A5052506563- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- Erythropoietin and Anemia Treatment
- Vascular Tumors and Angiosarcomas
- Cancer Immunotherapy and Biomarkers
- MRI in cancer diagnosis
- Effects of Radiation Exposure
- Pharmacological Effects and Toxicity Studies
- Lung Cancer Diagnosis and Treatment
- Cardiac tumors and thrombi
- Lymphoma Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Glioma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
Peter MacCallum Cancer Centre
2016-2025
The University of Melbourne
2011-2025
Health Affairs
2021
European Organisation for Research and Treatment of Cancer
2021
All India Institute of Medical Sciences
1990-2020
Chaudhary Charan Singh Haryana Agricultural University
2018
St Vincent's Hospital
2016
University of Tübingen
2016
Radiation Oncology Associates
2013
Pain and Rehabilitation Medicine
2011
Objective To assess the feasibility and safety of stereotactic ablative body radiotherapy ( SABR ) for renal cell carcinoma RCC in patients unsuitable surgery. Secondary objectives were to oncological functional outcomes. Materials Methods This was a prospective interventional clinical trial with institutional ethics board approval. Inoperable enrolled, after multidisciplinary consensus, intervention informed consent. Tumour response defined using Response Evaluation Criteria In Solid Tumors...
Image-guided radiotherapy (IGRT) increases the accuracy of treatment delivery through daily target localisation. We report on toxicity symptoms experienced during treatment, with and without IGRT in prostate cancer patients treated radically. Between 2006 2009, acute data for ten were collected prospectively onto standardized assessment forms. Toxicity was scored radiotherapy, according to Common Terminology Criteria Adverse Events V3.0, 275 before after implementation a fiducial marker...
Abstract This study aimed to compare the oncological results between unplanned excision (UE) and planned (PE) of malignant soft tissue tumor examine impact residual (ReT) after UE. Nonmetastatic sarcomas surgically treated in 1996–2012 were included this study. Disease‐specific survival (DSS), metastasis‐free (MFS), local‐recurrence‐free (LRFS) stratified according location American Joint Committee on Cancer Classification 7th edition stage. Independent prognostic parameters identified by...
Prostate-specific membrane antigen (PSMA) is overexpressed in the neovasculature of renal cell carcinoma (RCC). However, there remains limited evidence regarding use PSMA positron emission tomography/computed tomography (PET/CT) RCC.To assess impact PET/CT management metastatic RCC.This was a retrospective review patients who underwent from 2014 to 2020 for restaging or suspected RCC tertiary academic setting.Management plans before and after were recorded. Impact classified as high (change...
Abstract Abstract: When local treatments for prostate cancer have failed, and prostate-specific antigen (PSA) rises in the absence of symptoms, there is little consensus as to best management strategy. Calcitriol has been shown prolong doubling time PSA this context, but near-toxic doses are required. We investigated effect nutrient vitamin D (cholecalciferol), a biochemical precursor calcitriol, on levels rate rise these patients. Fifteen patients were given 2,000 IU (50 μg) cholecalciferol...
Preoperative radiotherapy (RT) is commonly used to treat localised soft-tissue sarcomas (STS). Hypoxia an important determinant of radioresistance. Whether antiangiogenic therapy can 'normalise' tumour vasculature, thereby improving oxygenation, remains unknown. Two cohorts were prospectively enrolled. Cohort A evaluated the implications hypoxia in STS, using hypoxic tracer 18F-azomycin arabinoside (FAZA-PET). In cohort B, sunitinib was added preoperative RT a dose-finding phase 1b/2 design....
This study analyses seminal vesicle displacement relative to the prostate and in relation treatment time. A group of eleven patients undergoing cancer radiotherapy were imaged with a continuous 3 T cine-MRI standard setup position. Four images recorded every 4 seconds for 15 minutes sagittal plane 6.5 12 coronal plane. The gland vesicles contoured on each MRI image. coordinates centroid image was analysed against Displacements between 2.5 percentile 97.5 (i.e. 2.5% trimmed range)...
Reduction of respiratory tumour motion is important in liver stereotactic body radiation therapy (SBRT) to reduce side effects and improve control probability. We have assessed the distribution use voluntary exhale breath hold (EBH), abdominal compression (AC), free breathing gating (gating) (FB), impact these on treatment time.We all patients treated a single institution with SBRT between September 2017 2021. Data from pre-simulation management assessment using fluoroscopic dome position...
Abstract Background Lattice radiation therapy (LRT) alternates regions of high and low doses within the target. The heterogeneous dose distribution is delivered to a geometrical structure vertices segmented inside tumor. LRT typically used treat patients with large tumor volumes cytoreduction intent. Due geometric complexity target volume required distribution, treatment planning demands additional resources, which may limit clinical integration. Purpose We introduce fully automated method...
Abstract Background Stereotactic ablative body radiotherapy (SABR) is an emerging treatment for patients with primary renal cell carcinoma (RCC). However, its impact on function unclear. This study aimed to evaluate incidence and clinical factors predictive of severe end-stage chronic kidney disease (CKD) after SABR RCC. Methods materials was a Single institutional retrospective analysis diagnosed RCC receiving between 2012–2020. Adult no metastatic disease, baseline estimated glomerular...
Metastasis-directed therapy (MDT) in oligometastatic renal cell carcinoma (RCC) is typically based on conventional imaging. Prostate-specific membrane antigen (PSMA) PET/CT has shown superiority over Our objective was to perform a proof-of-concept study evaluate the efficacy of PSMA-guided MDT RCC. Methods: A PSMA database queried for RCC patients undergoing from 2014 2020. The primary endpoint progression-free survival. Secondary endpoints included freedom local progression, change systemic...
ABSTRACT Background Desmoid tumors (DT) are rare, locally aggressive neoplasms that affect a young population and have tendency for recurrence. There is sparse contemporary real‐world data to guide practice DT. Here, we report on large cohort of DT patients, describing patterns care clinical outcomes. Methods Data patients first seen between 2010 2021 were extracted from prospective database supplemented with retrospective review hospital records. Trends in treatment use analyzed using the...