Chen Cao

ORCID: 0000-0002-1704-3459
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Brain Tumor Detection and Classification
  • Advanced MRI Techniques and Applications
  • Advanced Surface Polishing Techniques
  • Advanced Neuroimaging Techniques and Applications
  • Cardiovascular Health and Disease Prevention
  • Radiomics and Machine Learning in Medical Imaging
  • Intracranial Aneurysms: Treatment and Complications
  • Advanced Neural Network Applications
  • Medical Imaging and Analysis
  • Advanced Machining and Optimization Techniques
  • Medical Image Segmentation Techniques
  • Advanced materials and composites
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Advanced machining processes and optimization
  • Stock Market Forecasting Methods
  • Medical Imaging Techniques and Applications
  • Advanced X-ray and CT Imaging
  • Functional Brain Connectivity Studies
  • Peripheral Neuropathies and Disorders
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Aluminum Alloys Composites Properties
  • Autoimmune Neurological Disorders and Treatments
  • Digital Imaging for Blood Diseases

Tianjin Huanhu Hospital
2017-2025

Tianjin University
2022-2024

Tianjin Medical University
2021-2024

Capital University
2024

Capital Medical University
2024

Jilin University of Finance and Economics
2024

Shandong University of Technology
2022-2023

Tianjin First Center Hospital
2023

Nankai University
2023

Second Hospital of Tianjin Medical University
2023

The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While a quantitative evaluation of lesions on magnetic resonance images (MRIs) is effective in clinical diagnosis, manually segmenting commonly used, which is, however, tedious and time-consuming task. Therefore, how to segment fully automated manner has recently extracted extensive attentions. Considering that clinically acquired MRIs usually have thick slices, we propose 2D-slice-based...

10.1109/access.2018.2872939 article EN cc-by-nc-nd IEEE Access 2018-01-01

Purpose To investigate whether patients with capsular stroke (CS) and pontine (PS) involving the motor pathway have different types of structural damage reorganization. Materials Methods With institutional review board approval after obtaining written informed consent, magnetic resonance imaging data were prospectively acquired in 115 CS, 47 PS, 116 control subjects by using four imagers from three hospitals. Patients lesions left right hemispheres analyzed (timing follow-up imaging: mean,...

10.1148/radiol.2017161055 article EN Radiology 2017-08-04

This study aimed to investigate the effects of lesion side and degree motor recovery on gray matter volume (GMV) difference relative healthy controls in right-handed subcortical stroke. Structural MRI data were collected 97 patients with chronic ischemic stroke 79 controls. Voxel-wise GMV analysis was used patients. Compared controls, right-lesion demonstrated increase (P < 0.05, voxel-wise false discovery rate correction) bilateral paracentral lobule (PCL) supplementary area (SMA) right...

10.1016/j.nicl.2017.01.031 article EN cc-by-nc-nd NeuroImage Clinical 2017-01-01

<h3>BACKGROUND AND PURPOSE:</h3> Intracranial atherosclerotic plaque features are potential factors associated with recurrent stroke, but previous studies only focused on a single lesion, and few investigated them perfusion impairment. This study aimed to investigate the association among whole-brain features, deficit, stroke recurrence. <h3>MATERIALS METHODS:</h3> Patients ischemic due intracranial atherosclerosis were retrospectively collected categorized into first-time recurrent-stroke...

10.3174/ajnr.a7402 article EN cc-by American Journal of Neuroradiology 2022-01-20

Acute ischemic stroke (AIS) has been a common threat to human health and may lead severe outcomes without proper prompt treatment. To precisely diagnose AIS, it is of paramount importance quantitatively evaluate the AIS lesions. By adopting convolutional neural network (CNN), many automatic methods for lesion segmentation on magnetic resonance imaging (MRI) have proposed. However, most CNN-based should be trained large amount fully labeled subjects, label annotation labor-intensive...

10.1155/2021/3628179 article EN cc-by Computational and Mathematical Methods in Medicine 2021-01-29

Background Dual-energy CT (DECT) provides several novel methods to assess thrombus perviousness. We aimed evaluate whether the perviousness measured with DECT is associated improved recanalisation and better functional outcomes in acute ischaemic stroke (AIS) patients endovascular thrombectomy (EVT). Methods 108 AIS middle cerebral artery occlusion who underwent angiography on admission received EVT treatment between April 2020 September 2023 were retrospectively analysed. Thrombus...

10.1136/svn-2024-003661 article EN cc-by-nc-nd Stroke and Vascular Neurology 2025-02-24

Currently, the selection of patients with acute anterior large vessel occlusions (LVOs) for endovascular thrombectomy (EVT) is primarily based on dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) or computed tomography (CT) perfusion imaging. This study investigated consistency between hypoperfused tissue (HPT) (time to maximum >6 s, Tmax s) volumes estimated by corrected and uncorrected multidelay pseudo-continuous arterial spin labeling (pCASL) DSC-PWI in LVOs also...

10.21037/qims-24-1560 article EN Quantitative Imaging in Medicine and Surgery 2025-03-01

A comprehensive assessment of collateral status can yield profound insights into the ischemic mechanism in patients experiencing acute stroke. This study aims to investigate whether time-variant and tissue-level characteristics may serve as predictors for functional outcomes undergoing endovascular thrombectomy (EVT) through application machine learning (ML) algorithms, stratify postoperative neurological recovery these patients. In this retrospective study, 128 stroke characterized by...

10.21037/qims-24-1073 article EN Quantitative Imaging in Medicine and Surgery 2025-04-30

Abstract This study combined the Latent Dirichlet Allocation topic model to explore potential topics of new energy vehicle (NEV) policies and their impacts on corporate social responsibility (CSR) enterprises. The results reveal that financial subsidies, infrastructure development, environmental protection are most popular topics. And these three have significant positive CSR enterprises, with construction having impact. Additionally, intensity impact large‐scale enterprises is more compared...

10.1002/csr.2867 article EN Corporate Social Responsibility and Environmental Management 2024-05-30

In this study, we aimed to investigate the classification of symptomatic plaques by evaluating models generated via two different approaches, a radiomics-based machine learning (ML) approach, and an end-to-end approach which utilized deep (DL) techniques with several representative model frameworks. We collected high-resolution magnetic resonance imaging (HRMRI) data from 104 patients carotid artery stenosis, who were diagnosed either (SPs) or asymptomatic (ASPs), in medical centers. 74 SPs...

10.3389/fcvm.2023.1173769 article EN cc-by Frontiers in Cardiovascular Medicine 2023-07-06

Background: Atherosclerotic plaque locations in the carotid bulb increasingly have been found to be associated with patterns of ischemic lesions and progression. However, occurrence is a complex process. We aimed investigate characteristics geometric hemodynamic parameters among patients body apical plaques identify mechanism formation location. Methods: Consecutive single stenosis (50–99%) were enrolled retrospectively. Patients divided into groups based on Plaque location identified...

10.1159/000531584 article EN Journal of Vascular Research 2023-01-01

Early studies have indicated that the cortico-rubro-spinal tracts play important roles in motor dysfunction after stroke. However, differential involvement of rubral branches capsular and pontine stroke, their associations with impairment are still unknown. The present study recruited 144 chronic stroke patients 91 normal controls (NC) from three hospitals, including 102 cases (CS) 42 (PS). branches, bilateral corticorubral (CRT), dentatorubral (DRT), rubrospinal (RST), cortico-spinal tract...

10.1016/j.nicl.2019.102090 article EN cc-by-nc-nd NeuroImage Clinical 2019-01-01

High-performance iron-based Al2O3 magnetic abrasive powder (MAP) prepared by combining plasma molten metal with sprayed is used for finishing (MAF) of AZ31B magnesium alloy to remove surface defects such as creases, cracks, scratches, and pits generated during the manufacturing process workpiece, reduce roughness improve its wear corrosion resistance. In order solve problem splash in MAF process, force analysis MAP processing area conducted, a composite pole device was designed simulated...

10.3390/mi13091369 article EN cc-by Micromachines 2022-08-23

10.1016/j.ijporl.2018.12.022 article EN International Journal of Pediatric Otorhinolaryngology 2018-12-19

<h3>BACKGROUND AND PURPOSE:</h3> Not all tandem occlusions diagnosed on traditional vascular imaging modalities, such as MRA, represent actual complete ICA occlusion. This study aimed to explore the utility of high-resolution vessel wall in identifying true and screening patients for their suitability endovascular recanalization. <h3>MATERIALS METHODS:</h3> Patients with no signal MRA were retrospectively reviewed. Two neuroradiologists independently reviewed images assess whether there...

10.3174/ajnr.a6452 article EN cc-by American Journal of Neuroradiology 2020-02-27

Background: Myelin oligodendrocyte glycoprotein (MOG) antibody–associated encephalitis is a new clinical phenotype of inflammatory demyelinating diseases. Some MOG antibody–positive patients with central nervous system events present isolated seizures. However, there are gaps in the epidemiological knowledge regarding seizures adults. This study characterized features and treatment Methods: We reviewed all admitted to Tianjin Huanhu Hospital between Jan. 1st 2017 2022, screen seizures,...

10.2147/ndt.s444853 article EN cc-by-nc Neuropsychiatric Disease and Treatment 2024-01-01

Background Acute ischemic stroke (AIS) is an acute brain injury caused by sudden occlusion of a blood vessel. Endovascular therapy the most effective way to restore flow. However, despite restoration flow in some patients, their clinical prognosis often remains unsatisfactory. Albumin has shown neuroprotective effects animal models AIS. Therefore, this study aims evaluate safety, feasibility, and efficacy local arterial infusions 20% human serum albumin solution as adjuvant after...

10.3389/fneur.2024.1455388 article EN cc-by Frontiers in Neurology 2024-09-30
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