Ayşe Kefeli

ORCID: 0000-0002-1876-2586
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About
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Liver Disease Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Gallbladder and Bile Duct Disorders
  • Eosinophilic Esophagitis
  • Hepatitis C virus research
  • Liver Disease and Transplantation
  • Colorectal Cancer Screening and Detection
  • Hepatitis B Virus Studies
  • Cancer, Lipids, and Metabolism
  • Gastrointestinal Tumor Research and Treatment
  • Biliary and Gastrointestinal Fistulas
  • Gastroesophageal reflux and treatments
  • Esophageal and GI Pathology
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Coronary Artery Anomalies
  • Vascular anomalies and interventions
  • Intestinal and Peritoneal Adhesions
  • Esophageal Cancer Research and Treatment
  • Abdominal vascular conditions and treatments
  • Eosinophilic Disorders and Syndromes
  • Galectins and Cancer Biology
  • Veterinary medicine and infectious diseases

Tokat Gaziosmanpaşa Üniversitesi
2016-2024

Kocaeli Üniversitesi
2022

Siirt Üniversitesi
2015-2017

State Hospital
2015-2016

Education Training And Research
2016

S.B. Keçiören Eğitim ve Araştırma Hastanesi
2011-2015

Ministry of Health
2014

It is shown that there are strong associations between nonalcoholic fatty liver disease (NAFLD) and endothelial dysfunction. The aim of our study was to reveal whether steatosis or fibrosis score more important in the development dysfunction patients with NAFLD a prospective manner. This cross-sectional included 266 subjects. These subjects were divided into 2 groups depending on presence hepatosteatosis sonographically. Patients also 3 subgroups degree steatosis: grade 1, 2, 3. In all...

10.1097/md.0000000000003280 article EN cc-by-nc Medicine 2016-04-01

Vitamin D deficiency has been related to diabetes, hypertension, hyperlipidemia and peripheral vascular disease. In this study, we aimed investigate the role of vitamin status in non-alcoholic fatty liver disease.We included 211 consecutive subjects examine presence Of these subjects, 57 did not have disease 154 had disease.The group significantly higher fasting blood glucose (p = 0.005), uric acid 0.001), aspartate aminotransferase (p<0.001), alanine γ-glutamyltransferase (p<0.0001),...

10.6061/clinics/2014(08)07 article EN cc-by-nc Clinics 2014-08-01

Treatments with bismuth-containing quadruple therapy (QT), sequential (ST), or concomitant (CT) have been proposed as empirical first-line regimens for Helicobacter pylori. We compared the efficacy and tolerability of 10 days QT, ST, CT treatments H. pylori in a randomized crossover study. The subjects were randomly divided into three groups. first 130 patients treated rabeprazole, bismuth potassium citrate, metronidazole, tetracycline days. second group rabeprazole amoxicillin 5 days, then...

10.17305/bjbms.2016.660 article EN Bosnian Journal of Basic Medical Sciences 2015-12-17

The aim of our study was to investigate the underlying causes behind etiology cirrhosis in Türkiye. comprised patients with located gastroenterology clinics 28 centers Türkiye between January 2000 and June 2021. group consisted 4953 cirrhotic (median age: 62.2 years, male / female: 58% 42%). Among patients, 39% were compensated, 61% decompensated. Furthermore, 47.5% had Child-Pugh class A, 38% ChildPugh B, 14.5% C. most frequent complaints abdominal bloating (28%). Ascites (54.2%) common...

10.5152/tjg.2024.23572 article EN cc-by The Turkish Journal of Gastroenterology 2024-09-05

Colorectal neoplasm (CRN) and coronary heart disease (CHD) share common risk factors. We aimed to assess the for CRN in patients who are at high developing CHD determined by measurements, which independent from factors CRN.This study was conducted on individuals underwent total colonoscopic examination were without history of CHD. Two-hundred thirty-five subjects (82 with 153 normal findings) participated study. carcinoma (CRC) defined as presence adenocarcinoma. measured carotid intima...

10.1097/md.0000000000000793 article EN cc-by-nc Medicine 2015-05-01

Background . Early diagnosis of gastric cancer is one the most important parameters affecting survival disease. In this study, we aimed to stress importance antrum wall thickness in CT examination. Method The study included 111 patients between ages 18 and 95 who had antral thickening computed tomography also endoscopic evaluation performed same clinic. were divided into two groups as benign malignant according pathology results. tomography, hemoglobin albumin levels, age was compared among...

10.1155/2019/8581547 article EN Journal of Oncology 2019-11-20

Background: Helicobacter pylori (H.pylori) is associated with chronic gastritis, peptic ulcers, gastric adenocarcinomas and mucosa tissue lymphomas. Cytotoxin gene A (CagA) one of the virulence factors H.pylori. It hypothesized that reactive oxygen species (ROS) play roles in H.pylori disease especially development adenocarcinoma. Individuals infected bearing CagA produce more ROS than others. 8-hydroxydeoxyguanosine (8OHdG) an vitro marker DNA damage oxidative stress. The aim this study was...

10.7314/apjcp.2015.16.13.5199 article EN cc-by Asian Pacific Journal of Cancer Prevention 2015-08-03

Objective: Ingested foreign bodies in gastrointestinal tract are a common event which can cause serious morbidity and mortality the children adult population.For this reason, early diagnosis treatment crucial for preventing these life threatening complications.In study, we aimed to analyze characteristics of patients with upper that were treated our department.Methods: Patients diagnosed who admitted hospital between February 2010 August2013 evaluated retrospectively.The data regarding their...

10.5798/diclemedj.0921.2014.01.0398 article EN cc-by-nc Dicle Medical Journal / Dicle Tip Dergisi 2014-03-01

Background/aim: The incidence of acute cholecystitis (AC) increases with age, and aging is also one the poor prognostic factors. Aging related to altered physiology, so diseases may show different characteristics in elderly patients. We aimed investigate differences between main characteristic features AC nonelderly Materials methods: In this retrospective study, patients who had a diagnosis were included divided into two groups people aged

10.3906/sag-1507-13 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2016-01-01

Helicobacter pylori infection is a common worldwide. The most frequently recommended treatment for eradication of H. remains triple therapy. In this study, we compared sequential and hybrid regimens in region Turkey with high resistance to clarithromycin.Three hundred forty pylori-positive patients were enrolled the study. subjects randomly divided into two groups. first group (170 patients) received rabeprazole (40 mg/b.i.d.) amoxicillin (1000 2 weeks metronidazole clarithromycin (500...

10.5114/aoms.2016.58595 article EN cc-by-nc-sa Archives of Medical Science 2016-03-22

Purpose/Aim of the study: The main purpose colonoscopy is screening for colorectal cancers and diagnosis disease cost-effectiveness directly depend on adequate bowel preparation. Inadequate recommended to be re-scheduled within 1 year. Re-scheduling an economic patient burden. Thus instead re-scheduling, another strategy may attempted. this study was examine usefulness effect same day repeat after administration additional laxative dose. Materials Methods: Patients with inadequate were...

10.1080/08941939.2018.1513611 article EN Journal of Investigative Surgery 2018-10-31

BACKGROUND:In developing countries, esophageal burns are quite common.They caused by the ingestion of corrosive substances that may lead to perforation in short-term and stricture formation long-term.Prevention progression esophagus is main aim treatment for burns.We aimed investigate protective anti-inflammatory effects methylene blue (MB) on burns. METHODS:Twenty-eight rats were used study randomly divided into four equal groups; group 1 (Sham), 2 (control), 3 (topical treatment), 4 plus...

10.5505/tjtes.2018.58506 article EN Turkish Journal of Trauma and Emergency Surgery 2018-01-01

EJOHG IntroductIonPolyp presents formations of protruding lesions into the lumen gastrointestinal tract.In other words, luminal protrusion or elevation mucosal surfaces are called polyp. 1 In literature, first cases polyps have been reported about 300 years ago.Polyp can be asymptomatic; however, they also cause abdominal pain, anemia, bleeding obstruction.Polyps, especially to those who adenomatous types, may become malignant.For this reason, detected during colonoscopy, regardless size...

10.5005/jp-journals-10018-1088 article EN Euroasian Journal of Hepato-Gastroenterology 2014-01-01

is a critical initiating event that leads to autodigestion of pancreas. 3lthough radiological imaging modalities, pathologic and biochemical analysis are commonly used monitor pancreatic inflammation, great number invasive/ noninvasive methods also been studied for AP diagnosis determining the disease activity.But, role platelets in pathophysiology has not clearly elucidated yet.In this setting, main aim present study was evaluate platelet size alterations between onset remission disease....

10.5005/jp-journals-10018-1104 article EN Euroasian Journal of Hepato-Gastroenterology 2013-07-01

10.1590/0102-6720201600010020 article EN ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo) 2016-03-01

Acute pancreatitis (AP) is an inflammatory disorder, the incidence of which has been increasing over recent years. Mean platelet volume (MPV) index activation and influenced by inflammation. The objective present study to assess whether MPV would be convenient parameters for predictor factor patients with AP.A total 140 AP (male/female: 63/77) 70 healthy subjects 23/47) were enrolled in this study. following data extracted from hospital medical records, including age, sex, count, MPV,...

10.5005/ip-journals-10018-1104 article EN PubMed 2014-07-01

Amaç: Karaciğer sirozu sebepleri yönünden önlenebilir bir hastalık olduğu için epidemiyolojisinin araştırılması önemlidir

10.5798/diclemedj.0921.2015.04.0601 article TR cc-by-nc Dicle Medical Journal / Dicle Tip Dergisi 2015-12-01

Ulcerative colitis (UC) and Crohn's disease (CD) are two varieties of inflammatory bowel (IBD). Clinicians need a monitoring technique in the IBD. The activity can be assessed with endoscopy, indexes, imaging techniques. Color Doppler US (CDUS) is also non-invasive, radiation, contrast material free examination which shows intramural blood flow.To evaluate usefulness B-mode, CDUS, newly developed software Quantification (CQ) to determine IBD.The was by clinical indexes. Caecum, terminal...

10.2174/0929867328666201228124621 article EN Current Medical Imaging Formerly Current Medical Imaging Reviews 2020-12-29

Acute upper gastrointestinal bleeding (UGIB) is a common indication for endoscopy, with large audit reporting 14% mortality [1,2]. Although, the tract most site of lymphoma, lymphoma rare cause [3]. In this paper, we present case non-Hodgkin’s Lymphoma (NHL) resulting in massive bleeding.

10.4172/2327-5146.1000234 article EN General Medicine Open Access 2016-01-01
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