A5015144409- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis C virus research
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Diet, Metabolism, and Disease
- Cancer, Lipids, and Metabolism
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Adolescent and Pediatric Healthcare
- Cardiovascular Disease and Adiposity
- Child and Adolescent Health
- Dermatological and COVID-19 studies
- Streptococcal Infections and Treatments
- Lung Cancer Treatments and Mutations
- Drug-Induced Hepatotoxicity and Protection
- Gastric Cancer Management and Outcomes
- Wnt/β-catenin signaling in development and cancer
- Pharmacological Effects of Natural Compounds
- Pancreatic and Hepatic Oncology Research
- Autoimmune and Inflammatory Disorders Research
- Radiopharmaceutical Chemistry and Applications
- Diabetes and associated disorders
- Nigella sativa pharmacological applications
- Pancreatic function and diabetes
- Bacterial Infections and Vaccines
Ain Shams University
2014-2025
Ain Shams University Hospital
2021-2024
King Fahad Hospital Jeddah
2013-2017
To evaluate the safety, efficacy and tolerability of Nigella sativa (N. sativa) in patients with hepatitis C not eligible for interferon (IFN)-α.Thirty virus (HCV) infection, who were IFN/ribavirin therapy, included present study. Inclusion criteria included: HCV or without cirrhosis, had a contraindication to IFN-α refused financial constraint therapy. Exclusion on infection B I virus, hepatocellular carcinoma, other malignancies, major severe illness, treatment non-compliance. Various...
Transarterial chemoembolization (TACE) is one of the standard treatments recommended for intermediate stage hepatocellular carcinoma (HCC). At same time, only little known about use radioembolization with Yttrium-90 microspheres (TARE Y-90) this subset patients. To perform comparative analysis between both locoregional therapies in HCCs. Primary endpoint was overall survival (OS), while safety, response rate and time-to-progression (TTP) were considered as secondary endpoints.We collected...
BACKGROUND AND AIM Currently, pegylated interferon is the most effective therapy for hepatitis C but its cost out of reach patients in developing countries. The aim this study was to assess response rate genotype-4 24 wks peg-interferon-α2b (Peg-IFN-α2b) and ribavirin (RBV) or interferon-α2b (IFN-α2b) with RBV amantadine (AMD) as an alternative option. METHODS In a controlled study, 180 biopsy-proven naïve chronic were allocated into three groups based on their financial affordability any...
Abstract Background The most common manifestations of infection with COVID-19 are fever, sore throat, dry cough, headache, and body aches. available evidence for successful safe pharmacological therapy against has not yet been identified, the possible relates to many adverse reactions. Taste disorders, petechiae, desquamative gingivitis, unspecific oral ulcerations, xerostomia, candidiasis related SARS-CoV-2 infection. Main abstract We reviewed literature regarding reported mucosal lesions...
Abstract: Objectives: Interferon (IFN) therapy is not affordable by the majority of Egyptian patients. Our aim was to tailor an effective and inexpensive regimen that ameliorates hepatic necro‐inflammatory activity among chronic hepatitis C (CHC) Methods: One hundred seventy naïve CHC patients with elevated alanine aminotransferase (ALT) (>1.5‐fold) detectable virus (HCV)‐RNA polymerase chain reaction, who cannot afford IFN‐based were randomly allocated either non‐interferon‐based...
Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.
Among patients with chronic liver disease, impairment in HRQOL has been reported. Hepatocellular carcinoma (HCC) is one of the major squeal diseases. So, relationship between subjective and HCC must be analysed. This study assessed effect on HRQOL, its loco-regional treatment HRQOL. Forty HCV related disease as a control group was enrolled study. Eighty top categorized according to modality (BCLC staging system) into GI; 40 treated radiofrequency ablation (RFA) GII; trans-arterial...
Abstract Background Globally, MAFLD becomes in the top list of causes liver disease. Its effect ranges from steatosis, metabolic steato-hepatitis to MAFLD-related cirrhosis and hepatocellular carcinoma. There is a growing evidence that HCC seems be different HCCs other pathologically, so purpose our study was assess on prognosis regarding outcome after management survival rate comparison group patients with HCV-related HCC. Results Twenty-nine related were included A, while 58 HCV enrolled...
Background: Viral hepatitis B and C are the leading causes of hepatocellular carcinoma (HCC). With obesity, metabolic-related disorders increasingly associated with a higher incidence nonviral HCC. This study aimed to investigate characteristics, tumor features, treatment outcomes, survival patients viral versus Methods: multicenter cohort was conducted at six tertiary care centers. Patients were recruited between February 2007 June 2022 follow-up recorded until death or end (July 2023). The...
Abstract Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer-related death worldwide. In United States, HCC ninth cancer deaths. Despite advances in prevention techniques, screening, new technologies both diagnosis treatment, incidence mortality continue to rise. Cirrhosis remains important risk factor for development regardless etiology. Hepatitis B C are independent factors cirrhosis. Alcohol consumption an additional States...
Abstract Aim of the work To test reliability fibroscan in detection fibrosis patients with Budd Chiari syndrome before and after endovascular intervention (after elimination hepatic congestion). Background transient elastography (TE) is a noninvasive methodology that has been used to monitor liver stiffness chronic viral hepatitis. One limitations for accurate assessment by TE congestion. Liver congestion can result from (BCS).The treatment BCS through restoring flow blood between portal...
The reference standard for portal venous pressure measurement which is clinically important estimating the. feasibility of resection hepatocellular carcinoma the hepatic gradient, is, invasive and expqnsive. present study evaluated noninvasive parameters assessment hypertension in Child A patients with on top hepatitis C virus. total 112 were subjected to clinical assessment, biochemical assay, ultrasonographic Doppler study, triphasic spiral abdominal computed tomography, upper...
Maturity onset diabetes of the young type 3 (MODY3) is a heterogeneous monogenic form mellitus caused by mutations in gene ''hepatocyte nuclear factor-1alpha'' (HNF-1alpha) which result poor insulin secretion response to glucose. The aim present study detect, for first time Egypt, HNF-1alpha Egyptian patients, and compare results patients with those other regions. This included eight diagnosed MODY3; their ages were between 12 17 years old. DNA extraction was carried out from blood samples,...
The reference standard for portal venous pressure measurement which is clinically important estimating the feasibility of resection hepatocellular carcinoma hepatic gradient, invasive and expensive.The present study evaluated noninvasive parameters assessment hypertension in Child A patients with on top hepatitis C virus.A total 112 were subjected to clinical assessment, biochemical assay, ultrasonographic Doppler study, triphasic spiral abdominal computed tomography, upper gastrointestinal...
HCV virus has been shown to induce insulin resistance (IR) itself. The aim of this work: was evaluate HCV-induced IR in Egyptian cirrhotic patients after LDLT and correlate the occurrence with level HCV-RNA viremia status disease recurrence post LDLT. 67 had received from November 2010 2012. 17 them were included prospective research by following criteria :1) Patients related End Stage Liver Disease , who eligible for liver transplantation . 2) an estimate using HOMA-IR more than or equal 2...
<h3>Objectives</h3> This study aimed at investigating the psychological functioning of Saudi children with poly-articular joint disease and its association activity disability. <h3>Methods</h3> One hundred twenty aged 6-16 years, juvenile idiopathic arthritis more than 4 joints involved were recruited. All Children classified according to revised World Health Organization ILAR classificationAll underwent a clinical examination. Clinical information was extracted from hospital records....
<h3>Objectives</h3> To examine the relation between chronic fatigue syndrome (fibromyalgia), disease activity, and quality of life measures in patients with systemic lupus erythematosus (SLE). <h3>Methods</h3> Consecutive 40 attending king fahad hospital, Jeddah Saudi German Jeddah; were studied. All fulfilled American college rheumatology (ACR) criteria for Classficiation SLE. Disease activity was assessed using SLE index (SLEDAI) Fatigue measured by Severity Score (FSS) health status SF-36...
Among patients with chronic liver disease, impairment in HRQOL has been reported.Hepatocellular carcinoma (HCC) is one of the major squeal diseases.So, relationship between subjective and HCC must be analysed.This study assessed effect on HRQOL, its loco-regional treatment HRQOL.Forty HCV related disease as a control group was enrolled study.Eighty top categorized according to modality (BCLC staging system) into GI; 40 treated radiofrequency ablation (RFA) GII; trans-arterial...