A5101834922- MicroRNA in disease regulation
- Advanced biosensing and bioanalysis techniques
- RNA Interference and Gene Delivery
- Immune cells in cancer
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- Vascular Tumors and Angiosarcomas
- Angiogenesis and VEGF in Cancer
- RNA modifications and cancer
- TGF-β signaling in diseases
- Occupational and environmental lung diseases
- Neurogenesis and neuroplasticity mechanisms
- Endometriosis Research and Treatment
- Sarcoma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Vascular Malformations and Hemangiomas
- Nerve injury and regeneration
- Connective Tissue Growth Factor Research
- Endometrial and Cervical Cancer Treatments
- Tumors and Oncological Cases
- Neuroscience and Neuropharmacology Research
- Central Venous Catheters and Hemodialysis
- Epigenetics and DNA Methylation
Inner Mongolia Maternal and Child Health
2023
Central South University
2005-2021
Xiangya Hospital Central South University
2005-2021
Ovarian cancer (OC) is a frequently lethal gynecologic malignancy, characterized by poor prognosis and high recurrence rate. The immune microenvironment has been implicated in the progression of OC. We landscape primary malignant OC ascites using single-cell bulk transcriptome raw data acquired from Gene Expression Omnibus Cancer Genome Atlas databases. then used CIBERSORT deconvolution algorithm, weighted gene co-expression network analysis, univariate multivariate Cox analyses, LASSO...
Abstract Background Most ovarian cancer patients with poor prognosis and immune microenvironment play a vital role in the progression of cancer. We aim to develop tumor-associated macrophage related gene (TAMRGs) prognostic signature that can stratify predict overall survival for Methods acquired single cell bulk transcriptome raw data from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO). landscape was identified primary ascites CIBERSORT deconvolution algorithm, Weighted...
Abstract: Childhood hemangioma is a common benign tumor composed of vascular endothelial cells that occurs mostly in children, with high incidence rate, generally 4–10%. The rate as 75% within few weeks after birth, especially the skin and subcutaneous tissue. Hemangioma can be invasive, growing rapidly, may lead to spontaneous ulceration. It also regress on its own. When it affects multiple areas head face, create significant mental psychological burden for both children parents. Treatment...
Objective To explore the role of TGF-βand TGIF in pathogenesis endometriosis. Methods The expression TGF-β and was detected by immunohistochemistry method ectopic eutopic endometrium 30 cases with endometriosis (ec-topic group group) normal 40 without (control group). Result TGF -β significantly higher than that control (P 0.05). lower group( P There were negative correlation between expressions - β endome-trium group(rs= 0.769, 0.549, < Conclusion abnormal pa-tients may be associated...