A5021208741- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Spine and Intervertebral Disc Pathology
- Airway Management and Intubation Techniques
- Plant-Microbe Interactions and Immunity
- Anesthesia and Neurotoxicity Research
- Fungal and yeast genetics research
- Nausea and vomiting management
- Fungal Biology and Applications
- Pregnancy-related medical research
- Neurosurgical Procedures and Complications
- Cardiovascular Syncope and Autonomic Disorders
- Mycorrhizal Fungi and Plant Interactions
- Nosocomial Infections in ICU
- Spinal Hematomas and Complications
- Hernia repair and management
- Plant Pathogens and Fungal Diseases
- Metabolism and Genetic Disorders
- Hemodynamic Monitoring and Therapy
- Plant Pathogenic Bacteria Studies
- Cerebrovascular and Carotid Artery Diseases
- Image Retrieval and Classification Techniques
- Pelvic and Acetabular Injuries
- Epilepsy research and treatment
Health Sciences University of Hokkaido
2024
Tokyo University of Agriculture and Technology
2003-2017
Institute of Agrobiological Sciences
2008
Saitama University
2005-2006
Tama University
2005
Jichi Medical University
1993-2004
RIKEN
1990-2002
Sapporo Medical University
1996
Jichi Medical University Hospital
1992
Meikai University
1990
The biological role of a secretory catalase the rice blast fungus Magnaporthe oryzae was studied. internal amino acid sequences partially purified in culture filtrate enabled us to identify its encoding gene as catalase-peroxidase gene, CPXB, among four putative genes for or M. oryzae. Knockout drastically reduced level activity and supernatant conidial suspension (SCS), increased sensitivity exogenously added H₂O₂ compared with control strains, suggesting that CPXB is major confers...
The conidial germ tube of the rice blast fungus, Magnaporthe grisea, differentiates a specialized cell, an appressorium, required for penetration into host plant. Formation appressorium is also observed on artificial solid substrata such as polycarbonate. A novel emerging tube-specific gene, CBP1 (chitin-binding protein), was found in cDNA subtractive differential library. coded putative extracellular protein (signal peptide) with two similar chitin-binding domains at both ends central...
The rice blast fungus Magnaporthe oryzae differentiates a specialized infection structure called an appressorium to invade cells. In this report, we show that CBP1, which encodes chitin-deacetylase, is involved in the induction phase of differentiation. We demonstrate enzymatic activity Cbp1 critical for formation. M. has six CDA homologues addition Cbp1, but none these are indispensable observed chitosan localization at fungal cell wall using OGA488. This observation suggests Cbp1-catalysed...
We examined the localization of probe-accessible chitin in Magnaporthe oryzae, which causes rice blast disease, during early infection process and functions two genes encoding a chitin-binding domain (ChBD). Invasive hyphae first-invaded cell showed little staining with fluorescently labeled wheat germ agglutinin, probe to detect chitin. However, second-invaded cell, strong fluorescence, treatment chitinase diminished signal. Fourteen ChBD family 18 carbohydrate-binding module (CBM18) were...
Background: Increasing evidence indicates that amrinone, a phosphodiesterase fraction III (PDE‐III) inhibitor, has relative efficacy as an initial treatment for cardiovascular depression after bupivacaine in experimental setting. This study was performed to compare the effects of other new PDE‐III inhibitors, milrinone and olprinone, with those amrinone reversing bupivacaine‐induced depression. Methods: In sevoflurane‐anaesthetized dogs, infused intravenously at 1 mg · kg −1 min until mean...
We report a 51-year-old woman with alopecia caused by sarcoidosis. The lesion enlarged within 4 years and only repeated biopsies enabled the diagnosis. medical work-up revealed that patient had asymptomatic pulmonary involvement. Scarring is rare complication of sarcoidosis biopsy from active margin may lead to
We developed an efficient method to analyze gene function and expression of the rice blast fungus. constructed a GATEWAY binary vector, which generates gene-targeted disruptant carrying green fluorescent protein under native promoter target gene. Using this method, knockout efficiency patterns two hypothetical genes were determined.
Hypomelanosis of Ito (HI), a neurocutaneous syndrome, is characterized by skin depigmentation and skeletal, muscular, central nervous system, cardiac, renal manifestations. A wide variety cutaneous manifestations besides have been reported. Herein we describe 23-year-old woman with HI whose extracutaneous symptoms included severe mental motor impairment, convulsions, deformity the orofacial region. She also had obesity, asthma, multiple allergies, hypersensitivity. Although no were...