A5087486860- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Inflammasome and immune disorders
- Extracellular vesicles in disease
- Blood Coagulation and Thrombosis Mechanisms
- Venous Thromboembolism Diagnosis and Management
- RNA Interference and Gene Delivery
- Systemic Lupus Erythematosus Research
- Advanced biosensing and bioanalysis techniques
- Renal Diseases and Glomerulopathies
- Dermatological and COVID-19 studies
Universidade de São Paulo
2024-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2022-2024
Hospital Universitário da Universidade de São Paulo
2024
Background Antiphospholipid syndrome (APS) is characterized by thrombosis or pregnancy complications associated with the presence of antiphospholipid antibodies (aPLs). Although exact mechanisms are unclear, aPLs can increase expression tissue factor on platelets, leukocytes, and endothelial cells, leading to hypercoagulability. Extracellular vesicles (EVs) also be released during this process play a key role in immune regulation related APS. Aims To evaluate association between circulating...
Exacerbated inflammation and coagulation are a hallmark of COVID-19 severity. Extracellular vesicles (EVs) intercellular transmitters involved in inflammatory conditions, which capable triggering prothrombotic mechanisms. Since the release EVs is potentially associated with COVID-19-induced coagulopathy, aim this study was to evaluate changes inflammation- hypercoagulability-related during first month after symptom onset determine whether they disease Blood samples patients mild or severe...