- Nutrition and Health in Aging
- Diet and metabolism studies
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Oral microbiology and periodontitis research
- Advanced Combustion Engine Technologies
- Nutritional Studies and Diet
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Urinary Bladder and Prostate Research
- Blood Pressure and Hypertension Studies
- Engineering Applied Research
- Hormonal and reproductive studies
- Biopolymer Synthesis and Applications
- Cardiovascular Health and Disease Prevention
- Vehicle emissions and performance
- Diabetes Management and Education
- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
- Oral Health Pathology and Treatment
- Pancreatic function and diabetes
- Maritime Transport Emissions and Efficiency
- Heart Rate Variability and Autonomic Control
- Oxidative Organic Chemistry Reactions
- Pediatric Urology and Nephrology Studies
Matsushita Memorial Hospital
2010-2025
Kyoto Prefectural University of Medicine
2015-2025
Yokohama Rosai Hospital
2014-2025
Wakayama Medical University
2024
Nara Medical University
1992-2024
Panasonic (China)
2018-2024
Pan American Health Organization (Cuba)
2024
Panasonic (Poland)
2024
Takeda (Japan)
2008-2024
Novo Nordisk (Italy)
2024
Metabolically healthy obesity (MHO) is a unique phenotype that apparently protects people from the metabolic complications of obesity. The association between MHO and incident CKD unclear. Thus, this study investigated CKD.A total 3136 Japanese participants were enrolled in an 8-year follow-up cohort 2001. status was assessed by common clinical markers: BP, triglycerides, HDL cholesterol, fasting plasma glucose concentrations. Body mass index ≥25.0 kg/m(2) defined as proteinuria or eGFR <60...
To investigate the acute effects of coronavirus disease 2019 (COVID-19) on lifestyle and metabolic parameters in patients with type 2 diabetes mellites. This cross-sectional retrospective cohort study induced 203 who completed a questionnaire regarding stress levels lifestyles. Data levels, sleep time, exercise, total diet, snack, prepared food intake were obtained from questionnaires. The changes body weight or HbA1c determined by comparing values at time was administered to those noted 3...
Abstract Background Previous studies have investigated the association between ratio of triglycerides (TG) to high-density lipoprotein cholesterol (HDL-C) and incidence diabetes in adults discovered that a high TG/HDL-C was linked an elevated risk new-onset diabetes. However, comparison predicting development among lipid profiles including ratio, cut-off value has received limited attention. We examined relationship onset addition applicable for onset. Methods This study included 120,613...
ABSTRACT Aims In Japan, several prediction models and scoring systems for type 2 diabetes have been reported; however, none high utility. We developed a new clinical model the onset of diabetes. Materials Methods The development dataset was obtained from 72,124 Japanese employees who participated in health check‐up programme conducted by Panasonic Corporation (Osaka, Japan), were aged 40 years or older, diabetes‐free at baseline, followed‐up up to 10 years. external validation 12,885...
We examined whether the serum matrix metalloproteinase-2 (MMP-2) level and MMP-2 density could be predictors of development extension prostate cancer. Serum samples were collected before any clinical treatment from 98 patients with cancer 76 benign prostatic hyperplasia (BPH). Control sera obtained 70 healthy men. The was determined by 1-step enzyme immunoassay. A newly defined parameter dividing volume, which measured ultrasonography. mean in significantly higher than control BPH groups....
Sarcopenia has reportedly been associated with increased risk of mortality in general populations. However, few studies have investigated the association between sarcopenia and older people type 2 diabetes mellitus (T2D). This study aimed to investigate effect on incident all-cause T2D.Low muscle strength were set at handgrip <28 kg for men <18 women, low skeletal mass index (SMI), evaluated using impedance body composition analyzer, SMI <7.0 kg/m2 <5.7 women. People who had both diagnosed...
In recent years, sarcopenic obesity has been considered central pathological factors in diabetes. This study aimed to compare the effect of luseogliflozin, a sodium-glucose co-transporter-2 inhibitor (SGLT2i), on comparison that low-carbohydrate diet (LCD). Twenty-week-old male db/db mice were fed normal (Ctrl), LCD, and with 0.01% w/w luseogliflozin (SGLT2i) for eight weeks. Skeletal muscle mass grip strength decreased LCD group compared those control group, while they increased SGLT2i...
To investigate the antibacterial activity of mucosal Th1 and Th2 immune responses induced nasally orally, mice were immunized with vaccine containing fimbrial protein Porphyromonas gingivalis, a causative agent for destructive chronic inflammation in periodontium, cholera toxin (CT) as adjuvant. Nasal low doses fimbriae (10 micrograms) CT (1 microgram) Ag-specific Th1/Th2-type response CD4+ T cells effector tissues, including nasal passage submandibular glands, which accounted generation...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation M. Nishiuchi, I. Daito, Ikegami, H. Daido, Mori, S. Orimo, K. Ogura, A. Sagisaka, Yogo, Pirozhkov, Sugiyama, Kiriyama, Okada, Kanazawa, Kondo, T. Shimomura, Tanoue, Y. Nakai, Sasao, D. Wakai, Sakaki, P. Bolton, W. Choi, J. Sung, Lee, Oishi, Fujii, Nemoto, Souda, Noda, Iseki, Yoshiyuki; Focusing spectral...
OBJECTIVE Recent study has suggested that not only the presence of hypertension but also variability in systolic blood pressure (SBP) are risk factors for vascular disease and organ damage. The aim this was to investigate relationship between visit-to-visit SBP change urinary albumin excretion (UAE) or development albuminuria patients with type 2 diabetes. RESEARCH DESIGN AND METHODS We measured 354 consecutive at every visit during 1 year calculated coefficient variation (CV) SBP. performed...
Genetic control of alpha-amylase (alpha-1,4-glucan glucanohydrolase, EC 3.2.1.1.) production by Bacillus subtilis 168 was studied from the standpoint that bacteria is dependent on a long-lived messenger ribonucleic acid and obeys following equation: E = kappa integral X-DT where x cell mass at time t, alpha amylase produced, t culture time, productivity constant. So constand (kappa) obtained slope straight line plot formed versus total cells accumulated over during process. The results were...
Tween 60 (polyoxyethylene sorbitan monostearate) has been found to be the most effective derivative of fatty acid in accumulating l-glutamic biotin-sufficient medium. The effect was exceedingly subject influence addition time ester, and this observed also on growth curve Brev. lactofermentum. Changes caused by varied ester corresponded those concentration biotin medium that did not contain 60. patterns fermentation course two corresponding conditions, such as 3 μg/l 20 μg/l-Tween mg/ml,...
Suzuki, K., Okada, H., Yamauchi, M., Oka, Y., Kodama, S. and Watanabe, M. Qualitative Quantitative Analysis of Phosphorylated ATM Foci Induced by Low-Dose Ionizing Radiation. Radiat. Res. 165, 499–504 (2006).We examined the formation phosphorylated ataxia telangiectasia mutated (ATM) foci in exponentially growing normal human diploid cells exposed to low doses X rays. were detected immediately after irradiation, number decreased as time irradiation increased. The kinetics was comparable that...
Higher proportions of hemorrhagic stroke and lacunar infarction were reported in rural Japan compared with those Western countries. We examined the relative subtypes an urban Japanese city where westernized lifestyles are more common than areas.Stroke registration was performed 1992, 1997, 2002 for residents > or =40 years age who admitted acute strokes to all 10 hospitals =90 beds Yao City, Osaka, Japan. Strokes classified as intraparenchymal hemorrhage, subarachnoid ischemic (embolic...
Aim To investigate the association between sarcopenia and blood pressure parameters in older patients with type 2 diabetes. Methods This was a cross‐sectional study of 146 Body composition evaluated by bioimpedance analysis. The skeletal muscle mass index (kg/m ) defined as appendicular / square height. Patients both handgrip strength <26 kg for men <18 women, <7.0 kg/m <5.7 women were diagnosed sarcopenia. We measured systolic (SBP) at every visit 1 year calculated coefficient...