- Dialysis and Renal Disease Management
- Diabetes Treatment and Management
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Organ Donation and Transplantation
- Central Venous Catheters and Hemodialysis
- Renal Transplantation Outcomes and Treatments
- Tuberculosis Research and Epidemiology
- Renal and Vascular Pathologies
- Acute Kidney Injury Research
- Organ Transplantation Techniques and Outcomes
- Blood Pressure and Hypertension Studies
- Systemic Lupus Erythematosus Research
- Vascular Procedures and Complications
- Pediatric Urology and Nephrology Studies
- Pregnancy and preeclampsia studies
- Renal cell carcinoma treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Palliative Care and End-of-Life Issues
- Pulmonary Hypertension Research and Treatments
- Electrolyte and hormonal disorders
- Hormonal Regulation and Hypertension
- Gout, Hyperuricemia, Uric Acid
- Vascular anomalies and interventions
- Metabolism and Genetic Disorders
Kasturba Medical College, Manipal
2016-2025
Manipal Academy of Higher Education
2017-2025
Creative Commons
2023
Father Muller Medical College Hospital
2023
Diabetes mellitus (DM) has emerged as the most common cause of chronic kidney disease (CKD) and end-stage renal (ESRD) globally in recent years. Diabetic nephropathy (DN), or diabetic (DKD) that occurs a direct consequence DM, complex pathophysiological mechanisms, such various inflammatory processes genetic epigenetic factors, often accentuated by comorbid illnesses like hypertension dyslipidemia. Therefore, management DKD involves targeting these etio-pathological processes. Various...
Arteriovenous fistula(AVF) is preferred vascular access for hemodialysis but has primary failure in 20-60%. Studying predictors of AVF would help plan appropriate management.We studied outcomes, clinical and factors predicting their patients requiring hemodialysis.Retrospective study with creation from January 2017 to December 2018. Outcomes were immediate (< 72 h), (3 months) failure, six-month/one-year patency, analyzed predictive clinical, as assessed using Pre-operative Doppler...
Pulmonary hypertension (PH) is an underestimated cardiovascular consequence and a mortality predictor in patients on hemodialysis (HD). Thus, we studied its prevalence, risk factors, association with inflammation/oxidative stress, cardiac changes HD patients.This was single-center cross-sectional observational study conducted at tertiary care hospital. Patients aged >18 years for least three months were included divided into those without PH; secondary causes PH excluded. Clinical...
Uremic pruritus has an impact on the quality of life and sleep hemodialysis patients, but majority cases go unreported untreated unless severe, due to a lack awareness. The purpose this study is determine prevalence, associated factors, health-related (HR-QOL) in patients.A single-center observational 3 months wherein 120 adults maintenance were included. Baseline characteristics, dialysis-related lab parameters influencing uremic recorded. Those with completed "12-item severity scale...
Abstract Percutaneous renal biopsy, although essential for disease diagnosis, is associated with a number of post-biopsy complications ranging from gross haematuria to AV fistula death. In this study, we carried out an active haematoma surveillance and attempted correlate sonological parameters—kidney length, parenchymal changes, cortical thickness their potential use in prediction post-renal biopsy complications. Methods This was prospective study done April 2022 2023 on all adult patients...
Introduction Patients with chronic kidney disease (CKD) are at increased risk of developing tuberculosis (TB). These patients may also be higher antitubercular treatment (ATT)-associated adverse drug reactions (ADRs). Although dose modification has been recommended, data regarding the impact impaired function on ATT-associated ADRs is sparse. We studied incidence and profile in CKD compared them those normal function.
Diabetic kidney disease (DKD) represents a unique subset of patients with chronic (CKD). Acute injury (AKI) is implicated in DKD progression; however, their interplay not studied well. We risk factors for AKI and the effect on progression homogeneous group DKD.We conducted retrospective open cohort study at single tertiary care centre between August 2016 - 2019. Patients minimum follow-up 2 years were included study. The incidence, etiology studied. primary outcome was reduction estimated...
Subcutaneous Panniculitis like T cell Lymphoma (SPTCL) is an uncommon variant and poorly differentiated type of cutaneous lymphoma. Here we describe the case a 19-year-old female who presented with swelling left half face no regional lymphadenopathy hepatosplenomegaly which was initially misdiagnosed as benign condition by various practitioners. Histopathological examination revealed diffuse infiltration subcutaneous plane small to medium sized atypical lymphocytes. Immunohistochemistry...
Introduction: In hemodialysis (HD) patients, catheter-related bloodstream infections (CRBSI) cause significant morbidity and mortality. Objectives: We analyzed dialysis CRBSI incidence, associated factors, the spectrum of causative organisms. Patients Methods: aged ≥18 years either on maintenance HD or with acute kidney injury having (NKF-KDOQI criteria) were included in this prospective observational study patients other excluded. Blood, catheter tip culture, antibiogram analyzed. All...
Introduction: Hyponatremia is a frequent finding in hospitalized patients and associated with poor clinical outcomes. While hyponatremia known to commonly occur certain infections, its association melioidosis has not been studied previously. We incidence impact of on outcomes melioidosis. Methods: This was retrospective analysis single-center hospital registry culture-positive during 10-year period (January 01, 2010, through January 31, 2021). defined as serum sodium <135 mmol/L, severe...
Snake bite continues to be one of the major and potential contributors for morbidity mortality in India. Intracranial haemorrhage causing neurological deficits is a known entity due snake but presentation with infarction rare. The authors report case healthy middle aged female who presented within hours envenomation altered sensorium evaluation revealed left hemiplegia deranged coagulation profile multiple ischaemic infarcts instead as consequence vasculotoxic viper bite.
Objectives: The existing biomarkers used to promptly identify graft dysfunction after kidney transplantation lack consistency. Neutrophil gelatinase-associated lipocalin (NGAL) appears be a promising biomarker but its levels measured from serum and urine have demonstrated varying predictive values. Our study aimed explore the potential of NGAL as in predicting transplant patients, including live deceased donor recipients. Methods: A single-centered observational cohort with recipients...
<ns3:p>Background Haematological abnormalities following renal transplantation are frequently observed and have a significant effect on survival graft outcomes. The pattern of haematological varies globally. Few studies been conducted in Asian countries. We aimed to evaluate the patterns post-transplant recipients our center during first year after post-renal transplant association anemia with function. Methods This single-center retrospective study was between 2014 2019. included all...