- SARS-CoV-2 and COVID-19 Research
- Bacillus and Francisella bacterial research
- Viral Infections and Outbreaks Research
- COVID-19 Clinical Research Studies
- Drug-Induced Hepatotoxicity and Protection
Central University of Rajasthan
2020-2021
One major obstacle in designing a successful therapeutic regimen to combat COVID-19 pandemic is the frequent occurrence of mutations SARS-CoV-2 resulting patient variations. Out four structural proteins namely, spike, envelope, nucleocapsid and membrane, envelope protein governs virus pathogenicity induction acute-respiratory-distress-syndrome which cause death patients. These effects are facilitated by viroporin (ion-channel) like activities protein. Our current work reports metagenomic...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain that has not been ever found in humans before December 2019. Both the disease 2019 (COVID-19) case fatality rate and deaths per million population top 10 affected countries are increasing lot due to ever-increasing number of cases among facilitated by increased affinity SARS-CoV-2 bind human angiotensin-converting enzyme (ACE2) receptors. While human-to-human transmission happens through close contact with...