Mahesh Shanmugam

ORCID: 0000-0002-1912-4412
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About
Contact & Profiles
Research Areas
  • Ocular Oncology and Treatments
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • Retinal and Macular Surgery
  • Glaucoma and retinal disorders
  • Intraocular Surgery and Lenses
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal Imaging and Analysis
  • Retinal Development and Disorders
  • Cancer-related Molecular Pathways
  • Ocular Disorders and Treatments
  • Traumatic Ocular and Foreign Body Injuries
  • Ocular Infections and Treatments
  • Cerebral Venous Sinus Thrombosis
  • Vascular Malformations Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Corneal Surgery and Treatments
  • Cutaneous Melanoma Detection and Management
  • Immunotherapy and Immune Responses
  • Drug-Induced Ocular Toxicity
  • melanin and skin pigmentation
  • T-cell and B-cell Immunology
  • Connective tissue disorders research
  • Anesthesia and Pain Management
  • Nonmelanoma Skin Cancer Studies

Eye Hospital in Bangalore
2013-2024

Creative Commons
2023-2024

Manipal Academy of Higher Education
2024

Kasturba Medical College, Manipal
2024

Apollo Hospitals
2021

The California Eye Institute
2020

W.K. Kellogg Foundation
2020

University of Michigan
2020

Indian Institute of Technology Madras
2017

Chettinad Health City
2014

To investigate the relationship between myopia and macular thickness, as measured by optical coherence tomography.A total of 143 normal subjects comprising 80 eyes with high (spherical equivalent [SE] < -6.0 D), 37 low to moderate (SE -0.5 26 nonmyopic > D) were analyzed in this cross-sectional study. Total average, foveal, inner outer average thicknesses StratusOCT (Carl Zeiss Meditec Inc., Dublin, CA) compared among three diagnostic groups. Associations thickness refractive error/axial...

10.1167/iovs.06-0426 article EN Investigative Ophthalmology & Visual Science 2006-12-29

To compare the safety and efficacy of different doses intravitreal triamcinolone (ivTA) in treating clinically significant diabetic macular oedema (CSMO).63 eyes 63 patients with CSMO central foveal thickness (CFT) > or =250 microm on optical coherence tomography were randomised to receive 4 mg (n = 23), 6 20) 8 ivTA. Patients followed up for months, changes best-corrected visual acuity (BCVA), CFT, standardised change (SCMT), side effects such as intraocular pressure cataractogenesis...

10.1136/bjo.2006.102848 article EN British Journal of Ophthalmology 2006-09-15

Purpose To describe the clinical characteristics of retinal detachments in patients with Marfan syndrome and report surgical outcome vitreoretinal surgery. Methods Records relating to 53 eyes 45 who underwent surgery for rhegmatogenous detachment were reviewed. Of eyes, 24 (45.3%) scleral buckling as first procedure 29 (54.7%) vitrectomy buckle procedure. Main measures included detachment, reattachment rates, functional improvement vision. Results Characteristic findings total 40 (75.5%)...

10.1097/00006982-200208000-00005 article EN Retina 2002-08-01

The aim of this study is to compare the optical coherence tomography angiography (OCTA) and fundus fluorescein (FFA) features retinal capillary hemangioblastoma (RCH). This an observational case series three patients with von Hippel–Lindau (VHL) disease one patient juxtapapillary RCH. All underwent FFA a mydriatic camera OCTA swept-source angio OCT. characteristics tumors were compared. In our series, could identify as small width third-order artery, which was missed on clinical examination....

10.4103/ijo.ijo_1199_17 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2018-01-01

A 40-year-old lady came to the clinic with presbyopic complaints since 1 month. Her best corrected visual acuity was 20/20, N6 (OU). Anterior segment evaluation as well Intraocular pressure within normal limits (WNL). Fundus examination of left eye (OS) revealed a circumscribed, elevated and opaque lesion 3 × 2.4 mm in size along inferior arcade [Fig. 1a]. Right fundus WNL. Autofluorescence showed moderate hyperaurofluorescence mass 1b]. Optical coherence tomography (OCT) through an...

10.4103/ijo.ijo_894_19 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2019-01-01

A deep learning system (DLS) using artificial intelligence (AI) is emerging as a very promising technology in the future of healthcare diagnostics. While concept telehealth every field medicine, AI assistance diagnosis can become great tool for successful screening telemedicine and teleophthalmology. The aim our study was to assess acceptability AI-based retina screening.This prospective non-randomized performed outpatient department tertiary eye care hospital. Patients older than 18 years...

10.4103/ijo.ijo_1840_21 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2022-03-22

To study the histopathologic features of 232 enucleated eyes with retinoblastoma.Two hundred thirty-two retinoblastoma in a tertiary-care institute from 1982 to 2001 were reviewed. Data collected and analyzed about type growth presence or absence vitreous subretinal seeding, rosettes fleurettes, necrosis, calcification, iris neovascularization, invasion anterior chamber, iris, choroid, optic nerve, sclera. Choroidal was graded using new system. Results for statistical significance.The...

10.3928/0191-3913-20030901-05 article EN Journal of Pediatric Ophthalmology & Strabismus 2003-09-01

purpose. This study was conducted to investigate the potential of targeting epithelial cell adhesion molecules (EpCAMs) in treatment retinoblastoma. It first determined whether EpCAM is expressed retinoblastoma and then reactivity correlates with tumor aggressiveness. methods. evaluated by immunohistochemistry 43 specimens from patients, using monoclonal antibody GA733.2. The tumors were divided into two groups. There 20 no invasion choroid optic nerve (group A) 23 choroid, nerve, orbit B)....

10.1167/iovs.04-0591 article EN Investigative Ophthalmology & Visual Science 2004-11-22

The intraocular manifestations of rickettisial retinitis include retinal vasculitis, maculopathy, optic neuritis, and neurosensory detachment. Extensive leakage dye on the fundus fluorescein angiography may obscure visualization in eyes with retinitis. We report vascular changes rickettsial its response to treatment using optical coherence tomography angiography. microvascular abnormalities we noted were, capillary drop out areas corresponding patches, loops, pruning vessels. choriocapillary...

10.4103/ijo.ijo_799_18 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2019-01-01

Purpose: To report the rare occurrence of subretinal fibrosis in patients with multifocal central serous chorioretinopathy and evaluate role systemic corticosteroids effects laser photocoagulation on leaks. Methods: A total 29 (mean age, 37.7 years; 89.7% male) treated for from 1983–1995 were reviewed retrospectively. Mean follow up was 26 months (range, 6.8–81 months). Results: Retinal detachment involved macula 72.4% cases. Fluorescein angiography showed a mean 6.7 2–22) leaks 1.8 1–5)...

10.1097/00006982-199801000-00005 article EN Retina 1998-01-01

To report causes of failure, management options, and outcomes after reoperations for recurrent retinal detachment in silicone oil-filled eyes.One hundred eighteen eyes with were managed revision vitrectomy membrane surgery or without oil removal, just scleral buckling, both. Anatomical success was defined as complete reattachment the retina, functional recovery ambulatory visual acuity >or=5/200 at last follow-up (mean follow-up, 29.7 months).In 82.2% cases, proliferative vitreoretinopathy...

10.1097/00006982-200204000-00003 article EN Retina 2002-04-01
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