- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Radiation Detection and Scintillator Technologies
- thermodynamics and calorimetric analyses
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Air Quality Monitoring and Forecasting
- Advances in Oncology and Radiotherapy
- Calibration and Measurement Techniques
- Breast Cancer Treatment Studies
- Meningioma and schwannoma management
- Photoacoustic and Ultrasonic Imaging
- Trigeminal Neuralgia and Treatments
- Glioma Diagnosis and Treatment
- Advanced Sensor Technologies Research
- Scientific Measurement and Uncertainty Evaluation
- Atomic and Subatomic Physics Research
- Laser Design and Applications
- Head and Neck Surgical Oncology
- Analytical Chemistry and Sensors
- bioluminescence and chemiluminescence research
University of Chicago
2020-2022
University of California, San Diego
2018-2019
University of Wisconsin–Madison
2013-2016
Madison Group (United States)
2013-2014
To characterize the stacked and staggered dual-layer multileaf collimator (MLC) on HalcyonTM system.The novel MLC assembly was reviewed compared to widely used MillenniumTM 120-leaf system. We investigated positioning stability over 70 days using Machine Performance Check (MPC) data. evaluated leaf transmission, penumbra, end effect, edge effect. Leaf transmission through distal, proximal, both layers measured with a Farmer chamber, by comparing an open closed field. penumbra film for three...
Abstract Halcyon™ is a single‐energy (6 MV ‐ FFF ), bore‐enclosed linear accelerator. Patient setup performed by first aligning to external lasers mounted the front of bore, and then loading isocenter through pre‐defined couch shifts. There no light field, optical distance indicator or pointer mechanism, so positioning verified imaging with kV scheduled become available in future. TG ‐51 reference dosimetry was successfully for this imaging‐based paradigm. The beam quality conversion factor,...
To investigate the plan quality and doses to heart, contralateral breast (CB), ipsilateral lung (IL), (CL) in tangential treatments using Halcyon linac with megavoltage setup fields.Radiotherapy treatment plans beams from 25 cancer patients previously treated on a C-arm were replanned for Halcyon. Thirteen corresponded right-sided breasts 12 left-sided breasts, all dose prescription of 50 Gy fractions. Plans created following imaging techniques: low-dose (LD) MVCBCT, high-quality (HQ) LD-MV...
In this work, we investigated the effect on workflow and setup accuracy of using surface guided radiation therapy (SGRT) for patient setup, megavoltage cone beam CT (MVCBCT) or kilovoltage (kVCBCT) imaging fixed IMRT volumetric-modulated arc (VMAT) treatment delivery with Halcyon linac.We performed a retrospective investigation 272 fractions, three different workflows. The first second workflows used MVCBCT delivery, one also SGRT setup. third kVCBCT VMAT delivery. Workflows were evaluated...
The quantity of relevance for external beam radiotherapy is absorbed dose to water (ADW). An interferometer was built, characterized, and tested measure ADW within the range interest using temperature dependence refractive index water. used radiation-induced phase shifts a laser passing through (10 × 10 10) cm3 water-filled glass phantom, irradiated with 6 MV photon from medical linear accelerator. field size (7 7) cm2 measured at depth 5 cm in phantom. intensity interference pattern...
Purpose MRI is the gold‐standard imaging modality for brain tumor diagnosis and delineation. The purpose of this work was to investigate feasibility performing stereotactic radiosurgery (SRS) with a 0.35 T MRI‐guided linear accelerator (MRL) equipped double‐focused multileaf collimator (MLC). Dosimetric comparisons were made vs conventional C‐arm‐mounted linac high‐definition MLC. Methods quality MRL single‐isocenter SRS treatment plans evaluated as function target size series spherical...
Primary Standard Dosimetry Laboratories establish the standards of absorbed dose to water (ADW) using calorimetry. This is because calorimetry most direct method account for energy imparted matter by radiation. The traditional framework based on use thermistors measure temperature changes. There are some drawbacks in radiation and different approaches measurement under investigation. One these techniques uses dependence refractive index with an interferometer radiation-induced work presents...
Purpose: Interferometry‐based calorimetry is a novel technique to measure radiation‐induced temperature changes allowing the measurement of absorbed dose water (ADW). There are no mechanical components in field. This also has possibility obtaining 2D distributions. The goal this investigation calorimetrically‐measure doses between 2.5 and 5 Gy over single projection photon beam using interferometry compare results with calculated TG‐51 linac calibration. Methods: ADW was determined by...
Purpose: To identify the variables limiting resolution of a Michelson interferometer used to measure phase shifts (PS) in water as part radiometric calorimeter. Methods: We investigated output stability He-Ne laser and diode. The short long term fringe pattern was tested with different types lasers, thermal insulation arrangements, damping systems optical mounts optimize system performance. PS were induced by electrically heating 1 cm quartz cuvette located one arms. calculated from...
Purpose: To develop and implement a high spatial resolution calorimeter methodology to measure absorbed dose water (ADW) using phase shifts (PSs) of light passing through phantom compare measurements with theoretical calculations. Methods: Radiation-induced temperature changes were measured the PSs He-Ne laser beam (10×10×10) cm3 phantom. Michelson interferometer recording time-dependent fringe patterns on CCD camera. The was positioned at center radiation field. A Varian 21EX used deliver...
Purpose: To investigate the feasibility of using phase shift measurements visible light to determine absorbed dose water. minimum resolution optical system a Michelson interferometer for measuring radiation induced changes in temperature water and quantify additional heating produced by light. Methods: A was modeled with water‐filled cell one its arms. The anticipated change calculated 2 Gy irradiation. observed intensity incident on detector different volumes doses. caused laser also...