A5026209560- Intracerebral and Subarachnoid Hemorrhage Research
- Nerve injury and regeneration
- Parkinson's Disease Mechanisms and Treatments
- Transcranial Magnetic Stimulation Studies
- Spinal Hematomas and Complications
- Stroke Rehabilitation and Recovery
- Histone Deacetylase Inhibitors Research
- Cerebral Palsy and Movement Disorders
- Neuroscience and Neural Engineering
- Botulinum Toxin and Related Neurological Disorders
- Cancer-related gene regulation
- Neurosurgical Procedures and Complications
- Vestibular and auditory disorders
- Neurogenesis and neuroplasticity mechanisms
- Balance, Gait, and Falls Prevention
- Motor Control and Adaptation
- Neurological disorders and treatments
- Muscle activation and electromyography studies
- Adipose Tissue and Metabolism
- Neurological Disorders and Treatments
- Nutrition and Health in Aging
- Neurological and metabolic disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced Neuroimaging Techniques and Applications
- Nuclear Receptors and Signaling
Hokkaido University
2019-2025
Chubu University
2024-2025
Health Sciences University of Hokkaido
2021
Ritsumeikan University
2017-2021
Higashi Nagoya National Hospital
2010-2019
Nagoya University
2008-2017
Magnetic fields are being used for detailed anatomical and functional examination of the human brain. In addition, evidences their efficacy in treatment brain dysfunctions is accumulating. Transcranial static magnetic field stimulation (tSMS) a recently developed technique non-invasively modifying functions. tSMS, strong small magnet when placed over skull can temporarily suppress Its modulatory effects persist beyond time stimulation. However, neurophysiological mechanisms underlying...
Background: Progressive supranuclear palsy (PSP) is characterized by early postural instability and gait dysfunction, with frequent falls. Rehabilitation an important therapeutic approach for motor dysfunction in patients PSP. However, no conclusions have yet been drawn regarding the beneficial effects of rehabilitation PSP, including optimal duration differences treatment among PSP subtypes. Herein, we investigated short-term separately analyzed on PSP-Richardson’s syndrome (RS)...
Abstract Transcranial static magnetic stimulation (tSMS) has been focused as a new non-invasive brain stimulation, which can suppress the human cortical excitability just below magnet. However, non-regional effects of tSMS via network have rarely studied so far. We investigated whether over left primary motor cortex (M1) facilitate right M1 in healthy subjects, based on hypothesis that functional suppression cause paradoxical facilitation contralateral reduction interhemispheric inhibition...
Integration of visual, vestibular, and proprioceptive sensations contributes to postural control. People with peripheral visual field loss have serious instability. However, the directional specificity stability sensory reweighting caused by gradual remain unclear. What are effects on static control? Fifteen healthy young adults participated in this study. The participants were asked stand quietly a foam surface. Three conditions virtual (90°, 45°, 15°) provided head-mounted display, ground...
Due to the lack of effective therapies, stem cell transplantation is an anticipated treatment for chronic intracerebral hemorrhage (ICH), and higher survival engraftment are considered be key recovery. Mesenchymal stromal cells (MSCs) compounded with recombinant human collagen type I scaffolds (CellSaics) have a potential compared solo-MSCs, we investigated validity CellSaic in ICH model. Rat CellSaics (rCellSaics) were produced by rat bone marrow-derived MSC (rBMSCs). The secretion...
Background Progressive supranuclear palsy (PSP) is a parkinsonian-like progressive neurodegenerative syndrome. Key clinical features include ocular motor dysfunction, postural instability, and cognitive dysfunction. Maintaining improving balance function gait are very important for patients with PSP severe dysfunction repeated falls. In addition, have poor response to pharmacological treatment; hence, rehabilitation key approach in dealing this However, no conclusion on the beneficial...
Introduction Skeletal muscle mass loss has been associated with decreased physical performance; however, the body composition characteristics in progressive supranuclear palsy (PSP) are not well understood. We investigated parameters, focusing on skeletal mass, patients PSP and compared them those of healthy older adults. Methods This retrospective cross-sectional study included 39 30 adults (control group). Using a multi-frequency bioelectrical impedance analysis, we measured index (SMI),...
Epigenetic regulation is involved in post-stroke neuroplasticity. We investigated the effects of intracerebral hemorrhage (ICH) on histone acetylation and gene expression related to neuronal plasticity bilateral sensorimotor cortices, which may affect function. Wistar rats were randomly divided into SHAM ICH groups. performed surgery stereotaxically based microinjection a collagenase solution group. Foot fault cylinder tests evaluate motor functions at 4-time points, including pre-ICH...