A5074899417- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Dementia and Cognitive Impairment Research
- Neurological Disease Mechanisms and Treatments
- Blood Pressure and Hypertension Studies
- Air Quality and Health Impacts
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health, Environment, Cognitive Aging
- Health disparities and outcomes
- Lipoproteins and Cardiovascular Health
- Nutrition, Genetics, and Disease
- Aging, Elder Care, and Social Issues
- Cardiovascular Health and Disease Prevention
- Moyamoya disease diagnosis and treatment
- Neurological Complications and Syndromes
- Syphilis Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Genetic diversity and population structure
- Cardiovascular Disease and Adiposity
- Folate and B Vitamins Research
- Intensive Care Unit Cognitive Disorders
- Cancer-related molecular mechanisms research
- Vestibular and auditory disorders
- Gestational Diabetes Research and Management
Tianjin Huanhu Hospital
2016-2025
Peking University
2004-2025
Foshan Maternity and Child Health Care Hospital
2020-2025
Guangdong Medical College
2018-2025
Tianjin Medical University
2015-2025
Inner Mongolia Agricultural University
2024
Nankai University
2024
Jiangxi Academy of Agricultural Sciences
2024
Animal Science Research Institute
2024
Ministry of Agriculture and Rural Affairs
2024
Dyslipidemia is a modifiable risk factor for cardiovascular disease (CVD). We investigated the prevalence and associated factors of dyslipidemia- raised total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-C), low high-density (HDL-C), non-high-density (non-HDL-C) in rural urban China.We analyzed data from 136,945 participants aged 40-100 years CNSSPP project 2014. was defined by NCEP-ATP III 2016 Chinese guidelines management dyslipidemia adults. Complete on demographic,...
In China, stroke is a major cause of mortality, and long-term physical cognitive impairment. To meet this challenge, the Ministry Health China Stroke Prevention Project Committee (CSPPC) was established in April 2011. This committee actively promotes prevention control China. With government financial support 838.4 million CNY, 8.352 people from 536 screening points 31 provinces have received follow-up over last seven years (2012–2018). 2016, CSPPC issued plan to establish centers. shorten...
Background: High doses of estrogen can promote tumor regression in postmenopausal women with hormone-dependent breast cancer, but the mechanism is unknown. We investigated molecular basis this process by using LTED cells, which were derived growing MCF-7 cancer cells under long-term (6–24 months) estrogen-deprived conditions. Methods: treated and various concentrations 17β-estradiol (estradiol) assayed their growth counting measured apoptosis annexin V staining DNA fragmentation. Using...
Total homocysteine (tHcy) levels are associated with secondary vascular events and mortality after stroke. The aim of this study was to investigate whether tHcy in the acute phase a stroke contribute recurrence cerebro-cardiovascular mortality.A total 3799 patients were recruited hospital admission for ischemic Levels measured within 24 hours primary admission. Patients followed median 48 months.During follow-up period, 233 (6.1%) died. After adjustment age, smoking status, diabetes...
The overall global burden of stroke is considerable and increasing. In China, the leading cause death disability. For this study, we used data from National Stroke Screening Survey in 2012 2010 Chinese population sixth Census Populations to calculate a standardized (by age, gender, education) prevalence. Prevalence, risk factors, management were compared by site. prevalence rate survival patients study aged 60 older was 4.94% total. Hypertension most prevalent factor for stroke. Compared...
Background Carotid atherosclerosis ( CA ) is a reflector of generalized that associated with systemic vascular disease. Data are limited on the epidemiology carotid lesions in large, nationally representative population sample. We aimed to evaluate prevalence detected by ultrasonography and related risk factors based national survey China. Methods Results A total 107 095 residents aged ≥40 years from China National Stroke Prevention Project underwent ultrasound examination. Participants...
Women with breast cancer who have responded to initial hormonal therapy frequently experience additional remissions upon further endocrine manipulation. We postulate that hypersensitivity estradiol (E2) may serve as a mechanistic explanation for these secondary responses. previously provided evidence of using an in vitro model system and demonstrated the role mitogen-activated protein kinase (MAP kinase) process adaptation long-term deprivation. In present study, we wished demonstrate E2...
The association between oxidized low-density lipoprotein (oxLDL) and the long-term prognosis of stroke is unclear. aim this study to investigate whether oxLDL levels contribute subtypes.All patients with ischemic were recruited from SOS-Stroke (Study Oxidative Stress in Patients With Acute Ischemic Stroke) classified into 5 different subtypes, according TOAST criteria (Trial Org 10172 Stroke Treatment). We measured followed up at 1 year after onset. analyzed clinical outcomes death poor...
Background: Metabolic syndrome (MetS) is a cluster of major risk factors for cardiovascular diseases. We aimed to estimate prevalence and distribution MetS among middle-aged elderly adults in China.Methods: The present analysis used data from national study 2014–2015. defined by different definitions, compared results the previous nationally representative studies illustrate possible temporal changes prevalence.Results: estimated was 18.4% ATP III criteria, 34.0% revised 26.9% IDF criteria....
Abstract Effective management of dyslipidemia is important. This study aimed to determine the awareness, treatment, control, and determinants in middle-aged older Chinese adults China. Using data from 2015 China National Stroke Screening Prevention Project (CNSSPP), a nationally representative sample 135,403 aged 40 years or more were included this analysis. Dyslipidemia was defined by Third Report Cholesterol Education Program Expert Panel on Detection, Evaluation, Treatment High Blood...
We aimed to investigate the prevalence of stroke and related vascular risk factors in adult population aged 40 years older China. conducted a prospective cross-sectional survey nationally representative sample 207323 individuals from all 31 Chinese provinces 2013. Data were used analyze by age, sex, geographical regions educational level. The age-standardized was significantly higher men than women age groups (P < 0.001). rural urban residents among both inversely associated with There...
Dipteronia (order Sapindales) is an endangered genus endemic to China and has two living species, D.sinensis D. dyeriana. The plants are closely related the Acer, which also classified in order Sapindales. Evolutionary studies on have been hindered by paucity of information their genomes plastids. Here, we used next generation sequencing characterize transcriptomes complete chloroplast both species. A comparison species identified a total 7814 orthologs. Estimation selection pressures using...
Ischemic stroke (IS) is a serious central nervous system disease. Post-IS complications, such as post-stroke cognitive impairment (PSCI), depression (PSD), hemorrhagic transformation (HT), gastrointestinal dysfunction, cardiovascular events, and infection (PSI), result in neurological deficits. The microbiota-gut-brain axis (MGBA) facilitates bidirectional signal transduction communication between the intestines brain. Recent studies have reported alterations gut microbiota diversity...
<b><i>Background/Aims:</i></b> The aim of this article was to estimate the prevalence and determine sociodemographic risk factors for dementia, Alzheimer's disease (AD) vascular dementia (VaD) among individuals residing in rural northern China. <b><i>Methods:</i></b> Between 2011 2012, residents aged ≥60 years areas China were clinically assessed symptoms AD VaD. Diagnoses made using established criteria standard procedures....
It is not known how total homocysteine (tHcy) levels change during the transition from acute stroke to post-stroke convalescence or whether tHcy changes occurring after period are associated with recurrence of cerebro-cardiovascular events. Levels were measured ischemia and again three months. Patients followed for a median 18 (range: 12-36) A 2800 patients who had at least two measurements enrolled between February 2012 June 2014; 2587 presented ischemic 213 cerebral hemorrhage. During...
Avian leukosis virus subgroup K (ALV-K) is a new of avian (ALV) that was first identified in Chinese native chickens recent years. To further understand the molecular epidemiology and evolutionary diversity ALV-K, this study investigated 73,664 chicken plasma samples collected from Jiangxi flocks. The results showed ALV-J most predominant ALV subtype chickens, with high positivity rate 4.34%. From 2021 to 2023, there gradual upward trend proportion positive numbers ALV-K among ALV-positive...
The association between cardiac dysfunction and functional outcome in acute ischemic stroke (AIS) is not clear. We aimed to investigate the relationship routinely assessed left ventricular ejection fraction (LVEF) outcomes patients with AIS.
Reversible cerebral vasoconstriction syndrome (RCVS) is an infrequent disease characterized by severe headaches with or without focal neurological deficits seizures and a reversible of arteries. The Orpha number for RCVS ORPHA284388. However, triggered blood transfusion rare. Here we provided the clinical, neuroimaging outcome data patients diagnosed resulting from red cells transfusion.We retrospectively identified 7 presenting after January 2010 to May 2014. information on clinical...
microRNAs are regulatory molecules regarded as important in the pathogenesis of different types tumors. microRNA-216a (miR-216a-5p) has been identified a tumor suppressor multiple malignancies. However, role miR-216a-5p small cell lung cancer (SCLC) remains obscure. The objective this study was to investigate miR-216a-5p/Bcl-2 axis SCLC pathogenesis.All experimental methods used were follows: microarray analysis, culture, transient, and stable gene transfection; real-time fluorescence PCR;...