Ayşe Polat

ORCID: 0000-0002-1856-4387
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About
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Research Areas
  • Islamic Studies and History
  • Turkey's Politics and Society
  • Neonatal and fetal brain pathology
  • Neonatal Respiratory Health Research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Anesthesia and Neurotoxicity Research
  • Prenatal Screening and Diagnostics
  • Antibiotics Pharmacokinetics and Efficacy
  • Fetal and Pediatric Neurological Disorders
  • Respiratory Support and Mechanisms
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Cardiac Ischemia and Reperfusion
  • Nitric Oxide and Endothelin Effects
  • Liver Disease Diagnosis and Treatment
  • Advanced Neuroimaging Techniques and Applications
  • Urticaria and Related Conditions
  • Helicobacter pylori-related gastroenterology studies
  • Drug Transport and Resistance Mechanisms
  • Tumors and Oncological Cases
  • Hepatitis B Virus Studies
  • Hydrogen's biological and therapeutic effects
  • Medical and Biological Ozone Research
  • Historical Turkish Studies
  • MRI in cancer diagnosis
  • Neurogenetic and Muscular Disorders Research

Cornell University
2025

National Endowment for the Humanities
2025

Dokuz Eylül University
2014-2024

Oxfam
2022

John Wiley & Sons (United States)
2022

John Wiley & Sons (United Kingdom)
2022

Mersin Üniversitesi
2006-2021

Sheba Medical Center
2016-2017

Tel Aviv University
2016-2017

Ankara Sosyal Bilimler Üniversitesi
2012

10.1080/02757206.2024.2437479 article EN History and Anthropology 2025-01-14

Spinal muscular atrophies (SMAs) are a heterogeneous group of disorders characterized by atrophy, weakness, and hypotonia due to suspected lower motor neuron degeneration (LMND). In large cohort 3,465 individuals with SMA submitted for SMN1 testing our routine diagnostic laboratory, 48.8% carried homozygous deletion, 2.8% subtle mutation, an whereas 48.4% remained undiagnosed. Recently, several other genes implicated in SMA/LMND have been reported. Despite efforts establish algorithm...

10.1002/humu.23560 article EN Human Mutation 2018-06-02

Testicular dysfunction correlates with increased testicular mast cells. Mast cells can activate fibroblasts and promote collagen synthesis. The aim of the study was to examine containing tryptase, relationship between different fibrosis stages interstitium peritubular region testes. biopsies obtained from 33 infertile men were assigned 2 groups: normal spermatogenesis (n = 10) defective 23). Total, interstitial, examined immunohistochemically using antihuman tryptase. stage evaluated...

10.1080/01485010290099183 article EN Archives of Andrology 2002-01-01

<h3>BACKGROUND AND PURPOSE:</h3> Measuring the volume of fetal brain structures is challenging due to motion, low resolution, and artifacts caused by maternal tissue. Our aim was introduce a new, simple, Matlab-based semiautomated method measure in present normal volumetric curves measured. <h3>MATERIALS METHODS:</h3> The supratentorial brain, left right hemispheres, cerebellum, eyeballs measured retrospectively new MR imaging examinations 94 healthy fetuses. Four ratios were calculated....

10.3174/ajnr.a5349 article EN cc-by American Journal of Neuroradiology 2017-08-24

Among all parotid gland tumors, small cell cancer is rare, seen in only 1.7%. Tumoral findings the may sometimes be caused by metastasis, and diagnosis these patients made at this metastatic focus. A 59-year-old male patient presented with a 3 × 4-cm painless mass front of mandibula. malignant epithelial tumor was diagnosed after histopathologic examination fine-needle aspiration biopsy specimen. The did not give consent for urgent parotidectomy. One month later, he again, indicating growth...

10.1097/scs.0b013e3181d7f186 article EN Journal of Craniofacial Surgery 2010-05-01

Sulfasalazine, an inhibitor of cyclooxygenase, 5-lipoxygenase, and nuclear factor κB (NF-κB), has been found to alleviate oxidative damage, proinflammatory cytokine production, bile-duct proliferation, neutrophil infiltration, fibrosis. Therefore, it may have a potential effect in attenuating lipid peroxidation histologic liver damage patients with biliary obstruction sepsis.The aim this study was investigate the sulfasalazine on due obstructive jaundice (OJ) OJ lipopolysaccharide...

10.1016/j.curtheres.2009.08.005 article EN publisher-specific-oa Current Therapeutic Research 2009-08-01

The aim of this study was to evaluate the effectiveness tracheally delivered mesenchymal stem cells (MSC) on lung pathology in a hyperoxia-induced injury (HILI) model neonatal rats.For HILI model, rat pups were exposed 85-95% oxygen during first 10 days life. Rats divided into six groups: room-air normoxia (n = 11); room air, sham hyperoxia with normal saline as placebo 9); culture medium MSC 10); remaining after harvesting 8); and 17). Pathologic changes, number diameter alveoli, α-smooth...

10.1111/ped.12764 article EN Pediatrics International 2015-07-24

Abstract Introduction The goal of our study was to evaluate the diagnostic efficacy diffusion‐weighted imaging ( DWI ) in differentiation benign and malignant breast lesions. Methods Between J une 2012 M arch 2013, 60 patients with 63 lesions (age range 29–70 years, mean age 48.6 years) were included study. All lesions, except complicated cysts intra‐mammary lymph nodes, confirmed histopathologically. evaluated a 1.5 T esla MR scanner using dedicated bilateral coil. images obtained by echo...

10.1111/1754-9485.12273 article EN Journal of Medical Imaging and Radiation Oncology 2015-01-07

The role of nitric oxide in the pathogenesis chronic viral hepatitis is not known. Elevated production assumed to be responsible for pathological changes many inflammatory conditions, mainly via peroxynitrite, a potential oxidant that produced by reduction superoxide anion with oxide. intensity and distribution immunohistochemical staining intrahepatic inducible synthase were studied biopsy specimens obtained from 63 patients 13 elevated transaminase levels various aetiologies. Hepatic was...

10.1046/j.1365-2893.2002.00382.x article EN Journal of Viral Hepatitis 2002-11-01

To examine the effects of pentoxifylline (PTX) on regional pulmonary and systemic inflammation after meconium aspiration, we studied 26 anesthetized ventilated adult rats for 3 hours. Seventeen were instilled with human (1.5 mL/kg, 65 mg/mL) intratracheally. After instillation meconium, PTX (20 mg/kg, i.a.; n = 9) or saline (n 8) was given to subjects. Nine that not served as sham group. Meconium resulted in increased bronchoalveolar lavage (BAL) fluid tumor necrosis factor-α (TNF-α; P 0.004...

10.3109/01902148.2012.676704 article EN Experimental Lung Research 2012-04-10

There have been several published reports on metastatic lesions in the stomach, but number of cases limited due to low frequency condition.Metastatic stomach are usually asymptomatic.A 55-yearold man with known lung adenocancer exhibited epigastric pain, hematemesis, and melena.A bleeding, ulcerated gastric metastasis was found treated endoscopic therapy omeprazole.

10.3349/ymj.2006.47.2.276 article EN cc-by-nc Yonsei Medical Journal 2006-01-01

Alterations of the human epidermal growth factor receptor 2 (HER2) protooncogene have been implicated in carcinogenesis and prognosis breast cancer. A polymorphism has identified at codon 655 (ATC/isoleucine to GTC/valine [I655V]) transmembrane domain-coding region this gene, which may be associated with risk In study we aimed determine whether cancer is I655V HER2 655. The genomic DNA from patients control subjects underwent analysis by polymerase chain reaction-fragment length...

10.1089/dna.2007.0702 article EN DNA and Cell Biology 2008-08-23

Background: Trapidil has various properties including vasodilatation, inhibition of lipid peroxidation and platelet aggregation as well as, reduction of, the inflammatory response to injury. The aim present study was investigate effects trapidil on dexamethasone‐impaired colonic anastomotic healing in an experimental rat model. Methods: Twenty‐four Wistar rats underwent transsection primary anastomosis. Rats were divided into four groups six: group 1 (G1), control; 2 (G2) trapidil, 8 mg/kg...

10.1046/j.1445-2197.2003.02683.x article EN ANZ Journal of Surgery 2003-10-29

This study is aimed to determine the effect of ozone therapy in neonatal rats with experimentally induced hypoxic ischemic brain injury (HIBI).The included 7-d-old male Wistar that were randomized sham, control, 1, and 2 groups. All except those sham group kept a hypoxia chamber, then control given 0.5 mL saline. Those 1 mg kg-1 intraperitoneally, intraperitoneally.There significantly fewer apoptotic neurons right hemispheres groups than (p < 0.001 p 0.001, respectively). There 0.001)....

10.4149/bll_2018_015 article EN Bratislavské lekárske listy/Bratislava medical journal 2018-01-01
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