primary endpoint incidence intubation complications. endpoints were risk factors for severe...
The world is currently facing an unprecedented healthcare crisis caused by the COVID-19 pandemic. objective of these guidelines to produce a framework facilitate partial and gradual resumption intervention activity in context group has endeavoured minimum number recommendations highlight strengths be retained 7 predefined areas: (1) protection staff patients; (2) benefit/risk patient information; (3) preoperative assessment decision on intervention; (4) modalities preanaesthesia...
Background This study was design to assess clinical agitation, electroencephalogram (EEG) and autonomic cardiovascular activity changes in children during induction of anesthesia with sevoflurane compared halothane using noninvasive recording EEG, heart rate, finger blood pressure. Methods Children aged 2-12 yr premedicated midazolam were randomly assigned one three techniques: 7% 100% O2 (group SevoRAPID); 2%, 4%, 6%, SevoINCR); or 1%, 3%, 3.5% 50% N2O-50% HaloN2O). An additional group who...
To investigate the differences between heart rate (HR) variability and pulse (PR) variability, short-term of finger wave ECG signals were studied in 10 children with a fixed ventricular pacemaker rhythm (80 beats/min). Ten healthy sinus served as reference population. Distal PR HR measured continuously using Finapres device an respectively. Power spectra for calculated both supine orthostatic positions. In paced subjects, exhibited characteristic respiratory peak, although flat. Similarly,...
In Brief BACKGROUND: this prospective study, we compared the relationship between propofol concentrations and bispectral index (BIS) in children versus young adults anesthetized with target-controlled infusion (TCI) of propofol. METHODS: Forty-five prepubertal subjects (children) 45 postpubertal (adults) were studied. All patients TCI propofol, based on Kataria et al.'s model for Schnider adults. data from BIS system continuously recorded using Rugloop software. Remifentanil was administered...
The aim of this study was to identify the best model describe pharmacokinetics and pharmacodynamics in prepubertal children therefore calculate corresponding pharmacodynamic parameters. In addition, confirm our method, a group postpubertal subjects also studied.Sixteen (9.5 yr, range 6-12) 13 adults (22 13-35) were included. Induction performed by plasma target-controlled infusion propofol (6 microg/ml) based on Kataria Schnider adults. relationship bispectral index predicted concentrations...
Background Sevoflurane has become the gold standard for inhalation induction in children. However children as adults, epileptiform electroencephalographic signs have been described under high concentrations of sevoflurane. The aim this study was to determine minimal alveolar concentration (MAC) sevoflurane associated with occurrence major (MES) 50% steady-state conditions. MAC MES (MAC MES) determined 100% oxygen and addition nitrous oxide or after injection alfentanil (ALFENTA). Methods...
In European countries, silage-free feeding is an ancient tradition and has a particularly positive reputation among consumers. the present study, we compared grass-based forages from same plot conserved as hay or silage fed fresh either on pasture indoors, evaluated differences in sensory properties of milk uncooked pressed cheese. All herbage first cut grassland dominated by perennial ryegrass was harvested day preserved silage. The regrowth used for strip grazing green indoors. Balanced...
The clinical benefits to be expected from intraoperative nociception monitors are currently under investigation. Among these devices, the Analgesia Nociception-Index (ANI) has shown promising results sevoflurane anesthesia. Our study investigated ANI-guided remifentanil administration propofol We hypothesized that ANI guidance would result in reduced consumption compared with standard management. This prospective, randomized, controlled, single-blinded, bi-centric included women undergoing...
Rapid assessment of hemostasis during postpartum hemorrhage (PPH) is essential to allow characterization coagulopathy, estimate bleeding severity, and improve outcome. Point care (POC) coagulation monitors could be great interest for early diagnosis treatment disorders in PPH.Women with ongoing PPH >500 mL who clinically required an thromboelastography (TEG) were included. The primary aim this retrospective observational cohort study was assess the predictive accuracy TEG parameters...