A5040144959- Iron Metabolism and Disorders
- Research on Leishmaniasis Studies
- Hemoglobinopathies and Related Disorders
- Blood donation and transfusion practices
- Autoimmune and Inflammatory Disorders Research
- Academic Research in Diverse Fields
- Cancer, Hypoxia, and Metabolism
- Blood transfusion and management
- HIV/AIDS Research and Interventions
- Pineapple and bromelain studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Metabolism, Diabetes, and Cancer
- T-cell and Retrovirus Studies
- Urticaria and Related Conditions
- Biochemical and Molecular Research
- Lysosomal Storage Disorders Research
- Cancer-related Molecular Pathways
- Parasites and Host Interactions
- Immune Response and Inflammation
- Trypanosoma species research and implications
- Injury Epidemiology and Prevention
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais
2020-2024
Universidade Estadual de Montes Claros
2016-2024
// Talita Antunes Guimarães 1 , Lucyana Conceição Farias Eliane Sobrinho Santos 1, 5 Carlos Alberto de Carvalho Fraga 6, 7 Lissur Azevedo Orsini 2 Leandro Freitas Teles John David Feltenberger 3 Sabrina Ferreira Jesus Marcela Gonçalves Souza Sérgio Henrique Sousa 4 Alfredo Maurício Batista Paula Ricardo Santiago Gomez 2, * André Luiz Sena Department of Dentistry, Universidade Estadual Montes Claros, Minas Gerais, Brazil Clinical, Surgery and...
Visceral leishmaniasis (VL) is an ill-studied disease that endemic to several regions of Brazil. It often complicated by hemophagocytic lymphohistiocytosis (HLH), a potentially fatal disorder resulting from excessive non-malignant activation/proliferation T lymphocytes and macrophages. Considering the overlapping clinical laboratory characteristics these diseases, diagnosing HLH challenge. Therefore, tracking association between VL necessary in areas. Although can be inapparent resolve with...
Inconclusive serological screening for Trypanosoma cruzi has been a problem blood banks.This study examined the performance of techniques Chagas disease in reagent samples from bank screenings and verified possibilities cross reactivity with visceral leishmaniasis. 68 donors tested ELISA were evaluated by other detection anti-Leishmania antibodies.Four (5.9%) positive results T. Kalazar Detect (visceral leishmaniasis),three which confirmed Western blot. This confirms specificity tests banks...
Objective: This study aims to analyze blood donation candidates' clinical and epidemiological profiles in Northern Minas Gerais, Brazil, from 2019 2022. Methods: We retrospectively searched the donor data Montes Claros’ Hemotherapy Center/ Hemominas Foundation January December Clinical variables were assessed using a bank database. Main Results: Of 81,195 candidates, majority female, over 29 years old, repeat donors, replacement donations. Among them, 18.96% deemed ineligible, with being Key...
This cross-sectional, quantitative and descriptive study assessed the level of information about sickle cell disease among educators in public schools Montes which there are students with SS homozygous subtype (sickle anemia). There were 136 research, 94.9% them teachers, 2.9% principals 1.5% supervisors We found that 67.6% had no knowledge enrolled disease, 83.1% heard 47.8% classified it as an hereditary 39% related to nutrient defficiency, 64.7% could not differentiate between traits,...
Abstract Background Visceral leishmaniasis (VL) is a serious public health problem. The factors that can determine whether VL develops and progresses to severe form have not been fully identified, but specific cellular immune response appears play key role. Therefore, understanding immunopathogenesis be useful in preventing clinical outcome. Materials Methods Bone marrow samples were collected from patients with (SVL) or non‐severe (NSVL). Cytokine levels parasitic load analysed by RT‐qPCR....
As hemofilias são doenças hemorrágicas determinadas pela deficiência de fator VIII (hemofilia A) ou IX B) da coagulação. Foi objetivo esse estudo analisar o impacto hemofilia nas atividades escolares, laborais e lazer pacientes atendidos no Hemocentro Regional Montes Claros/MG. Trata-se transversal, descritivo, quanti- qualitativo realizado a partir entrevista dados prontuários. Os foram submetidos à análise estatística. Participaram pesquisa 22/43 indivíduos masculinos, maiores 18 anos, com...
Objetivo: Avaliar a adesão ao tratamento de pessoas com doença falciforme acompanhadas em um hemocentro da região norte Minas Gerais. Métodos: Estudo observacional, descritivo, conduzido partir avaliação prontuários e aplicação questionários 70 portadores falciforme, posterior análise estatística descritiva. O estudo foi aprovado pelo Comitê Ética Pesquisa. Resultados: Dentre amostra, 57,1% eram do sexo feminino 55,7% tinham até 17 anos. 78,6% residiam entre 101 400 km distância 74,3%...
A hemofilia é uma doença hemorrágica hereditária e um dos principais desafios do seu tratamento o desenvolvimento de inibidores. O objetivo desse trabalho foi discutir a literatura que trata da presença inibidores face à abordagem diagnóstica, terapêutica impacto na qualidade vida. Trata-se estudo revisão composto por 81 artigos, utilizaram-se os descritores "Hemofilia" "Inibidores Fatores Coagulação". Conclui-se reflete interação entre vários fatores como mutação genética, resposta imune,...
Este estudo analisou indicações e eventos adversos transfusionais que ocorreram no Hospital Universitário Clemente Faria, localizado em Montes Claros/MG. Foi realizado um transversal, retrospectivo, quantitativo descritivo. Foram coletados dados de prontuários, registros do setor prova cruzada ficha notificação transfusionais. A pesquisa teve a aprovação CEP da UNIMONTES. No período 11/2018 06/2019 foram transfundidos 1592 hemocomponentes HUCF, concentrado hemácias (54,6%), 545 plaquetas...