Jihan Hussein

ORCID: 0000-0002-1862-0385
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Research Areas
  • Fatty Acid Research and Health
  • Diet, Metabolism, and Disease
  • Biochemical effects in animals
  • Liver Disease Diagnosis and Treatment
  • Advanced Glycation End Products research
  • Drug-Induced Hepatotoxicity and Protection
  • Natural Antidiabetic Agents Studies
  • Chemotherapy-induced organ toxicity mitigation
  • Coenzyme Q10 studies and effects
  • Biochemical Analysis and Sensing Techniques
  • Pomegranate: compositions and health benefits
  • Medicinal Plants and Neuroprotection
  • Effects and risks of endocrine disrupting chemicals
  • Nanoparticles: synthesis and applications
  • Cannabis and Cannabinoid Research
  • Ginseng Biological Effects and Applications
  • Growth Hormone and Insulin-like Growth Factors
  • Biochemical Acid Research Studies
  • Phytoestrogen effects and research
  • Pharmacological Effects and Toxicity Studies
  • Eicosanoids and Hypertension Pharmacology
  • Phytochemicals and Antioxidant Activities
  • Curcumin's Biomedical Applications
  • Cancer, Lipids, and Metabolism
  • Hibiscus Plant Research Studies

National Research Centre
2016-2025

National Water Research Center
2013-2016

Background: Preterm birth is associated with an increased oxidant burden which places these infants at a higher risk of injury.Aims: This prospective study aimed to assess levels antioxidants and marker oxidative stress in preterm neonates.Objectives: (i) To compare anti-oxidants [vitamin A, vitamin E, catalase, total anti-oxidant status (TAS)] as well malondialdehyde level (MDA) (a lipid peroxidation) between full-term neonates; (ii) determine changes the values measured vitamins discharge...

10.1179/2046905515y.0000000017 article EN Paediatrics and International Child Health 2015-05-05

Diabetes is associated with an increase in the production of free radicals, reduction tetrahydrobiopterin (BH4, THB) levels and reduced bioavailability nitric oxide (NO) vascular walls. In this contribution, we probed effective role curcumin nanoparticles (CUR-NPs) that prepared via solvent evaporation nanoprecipitation technique as potential system to attenuate endothelial dysfunction. technique, Tween 60 (polysorbate) was used stabilizing agent for CUR-NPs protect such from further...

10.1016/j.biopha.2020.110688 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2020-09-17

Ulcerative colitis (UC) can be defined as inflammatory disorders of the gastrointestinal tract characterized by elevation pro-inflammatory cytokines and free radicals besides other chronic aspects. Thus, this work was designed to find out how far enhancing beneficial effects yogurt fortified with Malva parviflora (M. parviflora) leaves extract nanoemulsion in attenuating experimental ulcerative (UC). Sixty male albino rats were divided into six groups. After period, blood samples collected...

10.1016/j.jmrt.2020.10.047 article EN cc-by Journal of Materials Research and Technology 2020-10-23

Abstract Being the second leading cause of death globally, cancer has been a long-standing and rapidly evolving focus biomedical research practice in world. Recently, there growing interest cyanobacteria. This is particularly evident developing innovative anticancer treatments to reduce reliance on traditional chemotherapy. study investigates potential Spirulina maxima extract nanoemulsion (SMNE) technique improve delivery, stability, solubility S. (SME). SMNE, prepared three concentrations...

10.1038/s41598-024-82924-4 article EN cc-by Scientific Reports 2025-01-06

Hypertension is the most common entity globally, marked by high prevalence and heterogeneous pathophysiology. Oxidative stress a crucial area of investigation among potential etiologies. We examined hypothesis that blocking angiotensin type 1 (AT1) receptor with valsartan (VST) in self-nanoemulsifying delivery systems (SNEDS) loads liquisolid tablets (LST-1) or hydrochlorothiazide (VST/HCTZ) SNEDS (LST-2) comparison non-SNEDS (DCT-3 DCT-4) would lead to an improvement hypertension...

10.1007/s00210-025-03993-4 article EN cc-by Naunyn-Schmiedeberg s Archives of Pharmacology 2025-03-26

Evidence of oxidative stress was reported in individuals with Down syndrome. There is a growing interest the contribution immune system The aim this study to evaluate coenzyme Q10 and selected pro-inflammatory markers such as interleukin 6 tumor necrosis factor α children syndrome.Eighty-six (5-8 years age) were enrolled case-control from two public institutions. At time sampling, patients controls suffered no acute or chronic illnesses received therapies supplements. levels 6, α, Q10,...

10.1016/j.jped.2016.04.012 article EN cc-by-nc-nd Jornal de Pediatria 2016-10-20

Bronchial asthma is one of the top disabling diseases in pediatrics. Limited research has been studied association widely used plastic monomer bisphenol A (BPA) with childhood asthma.To compare levels urinary BPA asthmatic and control children to investigate implication among other risk factors for development asthma.This case-control study included 97 (45 52 healthy controls) aged 3-8 years. Asthmatic were diagnosed according Global initiative (GINA) guidelines. Sociodemographic assessed...

10.1177/0960327118758150 article EN Human & Experimental Toxicology 2018-02-14

To investigate the ability of docosahexaenoic acid (DHA)-loaded silver nanoparticles (AgNPs) in facilitating incorporation DHA cell membrane, improve membrane structure, and attenuate endothelial dysfunction experimental diabetes.DHA/AgNPs were prepared using a nanoprecipitation technique. Fifty male albino rats used this study; 10 them served as control group 40, groups, injected with streptozotocin. Then, groups subdivided into diabetic, diabetic treated DHA, AgNPs, DHA/AgNPs...

10.1177/0960327119843586 article EN Human & Experimental Toxicology 2019-04-24

Objective: Doxorubicin (Dox), an anthracycline antibiotic, has been widely used to treat cancer, principally hematological malignancies, and solid tumors. The administration of Dox is a topic concern in the medical community, as it frequently related dose-dependent cardiotoxicity. Therefore, present study was designed investigate protective potential date palm fruit extract on Dox-induced cardiotoxicity.Methods: A total 40 female albino rats were this classified into four groups including...

10.22159/ajpcr.2018.v11i7.24453 article EN Asian Journal of Pharmaceutical and Clinical Research 2018-07-07
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